T1 L20: Pharmacological aspects of immunology 2: biological therapies (AMG)

Which of the following biologics is a monoclonal antibody against B cells?

Which of the following biologics is a T cell co-stimulation inhibitor?

Which of the following biologics is an IL-1R antagonist?

Which of the following biologics is a fully human anti-TNF-a monoclonal antibody?

Which of the following biologics is a PEGylated anti-TNF-a monoclonal antibody fragment?

Which of the following biologics is administered as an intravenous infusion?

Which of the following biologics is administered by subcutaneous injection twice a week or weekly?

Which of the following is a synthetic DMARD used in the treatment of rheumatoid arthritis?

Which of the following adverse effects is associated with methotrexate?

Which of the following JAK inhibitors selectively inhibits JAK1 and JAK3?

Which of the following adverse effects is associated with tofacitinib?

Which of the following biologic agents is recommended if a patient has failed to respond to treatment with at least two standard DMARDs?

Which of the following is a common adverse effect of anti-TNF drugs?

Which of the following is a requirement for initiating biological therapy in rheumatoid arthritis?

Which biologic agent is a monoclonal antibody against B cells?

Which biologic agent is a T-cell co-stimulation inhibitor?

Which biologic agents target IL-6R?

Which biologic agent is an IL-1R antagonist?

Which mechanism is responsible for the depletion of B cells by rituximab?

Which biologic agent is a competitive inhibitor of CD28?

Which biologic agent is used in the treatment of systemic juvenile idiopathic arthritis?

Which biologic agent is administered as a subcutaneous injection?

Which adverse effect is associated with biological therapies?

Which type of drugs slow the clinical and radiographic progression of rheumatoid arthritis?

Which drug is considered the first choice DMARD for rheumatoid arthritis?

What is the function of Methotrexate (MTX) in the treatment of rheumatoid arthritis?

What is the recommended dosage range for Methotrexate (MTX) in the treatment of rheumatoid arthritis?

What is the role of Methotrexate (MTX) in combination therapies for rheumatoid arthritis?

What can be taken as a supplement to reduce the side-effects caused by folic acid depletion when taking Methotrexate (MTX)?

What is the email address of Dr. Annamaria Gal?

Which of the following is a potential side effect of anti-inflammatory immunosuppressive drugs?

Which molecule is a central player in the pathogenesis of rheumatoid arthritis?

Which drug is considered an anchor drug in the treatment of rheumatoid arthritis?

Which biologic agent is a selective inhibitor of JAK1 and JAK3?

Which of the following is the main cause of rheumatoid arthritis?

What is the role of anti-inflammatory drugs in the treatment of rheumatoid arthritis?

Which type of drugs are used to slow down the progression of rheumatoid arthritis?

What is the recommended dosage range for Methotrexate (MTX) in the treatment of rheumatoid arthritis?

Which part of the chimeric antibody is mouse-derived?

Which part of the chimeric antibody is human-derived?

What is the mechanism by which the chimeric antibody eliminates TNF from the body?

Which biologic therapy is recommended by the National Institute for Clinical Excellence (NICE) only when combined with Ms. Fixate Etanercept?

Which pro-inflammatory cytokine is targeted by anti-TNF therapy in the treatment of rheumatoid arthritis?

What is the trade name of the anti-TNF antibody adalimumab?

Which drug has recently surpassed anti-TNF medications in terms of drug sales?

Which pro-inflammatory cytokine has an important role in the mechanism of rheumatoid arthritis and is a potential target for therapy?

Which of the following is a biologic drug used in the treatment of rheumatoid arthritis?

What is the normal range for erythrocyte sedimentation rate (ESR) in men?

Which of the following biologics is a monoclonal antibody against B cells?

Which biologic agent is a T-cell co-stimulation inhibitor?

Which of the following drugs is a non-steroidal anti-inflammatory drug (NSAID)?

What is the mechanism of action of non-steroidal anti-inflammatory drugs (NSAIDs)?

Which drug is considered the gold standard for treating rheumatoid arthritis?

Which category of drugs brought a dramatic increase in the quality of life for people with rheumatoid arthritis?

Which of the following vaccines can be administered to patients without posing a risk for increased risk of infections?

What is the approach for administering anthrax vaccine to patients?

What percentage of patients report that their symptoms are not improved with anti-TNF therapy?

What is the main reason for patients not experiencing a biological effect from TNF antibodies?

What are the other options that can be considered if patients can't tolerate anti-TNF therapy?

What is the role of other biologics in the treatment of patients who don't respond to anti-TNF therapy?