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Questions and Answers
What are the main factors that affect the choice of route of drug administration?
What are the main factors that affect the choice of route of drug administration?
- Physical and chemical properties of the drug, site of desired action, and accuracy of dosage
- Physical and chemical properties of the drug, site of desired action, and rate of elimination
- Physical and chemical properties of the drug, rate and extent of absorption, and effect of digestive juices (correct)
- Site of desired action, accuracy of dosage, and rate and extent of absorption
Which route of drug administration may be used to produce local effects within the gastrointestinal tract?
Which route of drug administration may be used to produce local effects within the gastrointestinal tract?
- Subcutaneous route
- Intramuscular route
- Oral route (correct)
- Intravenous route
Which type of drugs are poorly absorbed because they are fully ionized in the gut?
Which type of drugs are poorly absorbed because they are fully ionized in the gut?
- Weakly basic drugs (correct)
- Polar drugs
- Nonpolar drugs
- Weakly acidic drugs
What are the two main mechanisms of drug absorption by the gut?
What are the two main mechanisms of drug absorption by the gut?
Which mechanism is the most important for drug absorption by the gut?
Which mechanism is the most important for drug absorption by the gut?
What is the main reason for non-polar lipid-soluble agents being well absorbed from the gut?
What is the main reason for non-polar lipid-soluble agents being well absorbed from the gut?
Which mechanism is responsible for the absorption of naturally occurring polar substances?
Which mechanism is responsible for the absorption of naturally occurring polar substances?
What can interfere with the absorption of several drugs following surgical interference with gastric function?
What can interfere with the absorption of several drugs following surgical interference with gastric function?
What may affect drug absorption by interrupting enterohepatic recycling and causing loss of efficacy of oral contraceptives?
What may affect drug absorption by interrupting enterohepatic recycling and causing loss of efficacy of oral contraceptives?
What is the aim of sustained-release preparations for rapidly eliminated drugs?
What is the aim of sustained-release preparations for rapidly eliminated drugs?
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