Antiparasitics

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Antiparasitic drugs by class

Cestodes = Albendazole, fenbendazole, oxfendazole, praziquantel Nematodes = Fenbendazole, ivermectin, milbemycin oxime, fenbendazole, ivermectin+praziquantel, pyrantel pamoate, selamectin Protozoa = Metronidazole, ponazuril, sulfadimethoxine, toltrazuril, ronidazole Ectoparasites = Lufenuron, lufenuron+mylbemycin oxime, spinosad, selamectin

Benzimidazoles

Albendazole, Febantel (drontal plus), Fenbendazole (panacur), Oxibendazole (anthelcide) (correct)

Pyrantel pamoate or tartrate (nemex)

Ivermectin, Milbemycin oxime (interceptor), Moxidectin (proheart), Selamectin (revolution)

Imidocarb hydrochloride, Metronidazole (flagyl), Ponazuril (marquis), Toltrazuril (baycox)

Tetrahydropyrimides

Pyrantel pamoate or tartrate (nemex) (correct)

Imidocarb hydrochloride, Metronidazole (flagyl), Ponazuril (marquis), Toltrazuril (baycox)

All of the above

Amitraz (mitaban), Epsiprantel (cestex), Lufenuron +milbemycin oxime (sentinel), Nitenpyram (capstar)

If an animals skin is exposed to an organophosphate care should be taken to remove the toxin from the skin and coat

True Signup and view all the answers

Macrocyclic lactones

Ivermectin, Milbemycin oxime (interceptor), Moxidectin (proheart), Selamectin (revolution) Signup and view all the answers

Antiprotozoals

Imidocarb hydrochloride, Metronidazole (flagyl), Ponazuril (marquis), Toltrazuril (baycox) Signup and view all the answers

Miscellaneous antiparasitics

Albendazole, Febantel (drontal plus), Fenbendazole (panacur), Oxibendazole (anthelcide) Signup and view all the answers

Primarily used to treat nematode and trematode infections. Working by inhibiting cellular division and the absorption of glucose by the parasites

Benzimidazoles, Signup and view all the answers

Prevent the activity of the neurotransmitter acetylcholine causing paralysis of the parasite

Tetrahydropyrinimides Signup and view all the answers

Inhibit actetylcholinesterase which inturn prevents transmission of acetylcholine, paralyzing the parasite and results in its death

Organophosphates Signup and view all the answers

Work with GABA neurotransmitters by attacking fluoride channels, causing paralysis, death and expulsion from the body

Macrocyclic lactones Signup and view all the answers

Used to treat a variety of protozoal diseases, killing or inhibiting the growth of the protozoa and preventing reproduction

Antiprotozoals Signup and view all the answers

Benzimidazole commonly used for intestinal helminth parasites and giardia (may cause bone toxicity such as leukopenia and thrombocytopenia)

Albendazole (valbazen) Signup and view all the answers

Benzimidazole commonly used for intestinal nematodes (do not give to pregnant animals)

Febantel (drontal plus) Signup and view all the answers

Benzimidazole commonly used for intestinal helminth parasites but may cause vomiting and diarrhea

Fenbendazole (panacur) Signup and view all the answers

Benzimidazole commonly used to treat nematodes in horses and dogs, do not give to dogs that might be infected with heartworm

Oxibendazole (anthelcide) Signup and view all the answers

Tetrahydropyrimidine commonly used to treat intestinal nematodes in horses, dogs, cats, and pigs

Pyrantel Signup and view all the answers

Suspensions of pyrantel should be kept out of direct sunlight because the drug can lose potency

True Signup and view all the answers

Macrocyclic lactone commonly used for heartworm prevention in dogs, and cats, treatment for intestinal helminths in dogs, nematode infections in horses, intestinal helminths and ectoparasites in cattle and pigs

Ivermectin (heartgard) Signup and view all the answers

Macrocyclic lactone commonly used as heartworm prevention, miticide/microfilaricide, also works on other nematodes, cannot be given to breeds susceptible to ivermectin toxicity

Milbemycin oxime (interceptor) Signup and view all the answers

Macrocyclic lactone commonly used for heartworm prevention in dogs, and nematodes in horses, cattle and pigs (cant give to breeds susceptible to ivermectin toxicity, dogs must test negative for heartworm before admin)

Moxidectin (proheart) Signup and view all the answers

Macrocyclic lactone commonly used for heartworm prevention in dogs and cats, ectoparasites in dogs, ectoparasites and nematodes in cats (can cause hair loss at the site of administration)

Selamectin (revolution) Signup and view all the answers

Antiprotozoal commonly used for tick borne pathogens, hemobartenollosis in cats and babesia canis infections (only for use in dogs and cats)

Imidocarb hydrochloride (imizol) Signup and view all the answers

Antiprotozoal commonly used as an antiprotozoal/antibacterial for dogs, cats, horses and cattle (can cause CNS toxicity; not for use in food animals)

Metronidazole (flagyl) Signup and view all the answers

Antiprotozoal commonly used for equine protozoal myeloencephalitis and other equine protozoal infections

Ponazuril (marquis) Signup and view all the answers

Miscellaneous antiparasitic not used anymore but that used to be for topical treatment of mites, particularly demodex in dogs (can cause sedative effects)

Amitraz (mitaban) Signup and view all the answers

Miscellaneous antiparasitic commonly used for protection against fleas heartworms and nematodes in dogs (high margin of safety)

Lufenuron +milbemycin oxime (sentinel) Signup and view all the answers

Miscellaneous antiparasitic used as a flea treatment for dogs and cats and may cause skin irritations

Nytenpyram (capstar) Signup and view all the answers