Rosalind Franklin and DNA Structure
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Questions and Answers

Rosalind Franklin's expertise in which of the following fields was instrumental in her contribution to understanding DNA's structure?

  • Biochemistry and molecular biology
  • X-ray crystallography (correct)
  • Organic chemistry and synthesis
  • Genetics and molecular cloning

Which of the following best describes the approach to biophysics pioneered at King's College, London, in 1951, where Franklin worked?

  • Using physics to study biological molecules (correct)
  • Applying engineering principles to develop medical devices
  • Using advanced mathematics to model biological systems
  • Combining chemistry and biology to synthesize new drugs

In what year did Rosalind Franklin produce the first sharp image of crystalline DNA, a breakthrough that revealed its double helix shape?

  • 1952 (correct)
  • 1954
  • 1951
  • 1953

What was significance of Franklin's move to Birkbeck College in 1953?

<p>She shifted her focus to groundbreaking studies on major crop viruses (D)</p> Signup and view all the answers

Rosalind Franklin's initial research post after graduating from Cambridge in 1941 involved studying the chemical structure of which substances?

<p>Coal and graphite (C)</p> Signup and view all the answers

Which of the following statements best reflects the sentiment towards Rosalind Franklin's role in the discovery of DNA's structure during her lifetime?

<p>Her work was vital but largely overlooked. (A)</p> Signup and view all the answers

What critical expertise did Rosalind Franklin develop in Paris, beginning in 1947, which later proved vital to her DNA research?

<p>X-ray crystallography (B)</p> Signup and view all the answers

What factor most strongly influenced Rosalind Franklin's ability to make crucial contributions to understanding one of the 20th century's biggest scientific questions?

<p>Her specialized expertise in X-ray diffraction techniques (A)</p> Signup and view all the answers

What was Maurice Wilkins' role at King's College when Rosalind Franklin was asked to head X-ray research in 1951?

<p>He was the post-holder whose knowledge was bypassed when Franklin was appointed. (C)</p> Signup and view all the answers

According to Rosalind Franklin's quote, what is the relationship between science and everyday life?

<p>Science and everyday life should be integrated (A)</p> Signup and view all the answers

Flashcards

Who was Rosalind Franklin?

British chemist whose work revealed the structure of DNA

What is X-ray crystallography?

Using X-rays to examine a substance's crystalline form and molecular structure.

What was the 'DNA race'?

The race among scientists to discover the molecular structure of DNA.

Franklin at King's College, London?

She began photographing DNA strands, pioneering biophysics, using physics to study biological molecules.

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What is BCURA?

Association Rosalind became a researcher for in 1942

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Franklin's DNA Breakthrough?

Produced in 1952; revealed DNA's double helix shape.

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Franklin's Pioneering Work?

studies into major crop viruses.

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Study Notes

  • Rosalind Franklin was a British chemist.
  • Her work was vital to discovering the structure of DNA.
  • Her work was largely overlooked in her lifetime.
  • Born in London in 1920.
  • Graduated from Cambridge University in 1941 with a degree in physical chemistry.
  • Took a research post studying the chemical structure of coal and graphite.
  • Earned her doctorate from Cambridge in 1945.
  • Moved to Paris in 1947.
  • Studied X-ray crystallography, using X-rays to examine the crystalline form of substances.
  • Determined the molecular structure.
  • Her expertise enabled her to make a crucial contribution to one of the biggest scientific conundrums of the 20th century.
  • During the 1950s, a number of scientists were in a "race" to discover the molecular structure of DNA, the chemical found inside all living things and encodes genetic information
  • In 1951, James Watson and Francis Crick were attempting to do the same thing as Franklin in Cambridge
  • In 1951, Franklin began photographing strands of DNA at King's College, London.
  • A group of physicists, biologists, and biochemists were helping pioneer biophysics, using physics to study biological molecules at King's College

Milestones

  • 1942: Became a researcher for BCURA, the British Coal Utilization Research Association.
  • 1947: Trained under French engineer Jacques Mering and became an X-ray crystallographer.
  • 1951: Asked to head X-ray research at King's College, London, without the knowledge of post-holder Maurice Wilkins.
  • 1952: Produced the first sharp image of crystalline DNA, which revealed its double helix shape.
  • 1953: Moved to Birkbeck College, London, and led groundbreaking studies into major crop viruses.
  • "Science and everyday life cannot and should not be separated." - Rosalind Franklin, 1940

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Learn about Rosalind Franklin, a British chemist. Her work was vital to discovering the structure of DNA, but it was largely overlooked in her lifetime. She Studied X-ray crystallography and contributed to understanding DNA.

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