Protein Synthesis and Signal Peptide Quiz
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Questions and Answers

What is the role of Glycosyltransferase enzymes in protein modification?

  • They are involved in the removal of signal peptides from proteins
  • They break down proteins into smaller peptide chains
  • They facilitate the transfer of proteins from the ER lumen to the cytoplasm
  • They transfer monosaccharides from an activated donor substrate to an appropriate acceptor in an oligosaccharide under construction (correct)

    • What is the function of the signal peptidase enzyme in the ER?

  • It breaks down proteins into monosaccharides
  • It synthesizes proteins in the ER lumen
  • It removes the signal peptide from proteins after they enter the ER lumen (correct)
  • It adds a signal peptide to proteins before they enter the ER lumen

    • What can carbohydrate moieties act as in protein modification?

  • Catalysts for protein breakdown
  • Blocking agents for protein synthesis
  • Regulators of ribosome function
  • Recognition signals directing protein interactions and targeting (correct)

    • Where does the synthesis of a protein get completed after glycosylation and proteolytic processing?

    <p>In the RER (endoplasmic reticulum)</p> Signup and view all the answers

    What is the role of the signal peptide in protein synthesis?

    <p>To halt the translation by binding with the SRP</p> Signup and view all the answers

    Which molecule recognizes and binds to the signal peptide during protein synthesis?

    <p>Signal Recognition Particle (SRP)</p> Signup and view all the answers

    What happens to the ribosome when the SRP binds to the signal peptide?

    <p>It becomes membrane-bound</p> Signup and view all the answers

    What is the function of glycosylation in protein targeting?

    <p>To add sugar or carbohydrate moiety to the peptide chain</p> Signup and view all the answers

    Which part of the signal peptide serves as a cleavage site for signal peptide excision?

    <p>C-region</p> Signup and view all the answers

    What is the role of the SRP receptor at the RER membrane during protein synthesis?

    <p>To bind docking protein</p> Signup and view all the answers

    What is the role of the Signal Recognition Particle (SRP) in protein synthesis?

    <p>It binds the signal peptide and halts the translation</p> Signup and view all the answers

    What is the function of the Translocon in protein synthesis?

    <p>It facilitates the movement of ribosome to the cytoplasmic surface of ER</p> Signup and view all the answers

    What is the role of the Signal Peptide in protein synthesis?

    <p>It is involved in arresting (halting) the translation process</p> Signup and view all the answers

    What is the role of Glycosylation in protein targeting?

    <p>It adds sugar or carbohydrate moiety to the peptide chain producing glycoproteins</p> Signup and view all the answers

    What happens when SRP binds to the signal peptide during protein synthesis?

    <p>Translation process is halted</p> Signup and view all the answers

    What is the role of Glycosyltransferase enzymes in protein modification?

    <p>They transfer monosaccharides from an activated donor to an acceptor in an oligosaccharide under construction</p> Signup and view all the answers

    Where does the peptide synthesis continue after the oligosaccharide is transferred to the peptide chain?

    <p>In the endoplasmic reticulum (ER)</p> Signup and view all the answers

    What happens to the signal peptide after it is recognized and bound during protein synthesis?

    <p>It is cleaved by a signal peptidase enzyme</p> Signup and view all the answers

    What is the function of the carbohydrate moieties in protein modification?

    <p>Direct protein interactions and targeting</p> Signup and view all the answers

    What is the role of proteolytic processing in the endoplasmic reticulum (ER)?

    <p>Modifying the stability and solubility of the protein</p> Signup and view all the answers

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