Drug Absorption Process Quiz

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What is drug absorption?

The process of movement of unchanged drug from the site of administration to systemic circulation.

How can the effectiveness of a drug be assessed?

By its concentration at the site of action, although it is difficult to measure. Alternatively, the concentration can be measured more accurately in plasma.

What is the significance of the rate and extent of absorption in drug therapy?

The rate and extent of absorption are significant in determining the therapeutic response and effectiveness of a drug.

What is the definition of absorption in relation to the site of measurement (plasma)?

The process of movement of unchanged drug from the site of administration to the site of measurement, i.e. plasma. Signup and view all the answers

Why is absorption considered an important prerequisite step for drugs intended to act systemically?

Because such drugs can exert their pharmacological actions only when they come into blood circulation from their site of application. Signup and view all the answers

How does drug concentration in plasma relate to the therapeutic response?

There always exists a correlation between the plasma concentration of a drug and the therapeutic response. Signup and view all the answers

What are the disadvantages of intravenous (IV) drug administration?

Increased chance for adverse reaction, possible anaphylaxis, tissue damage at the site of injection Signup and view all the answers

What are the advantages of a drug that is rapidly absorbed?

Higher blood levels and rapid onset of action, more uniform, greater, and reproducible therapeutic response Signup and view all the answers

What is the most common route for the administration of the majority of drugs?

Gastrointestinal (GI) route Signup and view all the answers

What are the advantages of enteral drug administration via the buccal or sublingual route?

Rapid absorption Signup and view all the answers

What are the advantages of intravenous (IV) drug administration?

Complete (100%) systemic drug absorption, drug is given for immediate or controlled effect, may inject large fluid volumes Signup and view all the answers

What are the advantages of enteral drug administration via the intramuscular route?

Rapid absorption from aqueous solutions, easier to inject than intravenous injection Signup and view all the answers

What are the disadvantages of subcutaneous (SC) drug administration?

Variable rates of absorption depending upon the muscle group injected and blood flow, rate of drug injection Signup and view all the answers

What are the advantages of enteral drug administration via the rectal route?

Lesser susceptibility of the drug for degradation or interaction due to rapid absorption Signup and view all the answers

What are the advantages of enteral drug administration via the gastrointestinal (GI) route?

Most common for administration of majority of drugs Signup and view all the answers

What are the advantages of enteral drug administration via the topical route?

Specific membranes, e.g., skin, eyes, intranasal, inhalation, intravaginal, transdermal Signup and view all the answers

Drug Absorption Process Quiz

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