Prostate Health Medications Overview
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Questions and Answers

What is a key component of the watchful waiting approach?

  • Regular reassessment at intervals (correct)
  • Daily medication administration
  • Immediate surgical intervention
  • Permanent lifestyle changes

How often are patients reassessed under a watchful waiting strategy?

  • Every month
  • Once a year
  • Every 6–12 months (correct)
  • Every 3 months

What type of education is emphasized for patients in the watchful waiting approach?

  • Surgical options available
  • Emergency procedures
  • Pharmaceutical treatments
  • Behavior modification techniques (correct)

What is NOT part of the watchful waiting approach?

<p>Immediate aggressive treatment (C)</p> Signup and view all the answers

Which statement best describes the watchful waiting strategy?

<p>Patients are assessed periodically with a focus on lifestyle changes. (B)</p> Signup and view all the answers

What is the recommended prostate gland size for symptomatic patients to consider treatment?

<p>40 g or more (B)</p> Signup and view all the answers

At what PSA level should treatment considerations begin for symptomatic patients?

<p>1.4 ng/mL (B)</p> Signup and view all the answers

Which treatment may be considered for patients with both erectile dysfunction and BPH?

<p>Monotherapy with a phosphodiesterase inhibitor or combination with an α-adrenergic antagonist (D)</p> Signup and view all the answers

What is the primary condition that phosphodiesterase inhibitors are used to address in this context?

<p>Erectile dysfunction (D)</p> Signup and view all the answers

Which option is NOT a consideration when treating symptomatic patients with prostate enlargement?

<p>Age of the patient (A)</p> Signup and view all the answers

Which of the following agents is NOT indicated for treating storage symptoms?

<p>Ibuprofen (C)</p> Signup and view all the answers

Which of these agents is primarily used for treating irritative voiding symptoms?

<p>Oxybutynin (D)</p> Signup and view all the answers

Which combination includes only agents that treat storage symptoms?

<p>Solifenacin, Propiverine, Trospium (A)</p> Signup and view all the answers

Which of the following agents is a selective muscarinic receptor antagonist used for storage symptoms?

<p>All of the above (D)</p> Signup and view all the answers

What is the primary reason Tadalafil is preferred over other phosphodiesterase inhibitors?

<p>It has a longer plasma half-life. (A)</p> Signup and view all the answers

Which agent is least likely to be used for treating irritative voiding symptoms?

<p>Amoxicillin (B)</p> Signup and view all the answers

How does Tadalafil affect voiding symptoms?

<p>It improves voiding symptoms. (B)</p> Signup and view all the answers

Which effect does Tadalafil NOT have according to the information provided?

<p>Reduces post-void residual urine volume. (A), Increases urinary flow rate. (D)</p> Signup and view all the answers

What outcome is associated with Tadalafil's use in patients?

<p>Improved voiding symptoms without changing urinary flow. (B)</p> Signup and view all the answers

In what context is Tadalafil particularly advantageous?

<p>In chronic diseases due to its long half-life. (D)</p> Signup and view all the answers

What is the primary action of phosphodiesterase inhibitors on smooth muscle tone?

<p>They reduce smooth muscle tone. (B)</p> Signup and view all the answers

What intracellular molecule do phosphodiesterase inhibitors increase?

<p>Cyclic guanosine monophosphate (B)</p> Signup and view all the answers

Which of the following areas is affected by the action of phosphodiesterase inhibitors?

<p>Detrusor muscle (C)</p> Signup and view all the answers

How do phosphodiesterase inhibitors affect the prostate?

<p>They relax smooth muscle in the prostate. (B)</p> Signup and view all the answers

What effect do phosphodiesterase inhibitors have on cyclic guanosine monophosphate levels?

<p>They increase cyclic guanosine monophosphate levels. (B)</p> Signup and view all the answers

Study Notes

Watchful Waiting

  • Patients with a prostate gland more than 40g and PSA of 1.4 ng/mL or more are reassessed every 6-12 months
  • Patients are educated about behavior modification
  • Consider using a phosphodiesterase inhibitor (PI) alone or in combination with an α-adrenergic antagonist if erectile dysfunction and BPH are present

Phosphodiesterase Inhibitors

  • Increase intracellular cyclic guanosine monophosphate
  • Relax smooth muscle of the detrusor, prostate, and urethra
  • Tadalafil is preferred due to its longer plasma half-life
  • Improves voiding symptoms but does not increase urinary flow rate or reduce PVR urine volume

Other Medications for Storage Symptoms

  • Darifenacin, fesoterodine, oxybutynin, propiverine, solifenacin, tolterodine and trospium are available to treat storage symptoms (irritative voiding symptoms)

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Description

This quiz covers the management of prostate health, focusing on watchful waiting strategies, the use of phosphodiesterase inhibitors, and other medications for storage symptoms. Learn about patient assessments, behavioral modifications, and the pharmacological treatments available for benign prostatic hyperplasia (BPH) and related symptoms.

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