Psychopharmacology: Antipsychotics and Antidepressants
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Questions and Answers

Which of the following medications belongs to the category of atypical antipsychotics?

  • Fluphenazine
  • Thiothixene
  • Olanzapine (correct)
  • Haloperidol
  • What is the primary route of administration for the selective serotonin reuptake inhibitors (SSRIs) listed?

  • Injection
  • Transdermal
  • Oral (correct)
  • Intranasal
  • Which medication is classified as a norepinephrine dopamine reuptake inhibitor (NDRI)?

  • Bupropion (correct)
  • Citalopram
  • Duloxetine
  • Sertraline
  • Which of the following medications is a tricyclic antidepressant (TCA)?

    <p>Amitriptyline</p> Signup and view all the answers

    What type of medication is Buspirone?

    <p>Nonbenzodiazepine anxiolytic</p> Signup and view all the answers

    Which mood stabilizer is also known as Lithobid?

    <p>Lithium carbonate</p> Signup and view all the answers

    Which of the following medications is indicated for use as an antidepressant?

    <p>Both B and C</p> Signup and view all the answers

    Which medication is known as an atypical antipsychotic and is primarily used to treat schizophrenia?

    <p>Clozapine</p> Signup and view all the answers

    What is the primary therapeutic effect of benzodiazepines?

    <p>Anxiolytic effects</p> Signup and view all the answers

    Which class of medications includes Lurasidone?

    <p>Atypical Antipsychotics</p> Signup and view all the answers

    Which medication is considered a serotonin and norepinephrine reuptake inhibitor (SNRI)?

    <p>Duloxetine</p> Signup and view all the answers

    What is the main function of mood stabilizers such as Lithium carbonate?

    <p>Regulating mood swings</p> Signup and view all the answers

    Which of the following medications is associated with the treatment of anxiety?

    <p>Alprazolam</p> Signup and view all the answers

    What is the route of administration for Fluoxetine?

    <p>Oral</p> Signup and view all the answers

    Which medication is primarily classified as a tricyclic antidepressant?

    <p>Imipramine</p> Signup and view all the answers

    Which medication would be categorized as a non-benzodiazepine anxiolytic?

    <p>Buspirone</p> Signup and view all the answers

    What is the role of antidepressants such as Trazodone?

    <p>To alleviate depression</p> Signup and view all the answers

    Which medication is known to affect norepinephrine and serotonin levels?

    <p>Mirtazapine</p> Signup and view all the answers

    Study Notes

    Typical Antipsychotics

    • Chlorpromazine (Thorazine), Fluphenazine, Haloperidol, Trifluoperazine, Thioridazine, Perphenazine, Thiothixene, and Pimozide
    • These medications are grouped under a category called typical antipsychotics

    Atypical Antipsychotics

    • Aripiprazole, Clozapine, Ziprasidone, Asenapine, Brexpiprazole, Risperidone, Lurasidone, Olanzapine, Quetiapine, Paliperidone, and Lumazaperone
    • These medications are grouped under a category called atypical antipsychotics

    Norepinephrine Dopamine Reuptake Inhibitors (NDRIs)

    • Bupropion is the only NDRI listed

    Selective Serotonin Reuptake Inhibitors (SSRIs)

    • Fluoxetine, Citalopram, Sertraline, Paroxetine, Fluvoxamine, and Escitalopram
    • All are administered orally

    Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs)

    • Venlafaxine and Duloxetine

    Tricyclic Antidepressants (TCAs)

    • Amitriptyline, Imipramine, Nortriptyline, Doxepin, Mirtazapine, and Amoxetine
    • These medications are grouped under a category called tricyclic antidepressants

    Antidepressants

    • Trazodone (Desyrel)

    Benzodiazepines

    • Chlordiazepoxide (Librium), Diazepam, Alprazolam, Clonazepam, and Lorazepam

    Nonbenzodiazepines

    • Buspirone

    Mood Stabilizers

    • Lithium carbonate (Lithane, Lithobid), Valproic acid, Carbamazepine, and Lamotrigine
    • These medications are used to treat mood disorders
    • They help stabilize moods

    Other Medications

    • Phenelzine sulfate, Isocarboxazid, Selegiline (Transdermal), Tranylcypromine, Zolpidem, and Ramelteon
    • These medications are commonly used for mental health conditions
    • Some medications are administered via routes including oral, injection, or transdermal.

    Antipsychotics

    • Typical Antipsychotics are older medications with a higher likelihood of causing extrapyramidal symptoms (EPS) like muscle stiffness, tremors, and akinesia.
      • Examples: Chlorpromazine (Thorazine), Fluphenazine, Haloperidol, Trifluoperazine, Thioridazine, Perphenazine, Thiothixene, Pimozide
    • Atypical Antipsychotics are newer medications with a lower risk of EPS, but they can cause metabolic side effects like weight gain, diabetes, and hyperlipidemia.
      • Examples: Aripiprazole, Clozapine, Ziprasidone, Asenapine, Brexpiprazole, Risperidone, Lurasidone, Olanzapine, Quetiapine, Paliperidone, Lumazaperone

    Antidepressants

    • Norepinephrine Dopamine Reuptake Inhibitors (NDRIs) are used to treat depression, smoking cessation, and ADHD.
      • Example: Bupropion
    • Selective Serotonin Reuptake Inhibitors (SSRIs) block the reuptake of serotonin in the brain, leading to an increase in serotonin levels and improved mood.
      • Examples: Fluoxetine, Citalopram, Sertraline, Paroxetine, Fluvoxamine, Escitalopram
    • Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs) block the reuptake of both serotonin and norepinephrine, leading to a synergistic effect on mood and energy.
      • Examples: Venlafaxine, Duloxetine
    • Tricyclic Antidepressants (TCAs) block the reuptake of serotonin and norepinephrine, but they can cause several side effects, including drowsiness, dry mouth, constipation, and blurred vision.
      • Examples: Amitriptyline, Imipramine, Nortriptyline, Doxepin, Mirtazapine, Amoxetine
    • Other Antidepressants:
      • Trazodone (Desyrel) is a unique antidepressant that can be used for insomnia and anxiety.

    Anxiolytics

    • Benzodiazepines are a class of medications used to treat anxiety, seizures, and insomnia. They work by enhancing the effects of GABA, a neurotransmitter that inhibits nerve activity.
      • Examples: Chlordiazepoxide (Librium), Diazepam, Alprazolam, Clonazepam, Lorazepam
    • Nonbenzodiazepines
      • Buspirone is a non-benzodiazepine anxiolytic, used to treat anxiety without causing sedation.

    Mood Stabilizers

    • Mood Stabilizers are used to treat bipolar disorder to prevent mood swings from mania to depression.
      • Examples: Lithium carbonate (Lithane, Lithobid), Valproic acid, Carbamazepine, Lamotrigine

    Other Medications

    • Monoamine Oxidase Inhibitors (MAOIs) are older antidepressants with a higher risk of side effects, but they can be effective for treating atypical depression.
      • Examples: Phenelzine sulfate, Isocarboxazid, Selegiline (Transdermal), Tranylcypromine
    • Hypnotics are medications used to treat insomnia.
      • Zolpidem and Ramelteon are examples of hypnotics.

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    Description

    This quiz covers different classes of psychotropic medications, including typical and atypical antipsychotics, norepinephrine dopamine reuptake inhibitors (NDRIs), selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake inhibitors (SNRIs), and tricyclic antidepressants (TCAs). Test your knowledge on these essential psychiatric drugs and their classifications.

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