22 Questions
What is the main function of transferrin?
To transport iron
Which of the following is a characteristic of IgG?
It can cross the placenta
What is the name of the protein that is increased in tissue necrosis, rheumatic fever, and infections?
C-reactive protein (CRP)
Which of the following is a characteristic of IgA?
It is increased after birth
What is the name of the disease that is associated with an increase in IgG, IgA, or IgM?
Multiple myeloma
Which of the following is decreased in infections, liver disease, and nephrotic syndrome?
Transferrin
What is the name of the class of immunoglobulins that cannot cross the placenta?
IgM
Which of the following immunoglobulins is increased in allergies, asthma, and hay fever?
IgE
What is the significance of increased fetal fibronectin in cervicovaginal secretions?
It indicates a risk of premature birth
What is the principle behind refractometry for serum total protein analysis?
Measures the change in velocity of light as it passes through a medium
What is the basis of the biuret method for protein analysis?
Formation of a purple-colored complex between cupric ions and peptide bonds
Which of the following immunoglobulins is increased in liver disorders and infections?
IgD
What is the significance of decreased immunoglobulin levels?
It is associated with increased risk of infections
What is the significance of increased levels of immunoglobulins in Waldenstrom macroglobulinemia?
It is a sign of cancer
What is the result of protein binding to a dye in the dye binding technique?
A shift of the maximum absorbance of the dye
What is the basis of the Kjeldahl technique for protein quantification?
Quantification of nitrogen content
What is the net charge of serum proteins in serum protein electrophoresis?
Negative
Which protein travels the farthest in serum protein electrophoresis?
Albumin
What is the pH of the buffer used in serum protein electrophoresis?
8.6
Why is the Kjeldahl technique not used in routine testing?
It is too cumbersome
What is the relationship between protein concentration and absorbance in the dye binding technique?
Direct proportion
What is the purpose of the biuret method in relation to the Kjeldahl technique?
To be validated by the Kjeldahl technique
Identify and learn about the different proteins found in human blood, including Transferrin, C-Reactive Protein, and Immunoglobulins. Understand their functions and changes in various disorders and conditions.
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