PSY1BNA Lecture 4: Resting Membrane Potential
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Questions and Answers

What is the primary function of the sodium-potassium pump in a neuron?

  • To maintain the resting membrane potential (correct)
  • To open potassium channels
  • To generate action potential
  • To facilitate synaptic transmission

What is the main problem that neurons solve using electrical signals?

  • Conducting information over a long distance (correct)
  • Generating action potential
  • Facilitating synaptic transmission
  • Conducting information over a short distance

What determines the distribution of ions inside and outside of a neuron at rest?

  • Electrostatic pressure and diffusion (correct)
  • The action potential and neural integration
  • Neurotransmitter synthesis and synaptic transmission
  • Electrochemical forces and the sodium-potassium pump

What is the role of potassium channels in the resting membrane potential?

<p>To allow the efflux of potassium ions (A)</p> Signup and view all the answers

What is the resulting effect of electrochemical forces on the neural membrane?

<p>An electrochemical gradient (A)</p> Signup and view all the answers

What is the primary carrier of electrical charge in the cytosol of the axon?

<p>Electrically charged atoms → ions (A)</p> Signup and view all the answers

What is the main component of the fluid inside cytosol and extracellular fluid?

<p>Water (H₂O) (C)</p> Signup and view all the answers

What type of bond is formed between hydrogen and oxygen atoms in a water molecule?

<p>Covalent bond (B)</p> Signup and view all the answers

What is the term for ions with a positive charge?

<p>Cations (B)</p> Signup and view all the answers

What is the function of membrane proteins in the phospholipid bilayer?

<p>To assemble into pores and ion channels (B)</p> Signup and view all the answers

What is the term for molecules that are attracted to water?

<p>Hydrophilic (C)</p> Signup and view all the answers

What is the energy source utilized by ion pumps to transport ions across the bilayer?

<p>ATP breakdown (B)</p> Signup and view all the answers

What is the ratio of K⁺ to A⁻ when the microelectrode records no potential difference (Vm=0)?

<p>1:1 (A)</p> Signup and view all the answers

What happens to the inside of the membrane when potassium ions (K⁺) move out of the cell?

<p>It becomes more negatively charged (D)</p> Signup and view all the answers

What is the equilibrium potential of potassium ions (K⁺) approximately equal to?

<p>-80mV (A)</p> Signup and view all the answers

What is the primary reason for the net movement of ions across the membrane?

<p>The difference between the membrane potential and the equilibrium potential (A)</p> Signup and view all the answers

What is the result of a small change in ionic concentrations on the membrane potential?

<p>A large change in membrane potential (A)</p> Signup and view all the answers

What is the term for the ability of the membrane to store electrical charge?

<p>Capacitance (C)</p> Signup and view all the answers

What is a characteristic of K⁺ channels?

<p>They are selectively permeable to K⁺ (B)</p> Signup and view all the answers

What is required for a net movement of ions across the membrane through open channels?

<p>Both open channels and a concentration gradient (A)</p> Signup and view all the answers

What is the result of diffusion in a solution?

<p>Particles are distributed evenly throughout the solution (B)</p> Signup and view all the answers

What is the driving force behind the movement of ions from regions of high concentration to low concentration?

<p>Diffusion (C)</p> Signup and view all the answers

What is the term for the difference in concentration of ions between two regions?

<p>Concentration gradient (B)</p> Signup and view all the answers

What can induce a net flow of ions in a solution?

<p>Electric fields (B)</p> Signup and view all the answers

What is the ionic driving force for a particular ion?

<p>Vm - Eion (B)</p> Signup and view all the answers

What is the purpose of the ion pumps in the neuronal membrane?

<p>To transport ions across the membrane against their concentration gradient (A)</p> Signup and view all the answers

What would happen to the membrane potential if the extracellular K+ concentration increases?

<p>The membrane potential would become less negative (C)</p> Signup and view all the answers

What is the Goldman equation used for?

<p>To calculate the resting membrane potential (D)</p> Signup and view all the answers

What is the role of the sodium-potassium pump in neuronal signaling?

<p>To transport Na+ and Ca2+ ions out of the neuron (A)</p> Signup and view all the answers

What is the effect of a mutation in a specific K+ channel on the neuronal function?

<p>It can lead to inherited neurological disorders (B)</p> Signup and view all the answers

What is the role of the blood-brain barrier in regulating the concentration of K+ ions?

<p>It helps to regulate the concentration of K+ ions in the extracellular space (D)</p> Signup and view all the answers

What is the function of the pore-loop in potassium channels?

<p>It contributes to the selective filter that makes the channel permeable mostly to K+ (D)</p> Signup and view all the answers

What is the resting membrane potential close to?

<p>The equilibrium potential for K+ (A)</p> Signup and view all the answers

What is the consequence of the differential concentrations of ions inside and outside the neuron and the semipermeable nature of the membrane?

<p>The resting membrane potential (D)</p> Signup and view all the answers

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