Rabies Virus and Its Impact Quiz
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Questions and Answers

How does the rabies virus primarily gain access to the nervous system?

  • Via inhalation
  • Through exposed peripheral nerve synapses in bite wounds (correct)
  • Through the bloodstream
  • By crossing the blood-brain barrier
  • Which family does the infectious agent of rabies belong to?

  • Filoviridae
  • Rhabdoviridae (correct)
  • Flaviviridae
  • Coronaviridae
  • What is the most common Lyssavirus infection in humans?

  • Dogs
  • Cats
  • Rabies virus (correct)
  • Bats
  • What is the primary mode of rabies virus transmission?

    <p>Direct contact with infected animals (C)</p> Signup and view all the answers

    What specimens are required for definitive antemortem diagnosis of rabies?

    <p>Cerebrospinal fluid, saliva, serum, and skin biopsies from the nape of the neck (A)</p> Signup and view all the answers

    Why is rabies diagnosis often missed at the first clinical encounter in the United States?

    <p>The exposure history is often inaccurate or difficult to elicit (B)</p> Signup and view all the answers

    What can incorrectly suggest a diagnosis of rabies in the absence of an accurate history of prior IVIG administration?

    <p>Finding RLNAs in serum (D)</p> Signup and view all the answers

    Which organization is designated as the national rabies reference laboratory for the United States?

    <p>Centers for Disease Control and Prevention (CDC) (A)</p> Signup and view all the answers

    What specimens can confirm the diagnosis of rabies in unvaccinated encephalitic patients?

    <p>Cerebrospinal fluid samples (A)</p> Signup and view all the answers

    Why is sequential sample collection indicated if initial testing for rabies is negative but clinical suspicion remains high?

    <p>To increase the likelihood of detecting virus and antibodies as the illness progresses (B)</p> Signup and view all the answers

    What is the main reservoir of rabies virus in many low- and middle-income countries?

    <p>Dogs (B)</p> Signup and view all the answers

    Which viral lineage is classified into canine and New World bat?

    <p>Rabies virus (D)</p> Signup and view all the answers

    What is the approximate range of rabies exposures in travelers per 100,000 travelers?

    <p>160–200 (D)</p> Signup and view all the answers

    What characteristic symptom is associated with the neurologic phase of rabies?

    <p>Hydrophobia (D)</p> Signup and view all the answers

    In which phase of the disease does swallowing muscle spasm stimulated by water typically occur?

    <p>Neurologic phase (B)</p> Signup and view all the answers

    Which body part is often affected first in paralytic rabies?

    <p>Bitten extremity (C)</p> Signup and view all the answers

    Where have non–rabies lyssaviruses caused human deaths?

    <p>Australia (D)</p> Signup and view all the answers

    How is the rabies virus classified based on genetic differentiations and on the reservoir species in which they circulate?

    <p>Two major genetic lineages: canine and New World bat (A)</p> Signup and view all the answers

    What tissues can increase the risk for successful infection?

    <p>Highly innervated tissues (D)</p> Signup and view all the answers

    In what phase does pain and paresthesia at the site of exposure often occur?

    <p>Prodromal phase (A)</p> Signup and view all the answers

    Where has canine rabies been found to remain enzootic?

    <p>Africa (D)</p> Signup and view all the answers

    Which mammals are believed to be susceptible to rabies virus infection?

    <p>All mammals (D)</p> Signup and view all the answers

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