RNA Primers and DNA Replication
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Questions and Answers

Which process involves the separation of sister chromatids during cell division?

  • Mitosis (correct)
  • DNA repair
  • Cytokinesis
  • DNA replication

    • When does DNA synthesis occur during the cell cycle?

  • Cytokinesis
  • S phase (correct)
  • Interphase
  • M phase

    • What is the main purpose of DNA replication?

  • To distribute chromosomes to daughter cells
  • To repair damage to genetic material
  • To form new nuclear envelopes
  • To accurately reproduce genetic material (correct)

    • Which DNA polymerase is responsible for synthesizing the leading strand during DNA replication?

    <p>DNA polymerase III</p> Signup and view all the answers

    What is the function of the sliding clamp during DNA replication?

    <p>To stabilize the DNA polymerase</p> Signup and view all the answers

    Which enzyme is responsible for removing the RNA primer during DNA replication in eukaryotes?

    <p>FEN1</p> Signup and view all the answers

    Which enzyme is responsible for unwinding the DNA strands during replication in bacteria?

    <p>DnaB</p> Signup and view all the answers

    What is the name of the replication origin in budding yeast (Saccharomyces cerevisiae)?

    <p>Autonomously replicating sequence (ARS)</p> Signup and view all the answers

    What is the directionality of DNA synthesis during replication?

    <p>5' -&gt; 3'</p> Signup and view all the answers

    Which DNA polymerase is primarily responsible for DNA replication in cells?

    <p>DNA polymerase III</p> Signup and view all the answers

    Which model of DNA replication suggests that the parent molecule is intact and a second, completely new copy is made?

    <p>Conservative model</p> Signup and view all the answers

    Which model of DNA replication suggests that each strand of the double helix is a mixture of old and newly synthesized segments?

    <p>Dispersive model</p> Signup and view all the answers

    What did Matthew Meselson and Franklin Stahl demonstrate about DNA replication?

    <p>DNA replication is semiconservative</p> Signup and view all the answers

    In eukaryotes, replication of linear chromosomes is initiated at multiple sites, creating replication units called ____.

    <p>Replicons</p> Signup and view all the answers

    Which direction does DNA polymerase synthesize the leading strand?

    <p>5' -&gt; 3'</p> Signup and view all the answers

    What are the short fragments called that make up the lagging strand during DNA replication?

    <p>Okazaki fragments</p> Signup and view all the answers

    What is the role of DNA ligase in DNA replication?

    <p>Join Okazaki fragments</p> Signup and view all the answers

    Which enzyme is responsible for DNA replication in bacteria?

    <p>DNA polymerase III</p> Signup and view all the answers

    Which enzyme is responsible for proofreading DNA during replication?

    <p>Exonuclease</p> Signup and view all the answers

    What is the main function of DNA polymerase I in bacteria?

    <p>Removal and replacement of RNA primers</p> Signup and view all the answers

    Which DNA polymerase is responsible for nuclear DNA synthesis in eukaryotes?

    <p>DNA polymerase α</p> Signup and view all the answers

    What is the main function of telomerase in eukaryotes?

    <p>DNA synthesis</p> Signup and view all the answers

    Which enzyme is responsible for unwinding the DNA during replication in E. coli?

    <p>DNA helicase</p> Signup and view all the answers

    Which protein keeps the DNA unwound and accessible to the replication machinery?

    <p>Single-stranded DNA binding protein (SSB)</p> Signup and view all the answers

    What is the role of DNA ligase in DNA replication?

    <p>Joining adjacent DNA fragments</p> Signup and view all the answers

    What is the function of the replisome in DNA replication?

    <p>Coordinating DNA unwinding and synthesis</p> Signup and view all the answers

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