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What is the key pathology associated with rheumatic fever?
What is the key pathology associated with rheumatic fever?
Which of the following is NOT a major criterion in the Jones criteria for rheumatic fever?
Which of the following is NOT a major criterion in the Jones criteria for rheumatic fever?
What is the most common consequence of chronic rheumatic heart disease?
What is the most common consequence of chronic rheumatic heart disease?
Which type of endocarditis is characterized by rapid progression and virulent bacteria?
Which type of endocarditis is characterized by rapid progression and virulent bacteria?
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Which of the following valves is least likely to be involved in rheumatic heart disease?
Which of the following valves is least likely to be involved in rheumatic heart disease?
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What type of fever is associated with rheumatic fever?
What type of fever is associated with rheumatic fever?
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What characteristic finding is indicative of infective endocarditis?
What characteristic finding is indicative of infective endocarditis?
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Which of the following conditions is associated with valvular insufficiency as a complication of rheumatic heart disease?
Which of the following conditions is associated with valvular insufficiency as a complication of rheumatic heart disease?
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What is a characteristic clinical feature of Sydenham chorea?
What is a characteristic clinical feature of Sydenham chorea?
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Which acute condition is a potential complication of infective endocarditis?
Which acute condition is a potential complication of infective endocarditis?
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Which condition is characterized by small masses of fibrin and platelets on heart valves?
Which condition is characterized by small masses of fibrin and platelets on heart valves?
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What type of cardiomyopathy is associated with progressive cardiac dilation and systolic dysfunction?
What type of cardiomyopathy is associated with progressive cardiac dilation and systolic dysfunction?
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Which of the following is a common cause of myocarditis?
Which of the following is a common cause of myocarditis?
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Which condition features subendocardial scars due to ischemic necrosis?
Which condition features subendocardial scars due to ischemic necrosis?
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What is the primary mechanism leading to ischemic heart disease?
What is the primary mechanism leading to ischemic heart disease?
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Which type of myocarditis is most commonly associated with viral infections?
Which type of myocarditis is most commonly associated with viral infections?
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What abnormality is commonly observed in restrictive cardiomyopathy?
What abnormality is commonly observed in restrictive cardiomyopathy?
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What are Osler nodes indicative of?
What are Osler nodes indicative of?
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Which type of cardiomyopathy is characterized by thickened walls without chamber enlargement?
Which type of cardiomyopathy is characterized by thickened walls without chamber enlargement?
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Which condition can cause Libman-Sacks endocarditis?
Which condition can cause Libman-Sacks endocarditis?
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Which congenital heart defect is characterized by a left to right shunt at the atrial level and results in increased pulmonary blood flow?
Which congenital heart defect is characterized by a left to right shunt at the atrial level and results in increased pulmonary blood flow?
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In which type of congenital heart disease does the aorta narrow, commonly seen in males with Turner syndrome?
In which type of congenital heart disease does the aorta narrow, commonly seen in males with Turner syndrome?
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What factor can delay the closure of a patent ductus arteriosus?
What factor can delay the closure of a patent ductus arteriosus?
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Which condition is identified as the most common cyanotic congenital heart disease in children?
Which condition is identified as the most common cyanotic congenital heart disease in children?
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What describes constrictive pericarditis?
What describes constrictive pericarditis?
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What is a common symptom seen in infants with preductal aortic coarctation?
What is a common symptom seen in infants with preductal aortic coarctation?
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Which condition involves the heart being unable to pump blood at a sufficient rate to meet the body's demands?
Which condition involves the heart being unable to pump blood at a sufficient rate to meet the body's demands?
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What is the primary pathological feature of gaseous pericarditis?
What is the primary pathological feature of gaseous pericarditis?
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What complication often accompanies aortic coarctation in over half of affected individuals?
What complication often accompanies aortic coarctation in over half of affected individuals?
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What characterizes the ventricular septal defect (VSD) seen in Tetralogy of Fallot?
What characterizes the ventricular septal defect (VSD) seen in Tetralogy of Fallot?
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What is the most common congenital heart disease in children?
What is the most common congenital heart disease in children?
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Which complication is NOT associated with myocardial infarction?
Which complication is NOT associated with myocardial infarction?
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What characterizes a left to right shunt in congenital heart disease?
What characterizes a left to right shunt in congenital heart disease?
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What is the relationship between aortic valve stenosis and sudden cardiac death?
What is the relationship between aortic valve stenosis and sudden cardiac death?
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What is a common feature of subendocardial infarction?
What is a common feature of subendocardial infarction?
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Which of the following is NOT considered a risk factor for coronary artery disease?
Which of the following is NOT considered a risk factor for coronary artery disease?
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What defines a transmural infarction?
What defines a transmural infarction?
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What is a significant characteristic of cyanotic congenital heart disease?
What is a significant characteristic of cyanotic congenital heart disease?
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Which of the following is a symptom of myocardial infarction?
Which of the following is a symptom of myocardial infarction?
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What is one result of significant left ventricular hypertrophy?
What is one result of significant left ventricular hypertrophy?
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Study Notes
Rheumatic Fever
- Systemic, acute, often recurrent
- Any age, first attack 5-15 years
- Non-suppurative
- Related to prior group A β-hemolytic streptococci
- Streptococcal antigens cross-react with human antigens
- Heart valve glycoproteins, myocardial smooth muscle, sarcolemma, tissue glycoproteins in joints
- Jones criteria: 2 major or 1 major, 2 minor needed
- Major Criteria*:
- Migratory polyarthritis in large joints
- Carditis
- Subcutaneous nodules
- Sydenham chorea
- Erythema marginatum
- Minor Criteria*:
- Prior strep infection
- Fever
- Elevated strep antigens
- Arthralgia
- Elevated acute phase reactants
Key Pathology
- Aschoff bodies, Anitschkow cells
Macroscopic Findings
- Diffuse inflammation, pancarditis
- Fibrinous/serofibrinous pericarditis
Chronic Rheumatic Heart Disease
- Deforming fibrotic valvular disease
- Mitral valve stenosis
- Permanent dysfunction
- Leaflet thickening
- Commissural fusion
- Shortening, thickening, and fusion of chordae tendineae
- Fish mouth/buttonhole stenosis
- MacCallum plaques
- Verrucae
Chronic Rheumatic Heart Disease
- Deforming fibrotic valvular disease
- Mitral valve stenosis
- Permanent dysfunction
- Leaflet thickening
- Commissural fusion
- Shortening, thickening, and fusion of chordae tendineae
- Fish mouth/buttonhole stenosis
- MacCallum plaques
- Verrucae
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Description
This quiz explores the key concepts of Rheumatic Fever, including its clinical criteria, pathology, and chronic effects on the heart. Learn about the major and minor criteria established by the Jones criteria and the macroscopic findings associated with the disease. Ideal for medical students and professionals looking to test their knowledge on this condition.