Rheumatic Fever Overview
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Questions and Answers

What is the key pathology associated with rheumatic fever?

  • Myocardial hypertrophy
  • Aschoff bodies and Anitschkow cells (correct)
  • Atherosclerotic plaques
  • Calcific degeneration of valves
  • Which of the following is NOT a major criterion in the Jones criteria for rheumatic fever?

  • Migratory polyarthritis
  • Erythema marginatum
  • Subcutaneous nodules
  • Fever (correct)
  • What is the most common consequence of chronic rheumatic heart disease?

  • Aortic regurgitation
  • Mitral valve stenosis (correct)
  • Pulmonary valve stenosis
  • Right-sided heart failure
  • Which type of endocarditis is characterized by rapid progression and virulent bacteria?

    <p>Acute bacterial endocarditis</p> Signup and view all the answers

    Which of the following valves is least likely to be involved in rheumatic heart disease?

    <p>Pulmonary valve</p> Signup and view all the answers

    What type of fever is associated with rheumatic fever?

    <p>Intermittent fever</p> Signup and view all the answers

    What characteristic finding is indicative of infective endocarditis?

    <p>Bulky friable vegetations</p> Signup and view all the answers

    Which of the following conditions is associated with valvular insufficiency as a complication of rheumatic heart disease?

    <p>Chronic aortic regurgitation</p> Signup and view all the answers

    What is a characteristic clinical feature of Sydenham chorea?

    <p>Involuntary movements</p> Signup and view all the answers

    Which acute condition is a potential complication of infective endocarditis?

    <p>Acute renal failure</p> Signup and view all the answers

    Which condition is characterized by small masses of fibrin and platelets on heart valves?

    <p>Non-bacterial thrombotic endocarditis</p> Signup and view all the answers

    What type of cardiomyopathy is associated with progressive cardiac dilation and systolic dysfunction?

    <p>Dilated cardiomyopathy</p> Signup and view all the answers

    Which of the following is a common cause of myocarditis?

    <p>Viral infections</p> Signup and view all the answers

    Which condition features subendocardial scars due to ischemic necrosis?

    <p>Dilated cardiomyopathy</p> Signup and view all the answers

    What is the primary mechanism leading to ischemic heart disease?

    <p>Imbalance between oxygen demand and supply</p> Signup and view all the answers

    Which type of myocarditis is most commonly associated with viral infections?

    <p>Idiopathic giant cell myocarditis</p> Signup and view all the answers

    What abnormality is commonly observed in restrictive cardiomyopathy?

    <p>Decreased ventricular compliance</p> Signup and view all the answers

    What are Osler nodes indicative of?

    <p>Bacterial endocarditis</p> Signup and view all the answers

    Which type of cardiomyopathy is characterized by thickened walls without chamber enlargement?

    <p>Hypertrophic cardiomyopathy</p> Signup and view all the answers

    Which condition can cause Libman-Sacks endocarditis?

    <p>Systemic lupus erythematosus (SLE)</p> Signup and view all the answers

    Which congenital heart defect is characterized by a left to right shunt at the atrial level and results in increased pulmonary blood flow?

    <p>Patent ductus arteriosus</p> Signup and view all the answers

    In which type of congenital heart disease does the aorta narrow, commonly seen in males with Turner syndrome?

    <p>Aortic coarctation</p> Signup and view all the answers

    What factor can delay the closure of a patent ductus arteriosus?

    <p>Hypoxia</p> Signup and view all the answers

    Which condition is identified as the most common cyanotic congenital heart disease in children?

    <p>Tetralogy of Fallot</p> Signup and view all the answers

    What describes constrictive pericarditis?

    <p>Heart surrounded by fibrous scar tissue</p> Signup and view all the answers

    What is a common symptom seen in infants with preductal aortic coarctation?

    <p>Cyanosis of the lower body</p> Signup and view all the answers

    Which condition involves the heart being unable to pump blood at a sufficient rate to meet the body's demands?

    <p>Congestive heart failure</p> Signup and view all the answers

    What is the primary pathological feature of gaseous pericarditis?

    <p>Tuberculous infection in the pericardial sac</p> Signup and view all the answers

    What complication often accompanies aortic coarctation in over half of affected individuals?

    <p>Bicuspid aortic valve</p> Signup and view all the answers

    What characterizes the ventricular septal defect (VSD) seen in Tetralogy of Fallot?

    <p>VSD with aortic override</p> Signup and view all the answers

    What is the most common congenital heart disease in children?

    <p>Ventricular Septal Defect</p> Signup and view all the answers

    Which complication is NOT associated with myocardial infarction?

    <p>Constipation</p> Signup and view all the answers

    What characterizes a left to right shunt in congenital heart disease?

    <p>Volume overload in the right heart</p> Signup and view all the answers

    What is the relationship between aortic valve stenosis and sudden cardiac death?

    <p>Contributes to arrhythmias and heart failure</p> Signup and view all the answers

    What is a common feature of subendocardial infarction?

    <p>Least well pursued area</p> Signup and view all the answers

    Which of the following is NOT considered a risk factor for coronary artery disease?

    <p>Regular exercise</p> Signup and view all the answers

    What defines a transmural infarction?

    <p>Results in full-thickness damage to the myocardial wall</p> Signup and view all the answers

    What is a significant characteristic of cyanotic congenital heart disease?

    <p>Causes secondary polycythemia</p> Signup and view all the answers

    Which of the following is a symptom of myocardial infarction?

    <p>Nausea and vomiting</p> Signup and view all the answers

    What is one result of significant left ventricular hypertrophy?

    <p>Increased risk of sudden cardiac death</p> Signup and view all the answers

    Study Notes

    Rheumatic Fever

    • Systemic, acute, often recurrent
    • Any age, first attack 5-15 years
    • Non-suppurative
    • Related to prior group A β-hemolytic streptococci
    • Streptococcal antigens cross-react with human antigens
    • Heart valve glycoproteins, myocardial smooth muscle, sarcolemma, tissue glycoproteins in joints
    • Jones criteria: 2 major or 1 major, 2 minor needed
    • Major Criteria*:
    • Migratory polyarthritis in large joints
    • Carditis
    • Subcutaneous nodules
    • Sydenham chorea
    • Erythema marginatum
    • Minor Criteria*:
    • Prior strep infection
    • Fever
    • Elevated strep antigens
    • Arthralgia
    • Elevated acute phase reactants

    Key Pathology

    • Aschoff bodies, Anitschkow cells

    Macroscopic Findings

    • Diffuse inflammation, pancarditis
    • Fibrinous/serofibrinous pericarditis

    Chronic Rheumatic Heart Disease

    • Deforming fibrotic valvular disease
    • Mitral valve stenosis
    • Permanent dysfunction
    • Leaflet thickening
    • Commissural fusion
    • Shortening, thickening, and fusion of chordae tendineae
    • Fish mouth/buttonhole stenosis
    • MacCallum plaques
    • Verrucae

    Chronic Rheumatic Heart Disease

    • Deforming fibrotic valvular disease
    • Mitral valve stenosis
    • Permanent dysfunction
    • Leaflet thickening
    • Commissural fusion
    • Shortening, thickening, and fusion of chordae tendineae
    • Fish mouth/buttonhole stenosis
    • MacCallum plaques
    • Verrucae

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    Description

    This quiz explores the key concepts of Rheumatic Fever, including its clinical criteria, pathology, and chronic effects on the heart. Learn about the major and minor criteria established by the Jones criteria and the macroscopic findings associated with the disease. Ideal for medical students and professionals looking to test their knowledge on this condition.

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