Rheumatoid Arthritis Oral Agents Quiz
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Questions and Answers

Which medication is classified as second-line treatment for Multiple Sclerosis?

  • Interferon beta (Rebif)
  • Fingolimod (Gilenya) (correct)
  • Dimethyl Fumerate (Tecfidera)
  • Glatiramer acetate (Copaxone)
  • What is the primary treatment for cognitive decline in Multiple Sclerosis?

  • Stimulants
  • Acetylcholinesterase inhibitors (correct)
  • Modafinil
  • Dextromethorphan
  • Which medication is used to treat hypo-reflexic bladder in Multiple Sclerosis?

  • Bethanechol (correct)
  • Dalfampridine
  • Baclofen
  • Gabapentin
  • What is the first-line treatment for depression associated with Multiple Sclerosis?

    <p>SSRI</p> Signup and view all the answers

    Which medication should a patient with Acute Exacerbations of Multiple Sclerosis NOT be discharged on?

    <p>Methylprednisolone</p> Signup and view all the answers

    What is the primary treatment for fatigue in Multiple Sclerosis?

    <p>Amantadine</p> Signup and view all the answers

    Which antifungal medication has a safer drug-drug interaction profile and requires renal dose adjustment?

    <p>Fluconazole</p> Signup and view all the answers

    What is a common adverse effect associated with Voriconazole?

    <p>Hepatotoxicity</p> Signup and view all the answers

    Which HIV medication class is associated with lactic acidosis as a toxicity?

    <p>Nucleoside/tide reverse transcriptase inhibitors (NRTIs)</p> Signup and view all the answers

    Which antiretroviral medication is linked to an increased risk of myocardial infarction (MI)?

    <p>Abacavir (ABC)</p> Signup and view all the answers

    Among Amphotericin B, Azole antifungals, and Echinocandins, which class is considered the most toxic?

    <p>Amphotericin B</p> Signup and view all the answers

    Which antiretroviral medication is associated with an adverse effect known as Drug Hypersensitivity Syndrome (DST)?

    <p>Abacavir (ABC)</p> Signup and view all the answers

    Which medication is indicated for primary progressive MS and relapsing-remitting MS?

    <p>Ocrelizumab</p> Signup and view all the answers

    What pre-medication is recommended prior to infusion of Natalizumab (Tysabri)?

    <p>Antihistamine</p> Signup and view all the answers

    Which oral agent for RRMS should be monitored for increased LFTs, infection, and CV adverse effects?

    <p>Fingolimod (Gilenya)</p> Signup and view all the answers

    In which condition is Alemtuzumab (Lemtrada) indicated in the treatment of MS?

    <p>Relapsing forms of MS once failed 2 or more DMTs</p> Signup and view all the answers

    Which medication requires monitoring for JC virus status both before starting and every 6 months during therapy?

    <p>Natalizumab (Tysabri)</p> Signup and view all the answers

    What is the recommended pre-medication prior to administration of Interferon-beta for MS?

    <p>Steroid</p> Signup and view all the answers

    What is the preferred initial non-biologic agent for mild rheumatoid arthritis?

    <p>Hydroxychloroquine</p> Signup and view all the answers

    Which agent has a loading and maintenance dosing regimen?

    <p>Leflunomide</p> Signup and view all the answers

    Which biologic agent is commonly used with methotrexate for rheumatoid arthritis treatment?

    <p>Golimumab</p> Signup and view all the answers

    Which medication is indicated as 1st line for lupus nephritis?

    <p>Mycophenolate</p> Signup and view all the answers

    Which medication is NOT typically used in lupus due to its teratogenic effects?

    <p>Prednisone</p> Signup and view all the answers

    Which drug can cause bone marrow suppression, gastrointestinal upset, and malignancy in patients with lupus?

    <p>Azathioprine</p> Signup and view all the answers

    Which agent is a calcineurin inhibitor used in solid organ transplant maintenance?

    <p>Cyclosporine</p> Signup and view all the answers

    'Baseline' drug used to induce solid organ transplant immunosuppression when avoiding nephrotoxic agents:

    <p>Basalixumab</p> Signup and view all the answers

    Which antiretroviral medication is associated with renal dysfunction and decreased bone mineral density?

    <p>Emtriva (emtricitabine/FTC)</p> Signup and view all the answers

    Which class of antiretrovirals is known for causing fulminant hepatic failure and rash, especially with efavirenz?

    <p>Non-nucleoside Reverse Transcriptase Inhibitors</p> Signup and view all the answers

    Which Protease Inhibitor should be combined with ritonavir or cobicistat and is associated with lipodystrophy as a long-term complication?

    <p>Reyataz (atazanavir/ATV)</p> Signup and view all the answers

    Which antiretroviral medication has an increased risk of suicidality, especially in patients with existing psychiatric disease?

    <p>Sustiva (efavirenz/EFV)</p> Signup and view all the answers

    Which Fusion Inhibitor is mentioned in the text for occupational exposures and prophylactic use?

    <p>Fuzeon (enfuviritide)</p> Signup and view all the answers

    Which antiretroviral combination is approved by the FDA for daily dosing and recommended for PrEP?

    <p>*preferred regimens Truvada (TDF + emtricitabine)</p> Signup and view all the answers

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