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Questions and Answers
Which of the following statements about signal sequences is true?
Which of the following statements about signal sequences is true?
- Signal sequences are only found in proteins that are targeted to the cytosol
- Signal sequences are both necessary and sufficient for protein targeting (correct)
- Signal sequences have the same amino acid sequence in all proteins
- Signal sequences are not necessary for protein targeting
What happens when the N-terminal ER signal sequence is placed at the beginning of a cytosolic protein?
What happens when the N-terminal ER signal sequence is placed at the beginning of a cytosolic protein?
- The protein is not affected
- The protein is targeted to the ER (correct)
- The protein is retained in the cytosol
- The protein is targeted to the cytosol
What is the effect of removing or mutating the signal sequence of an ER protein?
What is the effect of removing or mutating the signal sequence of an ER protein?
- The protein is not affected
- The protein is retained in the cytosol (correct)
- The protein is targeted to the ER
- The protein is targeted to the cytosol
What is the importance of physical properties, such as hydrophobicity, in the signal-recognition process?
What is the importance of physical properties, such as hydrophobicity, in the signal-recognition process?
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Are signal sequences of proteins having the same destination functionally interchangeable?
Are signal sequences of proteins having the same destination functionally interchangeable?
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