PSYC1022: Topic 1 Origins of Addictive Drugs
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Questions and Answers

What is the primary effect of Depressants on the CNS?

  • Interfere with CNS signaling
  • Slow down CNS activity (correct)
  • Speed up CNS activity
  • Alter sensory perceptions
  • Which of the following is NOT a type of Depressant?

  • Cocaine (correct)
  • Codeine
  • Opium
  • Morphine
  • What is the classification of drugs based on?

  • Chemical composition
  • Physical appearance
  • Addictive potential
  • CNS effects (correct)
  • Which of the following is an example of a Hallucinogen?

    <p>None of the above</p> Signup and view all the answers

    What is the name of the topic that discusses the origins and manufacture of addictive drugs?

    <p>Topic 1: Origins &amp; Manufacture of addictive drugs</p> Signup and view all the answers

    Who is the instructor for the PSYC1022 course?

    <p>Dr. Helena Pacitti</p> Signup and view all the answers

    Where were ceramic bowls found in a sacred site, related to opium?

    <p>Brittany, France</p> Signup and view all the answers

    What is the name of the papyrus that mentioned a mixture of opium effective in calming crying children?

    <p>The Ebers papyrus</p> Signup and view all the answers

    When was morphine first isolated?

    <p>1803</p> Signup and view all the answers

    What percentage of the dry weight of opium is morphine?

    <p>~ 8 to 14%</p> Signup and view all the answers

    Who discovered that opium dissolved better in a solution of alcohol rather than water?

    <p>Paracelsus</p> Signup and view all the answers

    Who produced and promoted his own Laudanum recipe?

    <p>Thomas Sydenham</p> Signup and view all the answers

    What was Laudanum used for, according to the content?

    <p>A treatment for a range of medical conditions</p> Signup and view all the answers

    In which year did recreational use of opium appear in Homer’s ‘The Odyssey’?

    <p>700 BC</p> Signup and view all the answers

    What is a characteristic of 'others' in the context of substances?

    <p>They do not fit neatly into other categories.</p> Signup and view all the answers

    What is the approximate year of the oldest known site of wine production?

    <p>4100 BC</p> Signup and view all the answers

    What is the average amount of pure alcohol consumed per person per year in a high-consuming region?

    <p>6.2 litres</p> Signup and view all the answers

    What is the approximate percentage of unrecorded liquor worldwide?

    <p>25%</p> Signup and view all the answers

    What is the plant from which opium is derived?

    <p>Poppy</p> Signup and view all the answers

    What is the approximate time period during which opium was used broadly throughout Europe, Asia, Middle East, and North Africa?

    <p>10,000-2000 BC</p> Signup and view all the answers

    What is the approximate year of the oldest known evidence of opium burial in a ritual or sacred context?

    <p>4200 BC</p> Signup and view all the answers

    What is the approximate number of deaths worldwide attributed to alcohol consumption?

    <p>3.3 million</p> Signup and view all the answers

    What was the concentration of codeine in opium?

    <p>1-3%</p> Signup and view all the answers

    Who synthesized heroin in 1874?

    <p>Charles Wright</p> Signup and view all the answers

    What was the purpose of Laudanum, as available by prescription from 1837 to 1901?

    <p>Relieving pain and alleviating withdrawal in dependent babies</p> Signup and view all the answers

    Who named the synthesized compound 'heroin' in 1898?

    <p>Felix Hoffmann</p> Signup and view all the answers

    Why did Bayer cease production of heroin in 1913?

    <p>With the introduction of legislation to control the production and sale of such compounds</p> Signup and view all the answers

    What was the purpose of Mrs. Winslow's Soothing Syrup, as advertised in c. 1849?

    <p>Soothing children</p> Signup and view all the answers

    What was the addictive potential of codeine compared to morphine or heroin?

    <p>Lower than morphine or heroin</p> Signup and view all the answers

    What happened to the production and sale of addictive compounds, including Laudanum, from 1910 onwards?

    <p>They became more restricted due to laws</p> Signup and view all the answers

    Study Notes

    Drug Classifications

    • Classified into four categories based on CNS effects:
      • Depressants: slow down CNS activity
      • Stimulants: speed up CNS activity
      • Hallucinogens: alter sensory perceptions by interfering with CNS signaling
      • Others: do not fit neatly into other categories

    Depressants

    • Include alcohol, opium, morphine, laudanum, codeine, and heroin
    • Slow down CNS activity

    History of Alcohol

    • 7000-5800 BC: evidence of alcoholic liquid made from fermented rice, honey, and hawthorn found in Jiahu, China
    • 4100 BC: evidence of wine production found in Areni-1 cave, Armenia
    • 6.2 liters of pure alcohol per person consumed globally, with higher consumption in Europe, Russia, Australia, and Canada
    • 3.3 million deaths worldwide attributed to alcohol consumption

    History of Opium

    • Derived from the sap of the opium poppy
    • Historically used broadly throughout Europe, Asia, Middle East, and North Africa (10,000-2000 BC)
    • Used in ritual and sacred contexts in Brittany, France, and Southern Spain (4200 BC)
    • Used to calm crying children in Egypt, India, and Europe (1500 BC)

    History of Morphine

    • First isolated in 1803 by Friedrich Sertürner
    • Contains 8-14% of the dry weight of opium
    • Extraction method still used in illicit labs today

    History of Laudanum

    • Discovered by Paracelsus in 1493-1541
    • Popularized by Thomas Sydenham in 1624-1689
    • Available by prescription from 1837-1901 for pain relief and alleviating withdrawal
    • Production and sale restricted by laws from 1910 onwards

    History of Codeine

    • Present in opium at a concentration of 1-3%
    • Isolated by Pierre Robiquet in 1821
    • Used as an analgesic, antitussive, antidiarrheal, antihypertensive, antianxiety, sedative, and to suppress premature labor contractions

    History of Heroin

    • First synthesized by Charles Wright in 1874
    • Replicated by Felix Hoffmann in 1898
    • Marketed by Bayer as an effective sedative for coughs without morphine's addictive potential, leading to widespread dependence
    • Production ceased by Bayer in 1913 with the introduction of legislation to control production and sale

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    Description

    This quiz covers the origins and manufacture of addictive drugs, including drug classifications and examples of depressants such as alcohol and opium.

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