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Questions and Answers
What is the measure of a substituent's hydrophobicity relative to hydrogen?
What is the measure of a substituent's hydrophobicity relative to hydrogen?
- log P
- P
- QSAR
- π (correct)
What is the purpose of QSAR equation?
What is the purpose of QSAR equation?
- To calculate the log P value of a molecule
- To identify regions of a molecule that interact with hydrophobic regions in the binding site (correct)
- To determine the importance of a molecule's overall hydrophobicity
- To measure the overall hydrophobicity of a molecule
What is the value of π for the substituent CH3 in aliphatic substituents?
What is the value of π for the substituent CH3 in aliphatic substituents?
- 0.50 (correct)
- 1.68
- 0.52
- -1.16
What does a positive value of π imply about a substituent?
What does a positive value of π imply about a substituent?
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How is the logarithmic value of the partition coefficient (log P) related to π?
How is the logarithmic value of the partition coefficient (log P) related to π?
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What is the role of log P in a QSAR equation?
What is the role of log P in a QSAR equation?
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