Renal Physiology: Filtration Rate and Flow

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Questions and Answers

What effect does afferent arteriole constriction have on the glomeruli filtration rate?

  • No effect
  • Increased
  • Decreased (correct)
  • Variable

How does increased plasma protein concentration affect filtration fraction?

  • Decreased (correct)
  • Increased
  • Remains constant
  • No effect

What is the impact of dehydration on renal plasma flow?

  • Varies with hydration status
  • Increased
  • No effect
  • Decreased (correct)

What happens to the filtration fraction when the efferent arteriole is constricted by Angiotensin 2?

<p>Increased (A)</p> Signup and view all the answers

What effect does constriction of the ureter have on the glomeruli filtration rate?

<p>Decreased (B)</p> Signup and view all the answers

What is the effect of decreased plasma protein concentration on the filtration fraction?

<p>It increases the filtration fraction. (A)</p> Signup and view all the answers

How does the constriction of the ureter impact glomeruli filtration rate?

<p>It decreases the glomeruli filtration rate. (A)</p> Signup and view all the answers

What is the impact of Angiotensin 2 on renal plasma flow?

<p>It increases renal plasma flow. (C)</p> Signup and view all the answers

Which factor causes an increase in the filtration fraction?

<p>Dehydration. (D)</p> Signup and view all the answers

What happens to the glomeruli filtration rate when prostaglandins cause afferent arteriole dilation?

<p>It increases. (A)</p> Signup and view all the answers

Which of the following scenarios would result in a decreased glomeruli filtration rate and renal plasma flow?

<p>Afferent arteriole constriction (C)</p> Signup and view all the answers

A patient experiences severe dehydration. Which of the following accurately describes the expected changes in their kidney function?

<p>Decreased glomeruli filtration rate and decreased renal plasma flow. (D)</p> Signup and view all the answers

If a patient has a filtration fraction that is lower than normal, which of the following could be a contributing factor?

<p>Increased plasma protein concentration (A)</p> Signup and view all the answers

What is the likely effect of Angiotensin 2 on the filtration fraction and renal plasma flow?

<p>Increased filtration fraction and increased renal plasma flow (C)</p> Signup and view all the answers

Which of the following will result in a decrease in both glomeruli filtration rate and filtration fraction?

<p>Constriction of the ureter (D)</p> Signup and view all the answers

Which scenario would lead to simultaneous increase in both glomeruli filtration rate (GFR) and filtration fraction?

<p>Efferent arteriole constriction (Angiotensin 2) (A)</p> Signup and view all the answers

Which of the following conditions would result in a decreased glomeruli filtration rate (GFR) but an increased filtration fraction?

<p>Dehydration (C)</p> Signup and view all the answers

If a patient has a decreased renal plasma flow and a decreased glomeruli filtration rate (GFR), which of the following could be the cause?

<p>Afferent arteriole constriction (A)</p> Signup and view all the answers

Which of these conditions would result in an increase in the filtration fraction, while not affecting, or increasing, the glomeruli filtration rate?

<p>Decreased plasma protein concentration (B)</p> Signup and view all the answers

A patient has a decrease in both their glomeruli filtration rate (GFR) and their filtration fraction. Which scenario best explains this observation?

<p>Increased plasma protein concentration (C)</p> Signup and view all the answers

A patient presents with an increased filtration fraction and decreased renal plasma flow. Based on the provided table, which factor is most likely contributing to these changes?

<p>Efferent arteriole constriction (Angiotensin 2) (B)</p> Signup and view all the answers

If a patient exhibits a decreased glomeruli filtration rate and a decreased filtration fraction, which of the following scenarios is the most likely cause, based on the provided table?

<p>Constriction of the ureter. (A)</p> Signup and view all the answers

Which of the following scenarios is most likely to result in an increase in both the glomeruli filtration rate and the filtration fraction?

<p>Decreased plasma protein concentration (D)</p> Signup and view all the answers

A patient has a known condition causing increased levels of Angiotensin 2. What is the most likely combined effect on their glomeruli filtration rate (GFR) and renal plasma flow, according to the table?

<p>Decreased GFR, increased renal plasma flow (C)</p> Signup and view all the answers

Which option describes a scenario where renal plasma flow is reduced, while the filtration fraction is either unchanged or increased, based solely on the table provided?

<p>Afferent arteriole constriction (C)</p> Signup and view all the answers

Which of the following scenarios would result in a decrease in glomeruli filtration rate and an increase in filtration fraction?

<p>Dehydration. (B)</p> Signup and view all the answers

A patient presents with decreased glomeruli filtration rate and decreased renal plasma flow. Based on the table, which of the following could be the cause?

<p>Afferent arteriole constriction. (A)</p> Signup and view all the answers

Which of the following conditions would lead to an increase in filtration fraction without any corresponding change or increase in glomeruli filtration rate?

<p>Efferent arteriole constriction due to Angiotensin 2. (C)</p> Signup and view all the answers

A patient has a decreased filtration fraction and a decreased glomeruli filtration rate. Which scenario best explains this observation?

<p>Increased plasma protein concentration. (B)</p> Signup and view all the answers

Which of the following conditions would result in an increased renal plasma flow in conjunction with a decreased glomeruli filtration rate?

<p>Increased levels of Angiotensin 2. (A)</p> Signup and view all the answers

Flashcards

Afferent arteriole constriction

Constricting the afferent arteriole reduces blood flow into the glomerulus, leading to a decrease in both glomerular filtration rate and renal plasma flow.

Efferent arteriole constriction (Angiotensin 2)

Angiotensin 2 constricts the efferent arteriole, increasing pressure inside the glomerulus. This raises glomerular filtration rate while renal plasma flow might remain the same, leading to a higher filtration fraction.

Increased plasma protein concentration

Increased plasma protein concentration makes the blood thicker, hindering the filtration process. This results in a lower glomerular filtration rate and a lower filtration fraction.

Constriction of ureter

Constricting the ureter, the tube that transports urine, can reduce pressure within the kidney, leading to a decrease in glomerular filtration rate and filtration fraction.

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Dehydration

Dehydration increases blood viscosity, reduces blood flow to the kidneys, and leads to an increase in the concentration of solutes in the blood. This combination results in a lower GFR, a lower RPF, and a higher filtration fraction.

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Afferent arteriole constriction: How does it impact GFR and RPF?

Constricting the afferent arteriole decreases blood flow into the glomerulus, leading to reduced glomerular filtration rate (GFR) and renal plasma flow (RPF).

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Angiotensin 2 & Efferent Arteriole: Impact on GFR and Filtration Fraction?

Angiotensin 2 constricts the efferent arteriole, increasing pressure within the glomerulus, raising GFR. While RPF remains the same, the increased pressure leads to a higher filtration fraction.

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Plasma Protein Concentration: How does it affect GFR and Filtration Fraction?

Increased protein concentration makes the blood thicker, hindering filtration, resulting in a lower GFR and a lower filtration fraction.

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Ureter Constriction: Impact on Filtration?

Constriction of the ureter, the tube carrying urine, reduces pressure within the kidney, leading to a decrease in GFR and filtration fraction.

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Dehydration and Kidney Function: Explain changes in GFR, RPF, and Filtration Fraction.

Dehydration increases blood viscosity, reduces blood flow to the kidneys, leading to a lower GFR and RPF, but increased filtration fraction.

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What happens to GFR and RPF when the afferent arteriole constricts?

Constricting the afferent arteriole reduces blood flow into the glomerulus, leading to a decrease in both glomerular filtration rate (GFR) and renal plasma flow (RPF).

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How does Angiotensin II affect GFR and filtration fraction?

Angiotensin II constricting the efferent arteriole increases pressure within the glomerulus. This leads to a higher GFR while RPF remains the same, resulting in a higher filtration fraction.

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How does increased plasma protein concentration affect GFR and filtration fraction?

Increased plasma protein concentration makes blood thicker, hindering filtration, resulting in a lower GFR and filtration fraction.

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What happens to GFR and filtration fraction when the ureter constricts?

Constricting the ureter reduces pressure within the kidney, leading to a decrease in GFR and filtration fraction.

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How does dehydration affect GFR, RPF, and filtration fraction?

Dehydration increases blood viscosity, reduces blood flow to the kidneys, leading to a lower GFR and RPF, but an increased filtration fraction.

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Afferent Arteriole Constriction: Impact on GFR and RPF?

Constricting the afferent arteriole reduces blood flow into the glomerulus, causing a decrease in both glomerular filtration rate (GFR) and renal plasma flow (RPF).

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Efferent Arteriole Constriction (Angiotensin 2): Impact on GFR & Filtration Fraction?

Angiotensin 2 constricts the efferent arteriole, increasing pressure inside the glomerulus. This raises GFR, while RPF might remain the same, leading to a higher filtration fraction.

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Increased Plasma Protein Concentration: Impact on GFR & Filtration Fraction?

Increased plasma protein concentration thickens the blood, making it harder for fluid to move through the glomerulus, decreasing GFR and the filtration fraction.

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Ureter Constriction: Impact on GFR & Filtration Fraction?

Constricting the ureter, which carries urine, reduces pressure within the kidney, leading to a decrease in glomerular filtration rate (GFR) and filtration fraction.

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Dehydration: Impact on GFR, RPF, and Filtration Fraction?

Dehydration increases blood viscosity (thickness), reduces blood flow to the kidneys, and raises solute concentration in blood. This leads to a lower GFR, a lower RPF, but a higher filtration fraction.

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Afferent arteriole constriction: GFR & RPF?

Constricting the afferent arteriole reduces blood flow into the glomerulus, lowering both glomerular filtration rate (GFR) and renal plasma flow (RPF).

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Efferent arteriole constriction (Angiotensin II): GFR & Filtration Fraction?

Constricting the efferent arteriole increases pressure inside the glomerulus, raising GFR. Although RPF might stay the same, the increased pressure leads to a higher filtration fraction.

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Increased plasma protein: GFR & Filtration Fraction?

Increased protein in the blood makes it thicker, slowing down filtration. This results in a lower GFR and a lower filtration fraction.

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Ureter constriction: GFR & Filtration Fraction?

Constricting the ureter, the tube carrying urine, reduces pressure within the kidney, decreasing GFR and filtration fraction.

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Dehydration: GFR, RPF, & Filtration Fraction?

Dehydration makes the blood thicker, reduces blood flow to the kidneys, and increases the concentration of solutes in the blood. This leads to a lower GFR, a lower RPF, but a higher filtration fraction.

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Study Notes

Glomeruli Filtration Rate, Renal Plasma Flow, and Filtration Fraction

  • Afferent arteriole constriction: Decreases Glomeruli Filtration Rate and Renal Plasma Flow. Filtration Fraction is unclear.

  • Efferent arteriole constriction (Angiotensin 2): Increases Glomeruli Filtration Rate, Renal Plasma Flow increases, and Filtration Fraction increases.

  • Increased plasma protein concentration: Decreases Glomeruli Filtration Rate and Renal Plasma Flow. Filtration Fraction is unclear.

  • Decreased plasma protein concentration: Increases Glomeruli Filtration Rate and Renal Plasma Flow. Filtration Fraction increases.

  • Constriction of ureter: Decreases Glomeruli Filtration Rate and Renal Plasma Flow. Filtration Fraction is unclear.

  • Dehydration: Decreases Glomeruli Filtration Rate and Renal Plasma Flow. Filtration Fraction is unclear.

  • Prostaglandins (Afferent arteriole dilation): Increases Glomeruli Filtration Rate, and Renal Plasma Flow. Filtration Fraction is unclear.

  • Angiotensin 2: Decreases Glomeruli Filtration Rate, Renal plasma flow decreases, and Filtration fraction increases.

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