Rosalind Franklin and DNA X-Ray Photography

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Questions and Answers

What was the significance of Photograph 51?

  • It was the first photograph of DNA ever taken.
  • It disproved the existence of DNA.
  • It revealed the helical structure of DNA. (correct)
  • It showed the triple helix model of DNA.

What did Franklin propose about the structure of DNA?

  • The backbone lay on the outside of the molecule. (correct)
  • The backbone was made of proteins.
  • The DNA molecule was a single strand.
  • The DNA strands were parallel.

Who was shown Photograph 51 without Franklin's knowledge?

  • Francis Crick and James Watson (correct)
  • Alexander Todd
  • J. D. Bernal
  • Linus Pauling

In what year was the model of the DNA structure published by Crick and Watson?

<p>1953 (B)</p> Signup and view all the answers

Where did Franklin move to in 1953, and what did she study there?

<p>Birkbeck College; crystalline structure of viruses (C)</p> Signup and view all the answers

With which virus did Franklin achieve a groundbreaking modeling success using her crystallography skills?

<p>Tobacco Mosaic Virus (TMV) (C)</p> Signup and view all the answers

What was one of the critical outcomes of Franklin’s X-ray research at King’s College?

<p>Contradiction of previous beliefs about DNA’s structure (C)</p> Signup and view all the answers

Flashcards

Photograph 51

The first clear image of DNA's crystalline structure, taken by Rosalind Franklin.

Rosalind Franklin

Scientist who produced Photograph 51 and contributed to DNA research.

DNA structure

DNA is composed of two helical strands, forming a double helix.

Maurice Wilkins

Former leader who shared Photograph 51 with Crick and Watson without Franklin's consent.

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Double helix model

The structure of DNA consisting of two intertwined strands.

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Tobacco Mosaic Virus (TMV)

A virus studied by Franklin, for which she proposed a new molecular model.

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Crystallography

A technique used by Franklin to study the structure of molecules.

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Study Notes

DNA X-Ray Photography

  • Photograph 51 captured the first clear image of DNA's crystalline structure, a significant scientific achievement.
  • Rosalind Franklin took the photograph, a crucial element in understanding DNA's structure.
  • Franklin's X-ray diffraction image revealed DNA's helical structure, consisting of two strands.
  • Franklin also proposed that the DNA backbone lay on the outside of the molecule.
  • Other researchers, without Franklin's knowledge, utilized her data to construct their own model of DNA.
  • James Watson and Francis Crick, independently, used Franklin's data to develop their double helix model of DNA.
  • Although Franklin's contributions were key, her crucial role was not fully recognized at the time.
  • Franklin shifted her focus from studying DNA, to the structure of Tobacco Mosaic Virus (TMV).

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