Podcast
Questions and Answers
What crucial piece of information did Photograph 51 reveal about the structure of DNA?
What crucial piece of information did Photograph 51 reveal about the structure of DNA?
- It demonstrated that DNA had a triple helix structure.
- It showed that the backbone of the DNA molecule was on the interior.
- It revealed the precise sequence of base pairs in DNA.
- It confirmed the helical structure and double-stranded nature of DNA. (correct)
What was Rosalind Franklin's key contribution to understanding DNA?
What was Rosalind Franklin's key contribution to understanding DNA?
- Building the first 3D model of DNA.
- Identifying the specific base pairing rules in DNA.
- Developing the theoretical framework for DNA replication.
- Capturing Photograph 51, which revealed the helical structure of DNA. (correct)
How was Maurice Wilkins involved in the discovery of DNA's structure?
How was Maurice Wilkins involved in the discovery of DNA's structure?
- He collaborated with Franklin, but shared her work without her knowledge. (correct)
- He developed the X-ray diffraction techniques used by Franklin.
- He played a primary role in interpreting Photograph 51 and deducing the double helix.
- He independently confirmed Franklin's findings using different methods.
What was the primary contribution of Watson and Crick to the understanding of DNA?
What was the primary contribution of Watson and Crick to the understanding of DNA?
In what year did Watson and Crick publish their DNA model?
In what year did Watson and Crick publish their DNA model?
What significant event related to DNA research occurred in 1958?
What significant event related to DNA research occurred in 1958?
What was Rosalind Franklin's area of expertise?
What was Rosalind Franklin's area of expertise?
Which scientist received a Nobel Prize for research on DNA structure?
Which scientist received a Nobel Prize for research on DNA structure?
What did Franklin focus on after her work at King's College?
What did Franklin focus on after her work at King's College?
When was the crystalline structure of the polio virus confirmed?
When was the crystalline structure of the polio virus confirmed?
Flashcards
Photograph 51
Photograph 51
The first clear image of the DNA structure taken by Rosalind Franklin using X-ray diffraction.
Rosalind Franklin
Rosalind Franklin
Key scientist who produced Photograph 51, revealing DNA's helical structure.
Helical structure
Helical structure
The spiral shape of DNA, identified through X-ray techniques.
DNA backbone
DNA backbone
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James Watson & Francis Crick
James Watson & Francis Crick
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Maurice Wilkins
Maurice Wilkins
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1952
1952
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Nobel Prize
Nobel Prize
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Tobacco mosaic virus
Tobacco mosaic virus
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Significance of Franklin's work
Significance of Franklin's work
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Study Notes
X-Ray Photographs of DNA
- Photograph 51, taken in 1952, was the first clear image of DNA's crystalline structure
- This image revealed DNA's helical (spiral) structure, composed of two strands
- The photograph was taken by Rosalind Franklin
- It took 60 hours to produce the X-ray image
- Franklin's work was crucial in determining DNA's structure, but her contributions were not immediately recognized
Rosalind Franklin's Contributions
- Franklin refined X-ray techniques, leading to the clear image of DNA
- She proposed that DNA's backbone lay outside the molecule
- Her work on viruses, like the tobacco mosaic virus (TMV), demonstrated her skills in crystallography
- She shifted to studying virus structure after 1953 at Birkbeck College
Maurice Wilkins
- Wilkins shared a Nobel Prize for the work on DNA structure, along with Crick and Watson
- Wilkins used X-ray imaging to study DNA structure
- He later became a professor at King's College
Funding and Recognition
- Rosalind Franklin received a grant of $13,000 to study the polio virus
- She bequeathed $4,000 to a colleague (Aaron Klug)
- Franklin's contributions were essential yet were not appropriately recognized during her lifetime
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