32 Questions
Which medication is classified as second-line treatment for Multiple Sclerosis?
Fingolimod (Gilenya)
What is the primary treatment for cognitive decline in Multiple Sclerosis?
Acetylcholinesterase inhibitors
Which medication is used to treat hypo-reflexic bladder in Multiple Sclerosis?
Bethanechol
What is the first-line treatment for depression associated with Multiple Sclerosis?
SSRI
Which medication should a patient with Acute Exacerbations of Multiple Sclerosis NOT be discharged on?
Methylprednisolone
What is the primary treatment for fatigue in Multiple Sclerosis?
Amantadine
Which antifungal medication has a safer drug-drug interaction profile and requires renal dose adjustment?
Fluconazole
What is a common adverse effect associated with Voriconazole?
Hepatotoxicity
Which HIV medication class is associated with lactic acidosis as a toxicity?
Nucleoside/tide reverse transcriptase inhibitors (NRTIs)
Which antiretroviral medication is linked to an increased risk of myocardial infarction (MI)?
Abacavir (ABC)
Among Amphotericin B, Azole antifungals, and Echinocandins, which class is considered the most toxic?
Amphotericin B
Which antiretroviral medication is associated with an adverse effect known as Drug Hypersensitivity Syndrome (DST)?
Abacavir (ABC)
Which medication is indicated for primary progressive MS and relapsing-remitting MS?
Ocrelizumab
What pre-medication is recommended prior to infusion of Natalizumab (Tysabri)?
Antihistamine
Which oral agent for RRMS should be monitored for increased LFTs, infection, and CV adverse effects?
Fingolimod (Gilenya)
In which condition is Alemtuzumab (Lemtrada) indicated in the treatment of MS?
Relapsing forms of MS once failed 2 or more DMTs
Which medication requires monitoring for JC virus status both before starting and every 6 months during therapy?
Natalizumab (Tysabri)
What is the recommended pre-medication prior to administration of Interferon-beta for MS?
Steroid
What is the preferred initial non-biologic agent for mild rheumatoid arthritis?
Hydroxychloroquine
Which agent has a loading and maintenance dosing regimen?
Leflunomide
Which biologic agent is commonly used with methotrexate for rheumatoid arthritis treatment?
Golimumab
Which medication is indicated as 1st line for lupus nephritis?
Mycophenolate
Which medication is NOT typically used in lupus due to its teratogenic effects?
Prednisone
Which drug can cause bone marrow suppression, gastrointestinal upset, and malignancy in patients with lupus?
Azathioprine
Which agent is a calcineurin inhibitor used in solid organ transplant maintenance?
Cyclosporine
'Baseline' drug used to induce solid organ transplant immunosuppression when avoiding nephrotoxic agents:
Basalixumab
Which antiretroviral medication is associated with renal dysfunction and decreased bone mineral density?
Emtriva (emtricitabine/FTC)
Which class of antiretrovirals is known for causing fulminant hepatic failure and rash, especially with efavirenz?
Non-nucleoside Reverse Transcriptase Inhibitors
Which Protease Inhibitor should be combined with ritonavir or cobicistat and is associated with lipodystrophy as a long-term complication?
Reyataz (atazanavir/ATV)
Which antiretroviral medication has an increased risk of suicidality, especially in patients with existing psychiatric disease?
Sustiva (efavirenz/EFV)
Which Fusion Inhibitor is mentioned in the text for occupational exposures and prophylactic use?
Fuzeon (enfuviritide)
Which antiretroviral combination is approved by the FDA for daily dosing and recommended for PrEP?
*preferred regimens Truvada (TDF + emtricitabine)
Test your knowledge on oral agents for rheumatoid arthritis including Teriflunomide, Dimethyl Fumerate, and Hydroxychloroquine. Learn about initial preferences for mild disease, monitoring protocols, treatment onset, and failure criteria.
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