Proteins in Human Blood

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What is the main function of transferrin?

To increase in response to infections

To synthesize immunoglobulins

To transport iron (correct)

To act as an acute-phase reactant

Which of the following is a characteristic of IgG?

It cannot cross the placenta

It is increased in response to rheumatic fever

It can cross the placenta (correct)

It is decreased in liver disorders

What is the name of the protein that is increased in tissue necrosis, rheumatic fever, and infections?

Immunoglobulin

IgM

C-reactive protein (CRP) (correct)

Transferrin

Which of the following is a characteristic of IgA?

It is increased after birth Signup and view all the answers

What is the name of the disease that is associated with an increase in IgG, IgA, or IgM?

Multiple myeloma Signup and view all the answers

Which of the following is decreased in infections, liver disease, and nephrotic syndrome?

Transferrin Signup and view all the answers

What is the name of the class of immunoglobulins that cannot cross the placenta?

IgM Signup and view all the answers

Which of the following immunoglobulins is increased in allergies, asthma, and hay fever?

IgE Signup and view all the answers

What is the significance of increased fetal fibronectin in cervicovaginal secretions?

It indicates a risk of premature birth Signup and view all the answers

What is the principle behind refractometry for serum total protein analysis?

Measures the change in velocity of light as it passes through a medium Signup and view all the answers

What is the basis of the biuret method for protein analysis?

Formation of a purple-colored complex between cupric ions and peptide bonds Signup and view all the answers

Which of the following immunoglobulins is increased in liver disorders and infections?

IgD Signup and view all the answers

What is the significance of decreased immunoglobulin levels?

It is associated with increased risk of infections Signup and view all the answers

What is the significance of increased levels of immunoglobulins in Waldenstrom macroglobulinemia?

It is a sign of cancer Signup and view all the answers

What is the result of protein binding to a dye in the dye binding technique?

A shift of the maximum absorbance of the dye Signup and view all the answers

What is the basis of the Kjeldahl technique for protein quantification?

Quantification of nitrogen content Signup and view all the answers

What is the net charge of serum proteins in serum protein electrophoresis?

Negative Signup and view all the answers

Which protein travels the farthest in serum protein electrophoresis?

Albumin Signup and view all the answers

What is the pH of the buffer used in serum protein electrophoresis?

8.6 Signup and view all the answers

Why is the Kjeldahl technique not used in routine testing?

It is too cumbersome Signup and view all the answers

What is the relationship between protein concentration and absorbance in the dye binding technique?

Direct proportion Signup and view all the answers

What is the purpose of the biuret method in relation to the Kjeldahl technique?

To be validated by the Kjeldahl technique Signup and view all the answers