Rabies Virus and Its Impact Quiz
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Questions and Answers

How does the rabies virus primarily gain access to the nervous system?

  • Via inhalation
  • Through exposed peripheral nerve synapses in bite wounds (correct)
  • Through the bloodstream
  • By crossing the blood-brain barrier

Which family does the infectious agent of rabies belong to?

  • Filoviridae
  • Rhabdoviridae (correct)
  • Flaviviridae
  • Coronaviridae

What is the most common Lyssavirus infection in humans?

  • Dogs
  • Cats
  • Rabies virus (correct)
  • Bats

What is the primary mode of rabies virus transmission?

<p>Direct contact with infected animals (C)</p> Signup and view all the answers

What specimens are required for definitive antemortem diagnosis of rabies?

<p>Cerebrospinal fluid, saliva, serum, and skin biopsies from the nape of the neck (A)</p> Signup and view all the answers

Why is rabies diagnosis often missed at the first clinical encounter in the United States?

<p>The exposure history is often inaccurate or difficult to elicit (B)</p> Signup and view all the answers

What can incorrectly suggest a diagnosis of rabies in the absence of an accurate history of prior IVIG administration?

<p>Finding RLNAs in serum (D)</p> Signup and view all the answers

Which organization is designated as the national rabies reference laboratory for the United States?

<p>Centers for Disease Control and Prevention (CDC) (A)</p> Signup and view all the answers

What specimens can confirm the diagnosis of rabies in unvaccinated encephalitic patients?

<p>Cerebrospinal fluid samples (A)</p> Signup and view all the answers

Why is sequential sample collection indicated if initial testing for rabies is negative but clinical suspicion remains high?

<p>To increase the likelihood of detecting virus and antibodies as the illness progresses (B)</p> Signup and view all the answers

What is the main reservoir of rabies virus in many low- and middle-income countries?

<p>Dogs (B)</p> Signup and view all the answers

Which viral lineage is classified into canine and New World bat?

<p>Rabies virus (D)</p> Signup and view all the answers

What is the approximate range of rabies exposures in travelers per 100,000 travelers?

<p>160–200 (D)</p> Signup and view all the answers

What characteristic symptom is associated with the neurologic phase of rabies?

<p>Hydrophobia (D)</p> Signup and view all the answers

In which phase of the disease does swallowing muscle spasm stimulated by water typically occur?

<p>Neurologic phase (B)</p> Signup and view all the answers

Which body part is often affected first in paralytic rabies?

<p>Bitten extremity (C)</p> Signup and view all the answers

Where have non–rabies lyssaviruses caused human deaths?

<p>Australia (D)</p> Signup and view all the answers

How is the rabies virus classified based on genetic differentiations and on the reservoir species in which they circulate?

<p>Two major genetic lineages: canine and New World bat (A)</p> Signup and view all the answers

What tissues can increase the risk for successful infection?

<p>Highly innervated tissues (D)</p> Signup and view all the answers

In what phase does pain and paresthesia at the site of exposure often occur?

<p>Prodromal phase (A)</p> Signup and view all the answers

Where has canine rabies been found to remain enzootic?

<p>Africa (D)</p> Signup and view all the answers

Which mammals are believed to be susceptible to rabies virus infection?

<p>All mammals (D)</p> Signup and view all the answers

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