Protein Targeting and Signal Sequences Quiz
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Questions and Answers

Which of the following statements about signal sequences is true?

  • Signal sequences are only found in proteins that are targeted to the cytosol
  • Signal sequences are both necessary and sufficient for protein targeting (correct)
  • Signal sequences have the same amino acid sequence in all proteins
  • Signal sequences are not necessary for protein targeting

    • What happens when the N-terminal ER signal sequence is placed at the beginning of a cytosolic protein?

  • The protein is not affected
  • The protein is targeted to the ER (correct)
  • The protein is retained in the cytosol
  • The protein is targeted to the cytosol

    • What is the effect of removing or mutating the signal sequence of an ER protein?

  • The protein is not affected
  • The protein is retained in the cytosol (correct)
  • The protein is targeted to the ER
  • The protein is targeted to the cytosol

    • What is the importance of physical properties, such as hydrophobicity, in the signal-recognition process?

    <p>Physical properties are more important than the exact amino acid sequence</p> Signup and view all the answers

    Are signal sequences of proteins having the same destination functionally interchangeable?

    <p>Yes, their amino acid sequences can vary greatly</p> Signup and view all the answers

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