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DNA Structure and Function: Watson and Crick Model

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DNA Structure and Function: Watson and Crick Model

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Questions and Answers

Who proposed the structure of DNA that included two chains of nucleotides spiraling around each other in a pair of right-handed helices?

Watson and Crick

What was the erroneous proposal by Linus Pauling regarding the composition of DNA?

Linus Pauling suggested that DNA was composed of three nucleotide strands.

In a right-handed helix, which direction does each strand follow as observed from the central axis of the molecule?

Clockwise path

How are the two chains comprising one double helix oriented in relation to each other?

Antiparallel Signup and view all the answers

Where is the -sugar-phosphate-sugar-phosphate- backbone located within the DNA molecule?

On the outside Signup and view all the answers

What gives the DNA molecule a large negative charge?

Phosphate groups Signup and view all the answers

What are the forces that provide stability for the entire DNA molecule?

Hydrophobic interactions and van der Waals forces Signup and view all the answers

How are the two strands of DNA held together?

By hydrogen bonds between each base of one strand and an associated base on the other strand Signup and view all the answers

What is the width of the DNA double helix?

2 nm Signup and view all the answers

What is the specific pairing rule between pyrimidines and purines in DNA?

A pyrimidine in one chain is always paired with a purine in the other chain Signup and view all the answers

Why are adenine and thymine, as well as guanine and cytosine, the only possible base pairs in DNA?

Due to structural restrictions on the configurations of the bases Signup and view all the answers

What was the result of Chargaff's base composition analysis that was communicated to Watson and Crick?

A-T and G-C are the only possible base pairs in DNA Signup and view all the answers