20 Questions
What is the role of Glycosyltransferase enzymes in protein modification?
They transfer monosaccharides from an activated donor substrate to an appropriate acceptor in an oligosaccharide under construction
What is the function of the signal peptidase enzyme in the ER?
It removes the signal peptide from proteins after they enter the ER lumen
What can carbohydrate moieties act as in protein modification?
Recognition signals directing protein interactions and targeting
Where does the synthesis of a protein get completed after glycosylation and proteolytic processing?
In the RER (endoplasmic reticulum)
What is the role of the signal peptide in protein synthesis?
To halt the translation by binding with the SRP
Which molecule recognizes and binds to the signal peptide during protein synthesis?
Signal Recognition Particle (SRP)
What happens to the ribosome when the SRP binds to the signal peptide?
It becomes membrane-bound
What is the function of glycosylation in protein targeting?
To add sugar or carbohydrate moiety to the peptide chain
Which part of the signal peptide serves as a cleavage site for signal peptide excision?
C-region
What is the role of the SRP receptor at the RER membrane during protein synthesis?
To bind docking protein
What is the role of the Signal Recognition Particle (SRP) in protein synthesis?
It binds the signal peptide and halts the translation
What is the function of the Translocon in protein synthesis?
It facilitates the movement of ribosome to the cytoplasmic surface of ER
What is the role of the Signal Peptide in protein synthesis?
It is involved in arresting (halting) the translation process
What is the role of Glycosylation in protein targeting?
It adds sugar or carbohydrate moiety to the peptide chain producing glycoproteins
What happens when SRP binds to the signal peptide during protein synthesis?
Translation process is halted
What is the role of Glycosyltransferase enzymes in protein modification?
They transfer monosaccharides from an activated donor to an acceptor in an oligosaccharide under construction
Where does the peptide synthesis continue after the oligosaccharide is transferred to the peptide chain?
In the endoplasmic reticulum (ER)
What happens to the signal peptide after it is recognized and bound during protein synthesis?
It is cleaved by a signal peptidase enzyme
What is the function of the carbohydrate moieties in protein modification?
Direct protein interactions and targeting
What is the role of proteolytic processing in the endoplasmic reticulum (ER)?
Modifying the stability and solubility of the protein
Test your knowledge of protein synthesis and signal peptide biology with this quiz. Explore the process of protein synthesis starting at a free ribosome, the composition of the signal peptide, and its functions in the cell.
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