5 Questions
Which of the following statements about signal sequences is true?
Signal sequences are both necessary and sufficient for protein targeting
What happens when the N-terminal ER signal sequence is placed at the beginning of a cytosolic protein?
The protein is targeted to the ER
What is the effect of removing or mutating the signal sequence of an ER protein?
The protein is retained in the cytosol
What is the importance of physical properties, such as hydrophobicity, in the signal-recognition process?
Physical properties are more important than the exact amino acid sequence
Are signal sequences of proteins having the same destination functionally interchangeable?
Yes, their amino acid sequences can vary greatly
Test your knowledge on protein targeting and signal sequences in this quiz. Explore how genetic engineering techniques can transfer peptides between proteins and the impact of signal sequence manipulation on protein localization.
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