Podcast
Questions and Answers
What is the main challenge in conducting research in reproductive immunology?
What is the main challenge in conducting research in reproductive immunology?
- Limited understanding of NK cell analysis
- Difficulty in recruiting controls for studies
- Lack of funding for large trials
- Poor study design and over-interpretation of results (correct)
What is a common issue in defining the 'patient' group in NK cell analysis studies?
What is a common issue in defining the 'patient' group in NK cell analysis studies?
- Lack of clear definitions of RIF and RPL
- Inadequate control groups
- Heterogeneity of the group (correct)
- Insufficient sample size
Why is NK cell analysis in reproductive medicine considered both a 'marketing dream' and an 'academic nightmare'?
Why is NK cell analysis in reproductive medicine considered both a 'marketing dream' and an 'academic nightmare'?
- Because it is a new and untested area of research
- Because it is only used in IVF treatment
- Because it is a complex and poorly understood area of research
- Because it has high commercial potential but lacks scientific rigor (correct)
What is a major limitation in NK cell analysis studies?
What is a major limitation in NK cell analysis studies?
What should clinicians consider when interpreting NK cell analysis results?
What should clinicians consider when interpreting NK cell analysis results?
Why are controls difficult to recruit and define in NK cell analysis studies?
Why are controls difficult to recruit and define in NK cell analysis studies?
What is a major challenge in immunological testing related to natural killer cells?
What is a major challenge in immunological testing related to natural killer cells?
What is the primary method used to assess uNK cells?
What is the primary method used to assess uNK cells?
What is a limitation of counting CD56+ cells in uNK cell analysis?
What is a limitation of counting CD56+ cells in uNK cell analysis?
Why is it challenging to develop a reliable method of counting uNK cells in endometrium?
Why is it challenging to develop a reliable method of counting uNK cells in endometrium?
Why is it important to consider the day of the cycle when interpreting uNK cell levels?
Why is it important to consider the day of the cycle when interpreting uNK cell levels?
What is a criticism of using pNK cells as a surrogate for uNK cells?
What is a criticism of using pNK cells as a surrogate for uNK cells?
What is the main advantage of Immunohistochemistry (IHC) over traditional tissue staining techniques?
What is the main advantage of Immunohistochemistry (IHC) over traditional tissue staining techniques?
What is a major limitation of using flow cytometry to isolate uNK cells?
What is a major limitation of using flow cytometry to isolate uNK cells?
What is a characteristic feature of RPL endometrium?
What is a characteristic feature of RPL endometrium?
Why is IHC preferred over flow cytometry for studying uNK cells?
Why is IHC preferred over flow cytometry for studying uNK cells?
What is a disadvantage of using flow cytometry for immunophenotyping?
What is a disadvantage of using flow cytometry for immunophenotyping?
What is a limitation of using large endometrial specimens for flow cytometry?
What is a limitation of using large endometrial specimens for flow cytometry?
What percentage of uNK and pNK cells are of different phenotype?
What percentage of uNK and pNK cells are of different phenotype?
What is a limitation of endometrial biopsy?
What is a limitation of endometrial biopsy?
What may pNK cell activity represent?
What may pNK cell activity represent?
What can affect the results of pNK cell analysis?
What can affect the results of pNK cell analysis?
What is the corrected range for pNK cells in females?
What is the corrected range for pNK cells in females?
What is one of the methods used for the analysis of pNK cells?
What is one of the methods used for the analysis of pNK cells?
