40 Questions
What is the first-line treatment for Multiple Sclerosis (MS) that falls under the category of oral medications?
Dimethyl Fumerate (Tecfidera)
Which medication is commonly used to manage cognitive decline in patients with MS?
Donepezil
What is the primary treatment recommended for bowel and bladder dysfunction in MS patients with a hyper-reflexic bladder?
Cholinergic agents
Which medication is indicated for managing spasticity and gait issues in MS patients?
Baclofen
What is the tertiary treatment option for Pseudobulbar Palsy in MS patients?
Dextromethorphan/quinidine
Which medication is commonly used to address fatigue in MS patients?
Modafinil
If a patient with MS experiences acute exacerbations of focal neurologic disturbance lasting more than 24 hours, what is the recommended treatment?
Methylprednisolone
What is the primary treatment for UTIs caused by E. coli in patients with MS?
Bactrim x5-7 days
What is the recommended pre-medication regimen for Natalizumab (Tysabri) IV infusion?
Methylprednisolone + Antihistamine + APAP
Which type of MS is Ocrelizumab (Ocrevus) IV primarily used for?
Relapsing forms of MS
What is a common adverse drug reaction (ADR) associated with Alemtuzumab (Lemtrada)?
Hypothyroidism
Which medication requires monitoring for JC virus prior to and during therapy?
Natalizumab (Tysabri)
Which class of medications is typically used for more severe/progressive forms of MS with less frequent injections?
Second-Generation Injectables
What is a common side effect associated with Fingolimod (Gilenya) and similar oral agents?
Increased liver function tests (LFTs)
Which medication is a common monotherapy for RRMS in patients unresponsive to other therapies?
Natalizumab (Tysabri)
What is a key adverse effect that necessitates close monitoring with Mitoxantrone (Novantrone)?
Cardiac toxicity
What is the preferred initial non-biologic agent for mild Rheumatoid Arthritis?
Hydroxychloroquine
Which biologic agent is paired with Methotrexate for administration via IV infusion?
Infliximab
Which class of medication is NOT recommended to be added immediately after surgery due to its impact on healing?
mTOR inhibitors
What is the ADR most commonly associated with Calcineurin Inhibitors like Tacrolimus and Cyclosporine?
Nephrotoxicity
Which medication is often used for prophylaxis against Pneumocystis jirovecii pneumonia (PJP) in patients at risk?
Trimethoprim/sulfamethoxazole
Which medication is the drug of choice for prophylaxis against cytomegalovirus (CMV) in transplant recipients?
Valganciclovir
What is the common treatment regimen for invasive candidiasis?
Echinocandins
What is the preferred non-biologic agent for treatment of cutaneous lupus if topical treatments fail?
Retinoids
Which antifungal medication requires renal dose adjustment for use in urinary tract infections?
Fluconazole
What is the most common adverse effect associated with Flucytosine?
Myelosuppression
Which antifungal medication has the highest toxicity level among Amphotericin B, Azoles, and Echinocandins?
Amphotericin B
What is the recommended administration requirement for Posaconazole to ensure proper absorption?
Take with food
Which HIV medication is associated with the adverse effect of lactic acidosis?
Zidovudine (AZT)
Which antifungal medication may lead to long-term skin cancer if used extensively?
Voriconazole
Which HIV medication is associated with an increased risk of myocardial infarction (MI)?
Ziagen (abacavir/ABC)
Why is renal dose adjustment required for IV Voriconazole despite it being hepatically eliminated?
'Toxic excipient in IV formulation which is cleared renally'
Which class of antiretroviral drugs can lead to hepatotoxicity and an increased risk of suicidality?
Non-nucleoside reverse transcriptase inhibitors
What is a common side effect associated with the use of Tenofovir disoproxil (TDF)?
Renal dysfunction (Fanconi’s syndrome)
Which antiretroviral drug is known for causing lipodystrophy as a long-term complication?
Reyataz (atazanavir/ATV)
Which antiretroviral combination drug is approved for use in all populations?
Truvada (TDF + emtricitabine)
Which antiretroviral drug is associated with the complication of non-cirrhotic portal hypertension?
Videx EC (didanosine/ddl)
What is a common side effect of Non-nucleoside reverse transcriptase inhibitors like Sustiva (efavirenz/EFV)?
Rash
Which antiretroviral drug combination should be used with caution in patients with existing psychiatric disease due to its effects?
Sustiva (efavirenz/EFV) + Viramune (nevirapine/NVP)
'Biktarvy' is a combination drug that includes which of the following antiretroviral agents?
*Biktarvy (bictegravir + emtricitabine + TAF)
Test your knowledge on oral agents for Rheumatoid Arthritis including Teriflunomide, Dimethyl Fumerate, and Hydroxychloroquine. Learn about preferred initial agents for mild and moderate-severe disease, monitoring requirements, onset of action, and treatment failure criteria.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
