Rabies Virus and Its Impact Quiz

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How does the rabies virus primarily gain access to the nervous system?

Via inhalation

Through exposed peripheral nerve synapses in bite wounds (correct)

Through the bloodstream

By crossing the blood-brain barrier

Which family does the infectious agent of rabies belong to?

Filoviridae

Rhabdoviridae (correct)

Flaviviridae

Coronaviridae

What is the most common Lyssavirus infection in humans?

Dogs

Cats

Rabies virus (correct)

Bats

What is the primary mode of rabies virus transmission?

Direct contact with infected animals Signup and view all the answers

What specimens are required for definitive antemortem diagnosis of rabies?

Cerebrospinal fluid, saliva, serum, and skin biopsies from the nape of the neck Signup and view all the answers

Why is rabies diagnosis often missed at the first clinical encounter in the United States?

The exposure history is often inaccurate or difficult to elicit Signup and view all the answers

What can incorrectly suggest a diagnosis of rabies in the absence of an accurate history of prior IVIG administration?

Finding RLNAs in serum Signup and view all the answers

Which organization is designated as the national rabies reference laboratory for the United States?

Centers for Disease Control and Prevention (CDC) Signup and view all the answers

What specimens can confirm the diagnosis of rabies in unvaccinated encephalitic patients?

Cerebrospinal fluid samples Signup and view all the answers

Why is sequential sample collection indicated if initial testing for rabies is negative but clinical suspicion remains high?

To increase the likelihood of detecting virus and antibodies as the illness progresses Signup and view all the answers

What is the main reservoir of rabies virus in many low- and middle-income countries?

Dogs Signup and view all the answers

Which viral lineage is classified into canine and New World bat?

Rabies virus Signup and view all the answers

What is the approximate range of rabies exposures in travelers per 100,000 travelers?

160–200 Signup and view all the answers

What characteristic symptom is associated with the neurologic phase of rabies?

Hydrophobia Signup and view all the answers

In which phase of the disease does swallowing muscle spasm stimulated by water typically occur?

Neurologic phase Signup and view all the answers

Which body part is often affected first in paralytic rabies?

Bitten extremity Signup and view all the answers

Where have non–rabies lyssaviruses caused human deaths?

Australia Signup and view all the answers

How is the rabies virus classified based on genetic differentiations and on the reservoir species in which they circulate?

Two major genetic lineages: canine and New World bat Signup and view all the answers

Rabies Virus and Its Impact Quiz

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Questions and Answers

How does the rabies virus primarily gain access to the nervous system?

Which family does the infectious agent of rabies belong to?

What is the most common Lyssavirus infection in humans?

What is the primary mode of rabies virus transmission?

What specimens are required for definitive antemortem diagnosis of rabies?

Why is rabies diagnosis often missed at the first clinical encounter in the United States?

What can incorrectly suggest a diagnosis of rabies in the absence of an accurate history of prior IVIG administration?

Which organization is designated as the national rabies reference laboratory for the United States?

What specimens can confirm the diagnosis of rabies in unvaccinated encephalitic patients?

Why is sequential sample collection indicated if initial testing for rabies is negative but clinical suspicion remains high?

What is the main reservoir of rabies virus in many low- and middle-income countries?

Which viral lineage is classified into canine and New World bat?

What is the approximate range of rabies exposures in travelers per 100,000 travelers?

What characteristic symptom is associated with the neurologic phase of rabies?

In which phase of the disease does swallowing muscle spasm stimulated by water typically occur?

Which body part is often affected first in paralytic rabies?

Where have non–rabies lyssaviruses caused human deaths?

How is the rabies virus classified based on genetic differentiations and on the reservoir species in which they circulate?

What tissues can increase the risk for successful infection?

In what phase does pain and paresthesia at the site of exposure often occur?

Where has canine rabies been found to remain enzootic?

Which mammals are believed to be susceptible to rabies virus infection?

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