Rosalind Franklin and Photograph 51

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Questions and Answers

What was the significance of Photograph 51 in the field of science?

  • It provided the first clear image of DNA's crystalline structure. (correct)
  • It showed the three-dimensional structure of proteins.
  • It was the first image of the entire human genome.
  • It depicted the structure of a tobacco mosaic virus.

Which statement accurately describes Rosalind Franklin's contributions?

  • She refined X-ray techniques to produce the first clear images of DNA. (correct)
  • She identified the polio virus structure using X-ray techniques.
  • She was awarded a Nobel Prize for her work on DNA.
  • She discovered the first living cells under a microscope.

What did Rosalind Franklin propose about the structure of DNA?

  • That the DNA backbone lies on the inside of the molecule.
  • That it is a helix composed of two strands. (correct)
  • That it is a linear molecule with a single strand.
  • That it consists of three strands in a triangular formation.

Which part of Rosalind Franklin's career involved studying viruses?

<p>At Birkbeck College, London, after her work on DNA. (A)</p> Signup and view all the answers

Why was Rosalind Franklin not eligible for the Nobel Prize awarded in 1962?

<p>She passed away before the announcement of the prize. (B)</p> Signup and view all the answers

What significant discovery about DNA's structure did Rosalind Franklin make from Photograph 51?

<p>DNA has a helical structure with two strands. (A)</p> Signup and view all the answers

What role did Maurice Wilkins play in Rosalind Franklin's research process?

<p>He took over DNA research techniques after Franklin established them. (B)</p> Signup and view all the answers

Which virus model did Rosalind Franklin develop successfully after her work on DNA?

<p>The tobacco mosaic virus (TMV) model. (C)</p> Signup and view all the answers

How did Franklin's contribution to DNA research become widely recognized?

<p>Wilkins shared Photograph 51 with Watson and Crick without crediting her. (C)</p> Signup and view all the answers

In what year did Franklin produce the groundbreaking Photograph 51?

<p>1952 (C)</p> Signup and view all the answers

What primary technique did Rosalind Franklin utilize to contribute to the understanding of DNA structure?

<p>X-ray crystallography (B)</p> Signup and view all the answers

In which year did Rosalind Franklin produce the first sharp image of crystalline DNA?

<p>1952 (B)</p> Signup and view all the answers

What was Rosalind Franklin's academic degree from the University of Cambridge?

<p>Degree in physical chemistry (A)</p> Signup and view all the answers

Which statement best describes the recognition of Rosalind Franklin's work during her lifetime?

<p>Her work was largely overlooked. (C)</p> Signup and view all the answers

What notable comment did Rosalind Franklin make regarding the relationship between science and everyday life?

<p>Science and everyday life cannot and should not be separated. (C)</p> Signup and view all the answers

What significant project did Maurice Wilkins contribute to during World War II?

<p>The Manhattan Project (B)</p> Signup and view all the answers

With whom did Maurice Wilkins share the Nobel Prize in Physiology or Medicine in 1962?

<p>James Watson and Francis Crick (D)</p> Signup and view all the answers

What was the primary technique used by Wilkins to study DNA fibers?

<p>X-ray imaging (A)</p> Signup and view all the answers

What was the total amount of grants received by Maurice Wilkins as mentioned in the content?

<p>$13,000 and $4,000 (B)</p> Signup and view all the answers

What role did Maurice Wilkins assume in 1970 at King's College, London?

<p>Director of the biophysics unit (A)</p> Signup and view all the answers

Flashcards

Who was Rosalind Franklin?

Rosalind Franklin was a British chemist whose groundbreaking work in X-ray crystallography was crucial to the discovery of the DNA structure.

What was Franklin's key contribution to DNA research?

Franklin's expertise in X-ray crystallography allowed her to capture detailed images of DNA's structure, revealing its characteristic double helix shape.

What significant image did Franklin capture?

In 1952, Franklin produced the first clear image of crystalline DNA using X-ray diffraction techniques. This image was instrumental in helping Watson and Crick build their DNA model.

Why is Franklin's story a reminder of the challenges faced by women in science?

While Franklin's work was instrumental in determining the structure of DNA, she received limited recognition during her lifetime. She was only 37 when she died in 1958.

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What were some of Franklin's early research interests?

Franklin's research on the chemical structure of coal and graphite demonstrated her early aptitude for scientific investigation. This work earned her a doctorate from Cambridge University.

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Photograph 51

A groundbreaking image captured by Rosalind Franklin in 1952 using X-ray diffraction, showing the helical structure of DNA.

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X-ray Diffraction

The process of using X-rays to analyze the internal structure of crystals, revealing the arrangement of atoms within a molecule.

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Rosalind Franklin

A scientist who made significant contributions to the understanding of the structure of DNA using X-ray diffraction techniques and whose work was crucial in developing the double helix model.

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Double Helix

The shape of DNA, characterized by two strands twisted around each other like a ladder.

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Polio Virus

A type of virus that affects the nervous system and can cause paralysis.

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What was Photograph 51?

An X-ray image of DNA taken by Rosalind Franklin that revealed the double helical structure. It was a crucial piece of evidence for Watson and Crick.

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What key information did Franklin's image of DNA reveal?

Rosalind Franklin's groundbreaking image of DNA's structure revealed its characteristic spiral shape, composed of two strands.

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What significance did Franklin's work have on understanding DNA's structure?

Franklin's research at King's College London, focusing on DNA structure, revealed a significant aspect of the molecule's arrangement. She determined that the 'backbone' of DNA lies on the outside of the structure.

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How was Rosalind Franklin treated for her contributions to scientists' understanding of DNA?

Franklin's scientific contributions to understanding DNA's structure were not fully acknowledged during her lifetime despite playing a crucial role in Watson and Crick's groundbreaking discovery.

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What were some of Franklin's other research areas?

Rosalind Franklin's expertise in crystallography extended beyond DNA, leading to her discoveries about vital structures like the tobacco mosaic virus (TMV).

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Who was Maurice Wilkins?

Maurice Wilkins was a biophysicist who shared the Nobel Prize in Physiology or Medicine with Francis Crick and James Watson for their discovery of the DNA structure. He studied the structure of DNA using X-ray diffraction, which helped determine its double helix shape.

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What was Wilkins's research method?

Wilkins's work focused on using X-ray diffraction to study DNA fibers. This technique allowed him to obtain images that showed the intricate structure of DNA, leading to the understanding of its double helix shape.

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Who did Wilkins work with to study DNA?

Wilkins worked with Rosalind Franklin at King's College London, where their combined efforts produced crucial X-ray images of DNA. These images, particularly one known as 'Photograph 51,' were instrumental in understanding the double helix structure.

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Why is Wilkins's contribution to DNA discovery often overlooked?

While Wilkins's work was essential in determining the DNA structure, his contribution is often overshadowed by those of Watson and Crick. The X-ray images he obtained were instrumental in the discovery, yet he received less recognition compared to his colleagues.

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What other areas did Wilkins research?

Besides studying DNA, Wilkins also conducted research on the polio virus and received grants to support his scientific endeavors. His work demonstrated a commitment to uncovering the secrets of various biological systems.

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