Rheumatoid Arthritis Oral Agents Quiz
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Questions and Answers

What is the first-line treatment for Multiple Sclerosis (MS) that falls under the category of oral medications?

  • Dimethyl Fumerate (Tecfidera) (correct)
  • Gabapentin
  • Ocrelizumab
  • Baclofen

Which medication is commonly used to manage cognitive decline in patients with MS?

  • Donepezil (correct)
  • Pregabalin
  • Amantadine
  • Dalfampridine

What is the primary treatment recommended for bowel and bladder dysfunction in MS patients with a hyper-reflexic bladder?

  • Fiber supplements
  • Fingolimod
  • Tizanidine
  • Cholinergic agents (correct)

Which medication is indicated for managing spasticity and gait issues in MS patients?

<p>Baclofen (D)</p> Signup and view all the answers

What is the tertiary treatment option for Pseudobulbar Palsy in MS patients?

<p>Dextromethorphan/quinidine (C)</p> Signup and view all the answers

Which medication is commonly used to address fatigue in MS patients?

<p>Modafinil (C)</p> Signup and view all the answers

If a patient with MS experiences acute exacerbations of focal neurologic disturbance lasting more than 24 hours, what is the recommended treatment?

<p>Methylprednisolone (C)</p> Signup and view all the answers

What is the primary treatment for UTIs caused by E. coli in patients with MS?

<p>Bactrim x5-7 days (B)</p> Signup and view all the answers

What is the recommended pre-medication regimen for Natalizumab (Tysabri) IV infusion?

<p>Methylprednisolone + Antihistamine + APAP (D)</p> Signup and view all the answers

Which type of MS is Ocrelizumab (Ocrevus) IV primarily used for?

<p>Relapsing forms of MS (A)</p> Signup and view all the answers

What is a common adverse drug reaction (ADR) associated with Alemtuzumab (Lemtrada)?

<p>Hypothyroidism (C)</p> Signup and view all the answers

Which medication requires monitoring for JC virus prior to and during therapy?

<p>Natalizumab (Tysabri) (D)</p> Signup and view all the answers

Which class of medications is typically used for more severe/progressive forms of MS with less frequent injections?

<p>Second-Generation Injectables (A)</p> Signup and view all the answers

What is a common side effect associated with Fingolimod (Gilenya) and similar oral agents?

<p>Increased liver function tests (LFTs) (B)</p> Signup and view all the answers

Which medication is a common monotherapy for RRMS in patients unresponsive to other therapies?

<p>Natalizumab (Tysabri) (C)</p> Signup and view all the answers

What is a key adverse effect that necessitates close monitoring with Mitoxantrone (Novantrone)?

<p>Cardiac toxicity (B)</p> Signup and view all the answers

What is the preferred initial non-biologic agent for mild Rheumatoid Arthritis?

<p>Hydroxychloroquine (B)</p> Signup and view all the answers

Which biologic agent is paired with Methotrexate for administration via IV infusion?

<p>Infliximab (A)</p> Signup and view all the answers

Which class of medication is NOT recommended to be added immediately after surgery due to its impact on healing?

<p>mTOR inhibitors (A)</p> Signup and view all the answers

What is the ADR most commonly associated with Calcineurin Inhibitors like Tacrolimus and Cyclosporine?

<p>Nephrotoxicity (C)</p> Signup and view all the answers

Which medication is often used for prophylaxis against Pneumocystis jirovecii pneumonia (PJP) in patients at risk?

<p>Trimethoprim/sulfamethoxazole (C)</p> Signup and view all the answers

Which medication is the drug of choice for prophylaxis against cytomegalovirus (CMV) in transplant recipients?

<p>Valganciclovir (B)</p> Signup and view all the answers

What is the common treatment regimen for invasive candidiasis?

<p>Echinocandins (D)</p> Signup and view all the answers

What is the preferred non-biologic agent for treatment of cutaneous lupus if topical treatments fail?

<p>Retinoids (B)</p> Signup and view all the answers

Which antifungal medication requires renal dose adjustment for use in urinary tract infections?

<p>Fluconazole (C)</p> Signup and view all the answers

What is the most common adverse effect associated with Flucytosine?

<p>Myelosuppression (C)</p> Signup and view all the answers

Which antifungal medication has the highest toxicity level among Amphotericin B, Azoles, and Echinocandins?

<p>Amphotericin B (D)</p> Signup and view all the answers

What is the recommended administration requirement for Posaconazole to ensure proper absorption?

<p>Take with food (C)</p> Signup and view all the answers

Which HIV medication is associated with the adverse effect of lactic acidosis?

<p>Zidovudine (AZT) (C)</p> Signup and view all the answers

Which antifungal medication may lead to long-term skin cancer if used extensively?

<p>Voriconazole (A)</p> Signup and view all the answers

Which HIV medication is associated with an increased risk of myocardial infarction (MI)?

<p>Ziagen (abacavir/ABC) (D)</p> Signup and view all the answers

Why is renal dose adjustment required for IV Voriconazole despite it being hepatically eliminated?

<p>'Toxic excipient in IV formulation which is cleared renally' (B)</p> Signup and view all the answers

Which class of antiretroviral drugs can lead to hepatotoxicity and an increased risk of suicidality?

<p>Non-nucleoside reverse transcriptase inhibitors (D)</p> Signup and view all the answers

What is a common side effect associated with the use of Tenofovir disoproxil (TDF)?

<p>Renal dysfunction (Fanconi’s syndrome) (A)</p> Signup and view all the answers

Which antiretroviral drug is known for causing lipodystrophy as a long-term complication?

<p>Reyataz (atazanavir/ATV) (C)</p> Signup and view all the answers

Which antiretroviral combination drug is approved for use in all populations?

<p>Truvada (TDF + emtricitabine) (D)</p> Signup and view all the answers

Which antiretroviral drug is associated with the complication of non-cirrhotic portal hypertension?

<p>Videx EC (didanosine/ddl) (A)</p> Signup and view all the answers

What is a common side effect of Non-nucleoside reverse transcriptase inhibitors like Sustiva (efavirenz/EFV)?

<p>Rash (A)</p> Signup and view all the answers

Which antiretroviral drug combination should be used with caution in patients with existing psychiatric disease due to its effects?

<p>Sustiva (efavirenz/EFV) + Viramune (nevirapine/NVP) (B)</p> Signup and view all the answers

'Biktarvy' is a combination drug that includes which of the following antiretroviral agents?

<p>*Biktarvy (bictegravir + emtricitabine + TAF) (A)</p> Signup and view all the answers

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