Protein Synthesis: Ribosome Functions and Translation Process
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Questions and Answers

What is the main function of the small subunit of a ribosome?

  • Binds fMet-tRNA in the P site
  • Binds to the Shine-Dalgarno sequence (correct)
  • Binds to the 5' cap of mRNA
  • Has peptidyl transferase activity

Which of the following is true about the large subunit of a ribosome?

  • Scans the mRNA for the first AUG codon
  • Contains the E, P, and A tRNA binding sites (correct)
  • It binds to the mRNA cap structure
  • It carries formylated methionine (fMet)

During the termination phase of translation, what binds to the stop codons?

  • Normal tRNAs
  • fMet-tRNA
  • Release factors (correct)
  • Initiator tRNA

What is the function of fMet in translation initiation in bacteria?

<p>Forming a complex with small ribosomal subunit (C)</p> Signup and view all the answers

Which site on the large subunit of a ribosome is responsible for holding the growing polypeptide chain?

<p>P site (C)</p> Signup and view all the answers

What does the small ribosomal subunit initially bind to during translation initiation?

<p>Shine-Dalgarno sequence (A)</p> Signup and view all the answers

Which of the following is a characteristic of the termination stage of polypeptide synthesis?

<p>Recognition of nonsense codons (A)</p> Signup and view all the answers

What is the role of release factors in the termination stage of polypeptide synthesis?

<p>Halting polypeptide synthesis (A)</p> Signup and view all the answers

Which type of mutations occur more frequently: Transition or Transversion mutations?

<p>Transition mutations (D)</p> Signup and view all the answers

What are the possible forms that mutations can take?

<p>Substitutions (D)</p> Signup and view all the answers

What is the difference between synonymous and non-synonymous mutations?

<p>Non-synonymous mutations don't alter amino acids (C)</p> Signup and view all the answers

In the cell cycle, what is the specific relationship between DNA replication and metabolism?

<p>Metabolism influences DNA replication (B)</p> Signup and view all the answers

In the three levels of tRNA structure, the tertiary structure is represented by which shape?

<p>T shape (B)</p> Signup and view all the answers

What is the function of transfer RNAs (tRNAs) in translation?

<p>Translate mRNA codons to amino acids (A)</p> Signup and view all the answers

Which component of tRNA carries a specific amino acid and base pairs with mRNA codons?

<p>Anticodon (A)</p> Signup and view all the answers

What phenomenon is described by the term 'codon wobble' in relation to tRNAs?

<p>Recognition of multiple codons by a single tRNA (C)</p> Signup and view all the answers

Which component of tRNA forms the secondary structure resembling a cloverleaf shape?

<p>Anticodon loop (C)</p> Signup and view all the answers

What is the role of ribosomes in translation?

<p>Mediating the assembly of amino acids into proteins (A)</p> Signup and view all the answers

How many subunits make up a ribosome?

<p>2 (C)</p> Signup and view all the answers

During the initiation phase of translation, what binds to the start codon on mRNA to signify the beginning of translation?

<p>'Start' codon (C)</p> Signup and view all the answers

'A specific tRNA is covalently coupled to a specific amino acid', highlighting this statement reflects which concept?

<p>'One tRNA, one amino acid' (B)</p> Signup and view all the answers

'Base pairing between mRNA codon and tRNA anticodon determines which amino acid is added to growing polypeptide.' This process primarily occurs during:

<p>Translation (D)</p> Signup and view all the answers

What is the role of introns in the context of translation?

<p>Removed during RNA splicing (D)</p> Signup and view all the answers

What is the function of the acceptor stem in tRNA molecules?

<p>Carry the amino acid (B)</p> Signup and view all the answers

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