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Questions and Answers
What is the characteristic of Reovirus?
What is the primary site of Rotavirus infection?
What is the main complication of Rotavirus infection?
What is the mechanism of Rotavirus-induced diarrhea?
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What is the recommended timing for the first dose of Rotavirus vaccine?
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What is the population most at risk for Rotavirus infection?
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What is the typical duration of Rotavirus infection?
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What is the primary treatment for Rotavirus infection?
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What is unique about the genetic material of Reovirus?
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What is the function of NSP4 in Rotavirus infection?
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What is the structure of the Rotavirus capsid?
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What is the result of enterocyte damage in Rotavirus infection?
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What is the significance of the boat name 'CHLO-RIDER' in the context of Rotavirus?
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What is the characteristic of Rotavirus outbreaks?
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What is the result of Rotavirus infection on the small intestine?
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Why is the Rotavirus vaccine typically administered orally?
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Study Notes
Reovirus and Rotavirus
- Reovirus has 11 segments of double-stranded RNA.
- Rotavirus replicates in the cytoplasm and has a naked capsid with 3 layers.
- Rotavirus is a double-stranded RNA virus with 11 segments.
Rotavirus Infection
- Rotavirus infects enterocytes in the villi of the small intestine.
- Damaged enterocytes release the virus into the lumen.
- Infection is usually self-limiting and resolves in 3-7 days.
Clinical Features
- Rotavirus causes toxic-mediated secretory diarrhea.
- NSP4 causes secretory diarrhea.
- Chloride permeability is increased, leading to diarrhea.
Epidemiology
- Rotavirus is a major etiology of infantile gastroenteritis worldwide.
- Children are the population most at risk, especially those in daycare.
Prevention and Treatment
- Treatment is supportive care and oral rehydration therapy.
- Live attenuated oral vaccine is available.
- The first dose should be given before 3 months of age to ensure efficacy and reduce the risk of intussusception.
Reovirus and Rotavirus
- Reovirus has 11 segments of double-stranded RNA.
- Rotavirus replicates in the cytoplasm and has a naked capsid with 3 layers.
- Rotavirus is a double-stranded RNA virus with 11 segments.
Rotavirus Infection
- Rotavirus infects enterocytes in the villi of the small intestine.
- Damaged enterocytes release the virus into the lumen.
- Infection is usually self-limiting and resolves in 3-7 days.
Clinical Features
- Rotavirus causes toxic-mediated secretory diarrhea.
- NSP4 causes secretory diarrhea.
- Chloride permeability is increased, leading to diarrhea.
Epidemiology
- Rotavirus is a major etiology of infantile gastroenteritis worldwide.
- Children are the population most at risk, especially those in daycare.
Prevention and Treatment
- Treatment is supportive care and oral rehydration therapy.
- Live attenuated oral vaccine is available.
- The first dose should be given before 3 months of age to ensure efficacy and reduce the risk of intussusception.
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Description
This quiz covers the structure and replication of Rotavirus and Reovirus, as well as the clinical features of Rotavirus infection. Learn about the characteristics of these viruses and how they infect the small intestine.
