Psychopharmacology Interventions

What is the mechanism of action of Fluoxetine?

What is one of the approved indications for Fluoxetine?

What is a common side effect of Fluoxetine?

What is the domain of Fluoxetine?

What is the trade name of the drug Fluoxetine?

What is the effect of Fluoxetine on noradrenaline and dopamine levels?

What is the additional information that the clinician needs to know?

What is the biological target of Fluoxetine?

What is the primary focus of Domain 3 in the context of psychopharmacology?

What is the main role of vesicular transporters in neurotransmission?

What is the mechanism of action of G-protein coupled receptors?

Which of the following is NOT a biological target of psychoactive drugs?

What is the primary goal of the activity 'Educating yourself and your clients'?

What is the role of pharmacokinetics in psychopharmacology?

Which of the following is an example of a drug classification system?

What is the purpose of the 'Tutorial plan'?

Domain 3: Interventions

Knowledge of evidence-based interventions, including psychopharmacology, drug classification, pharmacokinetics, and pharmacodynamics
Pharmacokinetics involves what the body does to the drug, including absorption, distribution, metabolism, and excretion
Pharmacodynamics involves what the drug does to the body, including interaction with biological targets at the molecular level

Psychopharmacology

Two drug classification systems: Anatomical-Therapeutic-Chemical (ATC) and Mechanism of Action (NbN)
Biological targets of common psychoactive drugs include:
- Neurotransmitter transporters
- Vesicular transporters
- G-protein coupled receptors
- Enzymes
- Ion channels

Neurotransmitter Transporters

Inhibition of presynaptic transporters increases the availability of neurotransmitters in the synapse to bind with receptors on the post-synaptic neuron
Examples of transporter-based drugs include:
- Fluoxetine (Prozac, Fluotex)
  - Domain: Serotonin
  - Mechanism: Reuptake inhibitor
  - Approved indications: MDD, OCD, PTSD, Bulimia nervosa, Panic disorder, Trichotillomania
  - Efficacy and side effects: Improves symptoms of depression and anxiety, reduces compulsive behavior and obsessional thoughts, but may cause GI symptoms, anxiety, changes in sleep, and sexual dysfunction

Educating Yourself and Your Clients

Importance of building confidence in terminology and pharmacology
Resources for learning about psychopharmacology:
- https://go.drugbank.com/about
- https://nbn2r.com/
Framework for researching and educating clients about psychoactive drugs:
- Identify the domain and mechanism of action
- Identify the approved indications and potential efficacy and side effects
- Develop practical notes for clients and clinicians

This quiz tests your knowledge of evidence-based interventions, including psychopharmacology, drug classification, and pharmacokinetics. Prepare for your PSY5PPY exam with this tutorial.