Rheumatoid Arthritis Oral Agents Quiz

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Questions and Answers

Which medication is classified as second-line treatment for Multiple Sclerosis?

  • Interferon beta (Rebif)
  • Fingolimod (Gilenya) (correct)
  • Dimethyl Fumerate (Tecfidera)
  • Glatiramer acetate (Copaxone)

What is the primary treatment for cognitive decline in Multiple Sclerosis?

  • Stimulants
  • Acetylcholinesterase inhibitors (correct)
  • Modafinil
  • Dextromethorphan

Which medication is used to treat hypo-reflexic bladder in Multiple Sclerosis?

  • Bethanechol (correct)
  • Dalfampridine
  • Baclofen
  • Gabapentin

What is the first-line treatment for depression associated with Multiple Sclerosis?

<p>SSRI (B)</p> Signup and view all the answers

Which medication should a patient with Acute Exacerbations of Multiple Sclerosis NOT be discharged on?

<p>Methylprednisolone (B)</p> Signup and view all the answers

What is the primary treatment for fatigue in Multiple Sclerosis?

<p>Amantadine (B)</p> Signup and view all the answers

Which antifungal medication has a safer drug-drug interaction profile and requires renal dose adjustment?

<p>Fluconazole (A)</p> Signup and view all the answers

What is a common adverse effect associated with Voriconazole?

<p>Hepatotoxicity (C)</p> Signup and view all the answers

Which HIV medication class is associated with lactic acidosis as a toxicity?

<p>Nucleoside/tide reverse transcriptase inhibitors (NRTIs) (B)</p> Signup and view all the answers

Which antiretroviral medication is linked to an increased risk of myocardial infarction (MI)?

<p>Abacavir (ABC) (D)</p> Signup and view all the answers

Among Amphotericin B, Azole antifungals, and Echinocandins, which class is considered the most toxic?

<p>Amphotericin B (D)</p> Signup and view all the answers

Which antiretroviral medication is associated with an adverse effect known as Drug Hypersensitivity Syndrome (DST)?

<p>Abacavir (ABC) (A)</p> Signup and view all the answers

Which medication is indicated for primary progressive MS and relapsing-remitting MS?

<p>Ocrelizumab (B)</p> Signup and view all the answers

What pre-medication is recommended prior to infusion of Natalizumab (Tysabri)?

<p>Antihistamine (D)</p> Signup and view all the answers

Which oral agent for RRMS should be monitored for increased LFTs, infection, and CV adverse effects?

<p>Fingolimod (Gilenya) (A)</p> Signup and view all the answers

In which condition is Alemtuzumab (Lemtrada) indicated in the treatment of MS?

<p>Relapsing forms of MS once failed 2 or more DMTs (A)</p> Signup and view all the answers

Which medication requires monitoring for JC virus status both before starting and every 6 months during therapy?

<p>Natalizumab (Tysabri) (D)</p> Signup and view all the answers

What is the recommended pre-medication prior to administration of Interferon-beta for MS?

<p>Steroid (B)</p> Signup and view all the answers

What is the preferred initial non-biologic agent for mild rheumatoid arthritis?

<p>Hydroxychloroquine (D)</p> Signup and view all the answers

Which agent has a loading and maintenance dosing regimen?

<p>Leflunomide (D)</p> Signup and view all the answers

Which biologic agent is commonly used with methotrexate for rheumatoid arthritis treatment?

<p>Golimumab (C)</p> Signup and view all the answers

Which medication is indicated as 1st line for lupus nephritis?

<p>Mycophenolate (D)</p> Signup and view all the answers

Which medication is NOT typically used in lupus due to its teratogenic effects?

<p>Prednisone (D)</p> Signup and view all the answers

Which drug can cause bone marrow suppression, gastrointestinal upset, and malignancy in patients with lupus?

<p>Azathioprine (A)</p> Signup and view all the answers

Which agent is a calcineurin inhibitor used in solid organ transplant maintenance?

<p>Cyclosporine (A)</p> Signup and view all the answers

'Baseline' drug used to induce solid organ transplant immunosuppression when avoiding nephrotoxic agents:

<p>Basalixumab (C)</p> Signup and view all the answers

Which antiretroviral medication is associated with renal dysfunction and decreased bone mineral density?

<p>Emtriva (emtricitabine/FTC) (C)</p> Signup and view all the answers

Which class of antiretrovirals is known for causing fulminant hepatic failure and rash, especially with efavirenz?

<p>Non-nucleoside Reverse Transcriptase Inhibitors (D)</p> Signup and view all the answers

Which Protease Inhibitor should be combined with ritonavir or cobicistat and is associated with lipodystrophy as a long-term complication?

<p>Reyataz (atazanavir/ATV) (D)</p> Signup and view all the answers

Which antiretroviral medication has an increased risk of suicidality, especially in patients with existing psychiatric disease?

<p>Sustiva (efavirenz/EFV) (B)</p> Signup and view all the answers

Which Fusion Inhibitor is mentioned in the text for occupational exposures and prophylactic use?

<p>Fuzeon (enfuviritide) (C)</p> Signup and view all the answers

Which antiretroviral combination is approved by the FDA for daily dosing and recommended for PrEP?

<p>*preferred regimens Truvada (TDF + emtricitabine) (D)</p> Signup and view all the answers

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