6 Questions
What does the Hammett substituent constant (σ) measure?
The electron-withdrawing or electron-donating influence of substituents
What is the effect of an electron-withdrawing substituent on the equilibrium?
The equilibrium shifts to the right
Why are ortho values of σ invalid?
Due to steric factors
What is the effect of a para-substituent like NO2 on the dissociation constant?
It increases the dissociation constant
What is the effect of a meta-substituent like OH on the dissociation constant?
It decreases the dissociation constant
What is the relationship between the Hammett substituent constant and the activity of diethylphenylphosphates (insecticides)?
Electron-withdrawing substituents increase activity
Learn about the Hammett substituent constant (σ) in Quantitative Structure-Activity Relationships (QSAR). This quiz covers the measurement of σ, its significance, and applications. Understand the effects of electronic effects of substituents and more!
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