Prostate Health and Cancer Quiz
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Questions and Answers

What is the primary function of the prostate gland?

  • To help make semen (correct)
  • To filter blood
  • To regulate testosterone levels
  • To produce urine

Which of the following symptoms is NOT typically associated with advanced prostate cancer?

  • Straining while you pee
  • Increased urgency to pee
  • Severe abdominal pain (correct)
  • Blood in the urine

What is one limitation of the PSA test for diagnosing prostate cancer?

  • It is accurate only in younger men
  • It requires direct biopsy for accurate results
  • It can only detect advanced cancer stages
  • Cancer may exist without elevated PSA levels (correct)

At what age does the likelihood of developing an enlarged prostate significantly increase?

<p>Over 50 (B)</p> Signup and view all the answers

Which condition is most common in younger adults and is categorized as non-cancerous?

<p>Prostatitis (B)</p> Signup and view all the answers

Which imaging method is considered one of the ways to test for prostate cancer?

<p>MRI (A)</p> Signup and view all the answers

What does the prostate-specific antigen (PSA) test measure?

<p>Prostate-specific antigen in the bloodstream (B)</p> Signup and view all the answers

What is the PSA threshold for men aged 50–59?

<p>More than 3.5 micrograms/L (D)</p> Signup and view all the answers

Which of the following is a benefit of PSA testing?

<p>Early detection before symptoms develop (D)</p> Signup and view all the answers

What is the purpose of active surveillance in prostate cancer treatment?

<p>To monitor localized prostate cancer until intervention is necessary (B)</p> Signup and view all the answers

What is a common risk associated with false-positive PSA tests?

<p>Unnecessary biopsies and stress (A)</p> Signup and view all the answers

In men aged 60–69, what is the PSA threshold that indicates further investigation?

<p>More than 4.5 micrograms/L (B)</p> Signup and view all the answers

Which of the following describes radical prostatectomy?

<p>A surgical removal of the prostate gland and lymph nodes (D)</p> Signup and view all the answers

What does watchful waiting aim to achieve in prostate cancer management?

<p>Deferring hormone therapy for non-symptomatic patients (C)</p> Signup and view all the answers

What type of radiotherapy is brachytherapy?

<p>Radiotherapy involving the implantation of radioactive sources (B)</p> Signup and view all the answers

Which of the following statements about false-negative PSA tests is accurate?

<p>They occur in about 15% of normal PSA results. (C)</p> Signup and view all the answers

Which of the following is a symptom associated with phosphodiesterase-5 inhibitors?

<p>Painful erection lasting for hours (D)</p> Signup and view all the answers

What is true regarding the onset of male pattern baldness?

<p>The age of onset is usually between 20-25 years. (D)</p> Signup and view all the answers

Which of the following is NOT a common cause of temporary hair loss?

<p>Inherited genetic traits (C)</p> Signup and view all the answers

What hormonal change is primarily responsible for male pattern baldness?

<p>Conversion of testosterone to dihydrotestosterone (D)</p> Signup and view all the answers

Which symptom indicates an adverse reaction to alpha blockers?

<p>Decreased sexual drive (C)</p> Signup and view all the answers

Which of the following is NOT a contraindication for medication use?

<p>Benign Prostate Hyperplasia (C)</p> Signup and view all the answers

Which lifestyle change is suggested to help manage symptoms of benign prostatic hyperplasia?

<p>Exercising pelvic floor muscles (B)</p> Signup and view all the answers

Which medication class is specifically aimed at shrinking the prostate or preventing its growth?

<p>5-alpha reductase inhibitors (C)</p> Signup and view all the answers

What is a common symptom of benign prostatic hyperplasia?

<p>Urinary retention (C)</p> Signup and view all the answers

Which factor is NOT associated with an increased risk for developing benign prostatic hyperplasia?

<p>History of urinary tract infections (D)</p> Signup and view all the answers

Which combination of medications is mentioned as potentially effective for managing overactive bladder symptoms?

<p>Alpha blockers and antimuscarinics (D)</p> Signup and view all the answers

Why might reducing intake of caffeinated beverages be recommended for men with benign prostatic hyperplasia?

<p>Caffeine can aggravate urinary symptoms (A)</p> Signup and view all the answers

Which of the following conditions should NOT lead to immediate medical intervention before treatment for benign prostatic hyperplasia?

<p>Recent cardiovascular surgery (A)</p> Signup and view all the answers

What outcome can be achieved by using combination medications for treating benign prostatic hyperplasia?

<p>Improved urinary flow and quality of life (D)</p> Signup and view all the answers

What treatment is appropriate for hormone-relapsed metastatic prostate cancer?

<p>Chemotherapy such as Docetaxel with prednisolone (D)</p> Signup and view all the answers

Which of the following is an effect of androgen deprivation therapy?

<p>Change in body shape and weight gain (A)</p> Signup and view all the answers

Which treatment method uses permanently implanted radioactive seeds?

<p>Low-dose rate brachytherapy (D)</p> Signup and view all the answers

What type of drugs are bisphosphonates, and what do they primarily inhibit?

<p>Calcium-regulated drugs that inhibit bone resorption (B)</p> Signup and view all the answers

What is the persistent condition referred to as erectile dysfunction?

<p>The inability to maintain an erection sufficient for satisfactory performance (C)</p> Signup and view all the answers

Which of the following symptoms should be monitored as complications of prostate cancer treatment?

<p>Pain and lower urinary tract symptoms (C)</p> Signup and view all the answers

Which type of hormone therapy acts by lowering testosterone levels?

<p>LHRH antagonists (B)</p> Signup and view all the answers

What should be done when there is evidence of significant disease progression in prostate cancer?

<p>Refer to a urological cancer specialist (A)</p> Signup and view all the answers

Which adverse effect commonly results from treatment with androgen deprivation therapy?

<p>Hot flushes and tiredness (A)</p> Signup and view all the answers

What is the recommended treatment for individuals undergoing androgen deprivation therapy with osteoporosis?

<p>Bisphosphonates to prevent bone loss (A)</p> Signup and view all the answers

Flashcards

Prostate

A gland shaped like a walnut, located below the bladder and surrounding the urethra. It produces semen, the fluid that carries sperm.

Prostate Cancer

A condition where cells in the prostate grow uncontrollably, leading to abnormal growths. It can affect urination and potentially cause pain.

Enlarged Prostate

A common condition in men over 50 where the prostate grows larger, affecting urination.

Symptoms of Enlarged Prostate

Increased urgency to urinate, straining during urination, feeling like the bladder hasn't emptied completely, and blood in the urine.

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Prostatitis

Inflammation of the prostate, occurring in men of all ages. It affects urination and causes discomfort.

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PSA Test

A blood test that measures Prostate-specific Antigen (PSA) levels. Used as a preliminary screening for prostate cancer.

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PSA Test Limitations

PSA levels can increase due to conditions other than cancer (like benign prostatic enlargement or infection). Elevated PSA alone doesn't confirm cancer.

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PSA Threshold

The PSA level that indicates a need for further investigation, depending on age.

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Benefits of PSA Testing

Early detection and treatment of prostate cancer, potentially extending life or achieving a complete cure.

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Limitations of PSA Testing

False-negative results (missing cancer) and false-positive results (unnecessary worry) are possible.

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Watchful Waiting

Monitoring prostate cancer without immediate treatment, suitable for localized cancer and those not suitable for or not desiring treatment.

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Active Surveillance

Regularly monitoring prostate cancer with potential for radical treatment if the tumor progresses, suitable for localized cancer.

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Radical Prostatectomy

Surgical removal of the entire prostate gland and lymph nodes, either through open surgery or a minimally invasive keyhole approach.

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External Beam Radiotherapy (EBRT)

Using high-energy X-rays directed from outside the body to target the tumor.

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Brachytherapy

A type of radiotherapy where radioactive seeds are implanted directly into the prostate gland.

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Radical Treatments for Prostate Cancer

Options include surgery (Radical Prostatectomy), radiation therapy (External Beam Radiotherapy or Brachytherapy), and hormone therapy.

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Prostate Cancer Treatment

A variety of treatments for prostate cancer, including radiation therapy, hormone therapy, chemotherapy, and bisphosphonates. Treatment depends on the stage of the cancer and the individual's health.

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Radiation Therapy for Prostate Cancer

Using either permanent radioactive seeds or temporary radioactive sources to directly target the prostate gland.

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Hormone Therapy for Prostate Cancer

Treatment that lowers testosterone levels, such as surgery or medications, to slow cancer growth.

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Chemotherapy for Prostate Cancer

Using powerful drugs to kill cancer cells, typically for advanced cases.

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Bisphosphonates for Prostate Cancer

Medicines that prevent bone breakdown, used for bone pain and weakening due to cancer.

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Androgen Deprivation Therapy

A hormone therapy for prostate cancer that lowers testosterone levels, using medications or surgery.

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Adverse Effects of Androgen Deprivation

Side effects from lowering testosterone, including changes in body shape, weight gain, fatigue, hot flashes, and decreased libido.

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Erectile Dysfunction (ED)

The persistent inability to achieve or maintain an erection sufficient for satisfactory sexual performance.

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ED: Impact on Life

Erectile dysfunction can have a substantial impact on quality of life, affecting self-esteem, intimacy, and relationships.

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Prostate Cancer Follow Up

Regular check-ups and monitoring for disease progression, including PSA levels and bone pain.

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Phosphodiesterase-5 inhibitors

Medications used for erectile dysfunction. They can cause side effects like hives, chest pain, and a painful erection that lasts for hours.

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Alpha blockers

Medications used to treat high blood pressure and enlarged prostate. They can cause side effects like dizziness, decreased sexual drive, and problems with ejaculation.

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Male Pattern Baldness (MPB)

A common type of hair loss in men, characterized by a receding hairline and thinning on the crown. It's caused by the conversion of testosterone into dihydrotestosterone (DHT).

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What causes MPB?

Male hormones are involved. Cells in the scalp convert testosterone into dihydrotestosterone (DHT), which shrinks hair follicles and reduces hair growth.

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Diagnosis of MPB

Diagnosis is based on history (family history, age of onset) and physical examination. It's important to rule out other causes of hair loss.

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Benign Prostatic Hyperplasia (BPH)

A condition where the prostate gland enlarges, pressing on the urethra and causing urinary problems. It's usually a non-cancerous growth.

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BPH Symptoms

Hesitancy during urination, interrupted or decreased urine flow, frequent urination at night, incomplete emptying of the bladder, and urinary retention.

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BPH Risk Factors

Age over 40, family history of BPH, obesity, heart and circulatory disease, type 2 diabetes, lack of physical exercise, and erectile dysfunction.

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BPH Lifestyle Changes

Reduce liquid intake, avoid caffeine and alcohol, be mindful of certain medications (decongestants, antihistamines, antidepressants, diuretics), exercise pelvic floor muscles, and treat constipation.

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Alpha Blockers for BPH

Doxazosin, Tamsulosin, and Alfuzosin relax the muscles in the prostate and bladder, making urination easier.

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Phosphodiesterase-5 Inhibitors for BPH

Tadalafil, Sildenafil, and Vardenafil help relax the muscles of the penis, improving blood flow and facilitating urination.

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5-Alpha Reductase Inhibitors for BPH

Finasteride and Dutasteride shrink the prostate by blocking a hormone that promotes prostate growth.

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Combination Therapy for BPH

Combining alpha blockers and antimuscarinics can improve symptoms and urinary flow for those with overactive bladder.

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Overactive Bladder

A condition where bladder muscles contract uncontrollably, causing frequent urination, urgency, and leaks.

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Antimuscarinics for Overactive Bladder

These medications relax the bladder muscles to reduce spasms and improve bladder control.

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Study Notes

Male Health Overview

  • This is a lecture covering various aspects of male health concerns, including prostate cancer, erectile dysfunction, benign prostatic hyperplasia, and male pattern baldness.

Prostate Cancer

  • What is the prostate? A gland, walnut-sized, growing larger with age; located under the bladder, surrounding the urethra (urine tube). Its function aids in semen production.
  • Prevalence: Approximately 1 in 8 men in the UK will develop prostate cancer at some point in their lives.
  • Risk factors: Age (over 50, increasing risk with age), family history (father or brother with diagnosis at higher risk), certain ethnicities (Black men at higher risk, particularly over 45), and family history of breast cancer in mother or sister.
  • Symptoms: Increased urgency to pee, straining while urinating, feeling like the bladder hasn't emptied, blood in the urine. These symptoms appear when the prostate grows large enough to affect the urethra.
  • Other prostate issues: Enlarged prostate (common in older men) and prostatitis (inflammation of the prostate, affects all ages). Both are non-cancerous.
  • Testing: PSA blood test (Prostate-Specific Antigen), a common first step, is not perfect. Elevated PSA levels can signal other conditions like infection. Digital rectal exam (DRE), and biopsy are other procedures, based on more tests and PSA results.
  • Treatment: includes various options and procedures (radical prostatectomy, external beam radiotherapy, brachytherapy, etc.). Often, the best treatment depends on the extent of the cancer. Watchful waiting/active surveillance are other treatment options for localized cases.
  • Hormone therapy: Used to lower testosterone levels.
  • Chemotherapy: An option for men with relapsed metastatic disease (disease spreading).

Erectile Dysfunction

  • Definition: Persistent inability to achieve and maintain a sufficient erection for satisfactory sexual performance.
  • Causes: Organic factors (vascular issues like atherosclerosis, blood vessel damage, diabetes), psychological factors (stress, anxiety, depression), certain medical conditions, and medications. Certain medications like diuretics, antihypertensives, antipsychotics, antidepressants, corticosteroids, H2-antagonists & anticonvulsants, can cause ED.
  • Important Note: Some common health conditions like diabetes can severely impact erectile function.
  • Treatment: Lifestyle changes (weight loss, smoking cessation, regular exercise), medications (PDE5 inhibitors, e.g., Viagra, Cialis). Lifestyle changes, stress management, and counseling are often effective supplemental therapies.
  • Risk factors: Several conditions and factors contribute to ED, including Peyronie's disease, depression, issues with sexual relationships, and smoking/related issues.
  • Complications: The underlying causes of erectile dysfunction should be treated as appropriate.

Benign Prostatic Hyperplasia (BPH)

  • Definition: Non-cancerous enlargement of the prostate gland.
  • Causes: Increase in stromal and epithelial cells in the prostate, resulting in prostate size increase. Compressing the urethra.
  • Symptoms: Hesitancy starting urination, interrupted/reduced urinary flow, nocturia (frequent urination at night), incomplete bladder emptying, and urinary retention, and in some cases.
  • Risk factors: Age over 40, family history of BPH, obesity, heart disease, type 2 diabetes.
  • Tests and Diagnosis: Based on symptoms and physical examination, and medical history. PSA tests can be helpful in distinguishing between BPH and prostate cancer.
  • Treatment: lifestyle changes (reducing liquid intake particularly before sleeping/leaving the home, avoiding/reducing alcoholic & caffeinated beverages, exercising pelvic floor muscles), medication, minimal invasive surgical procedures.

Male Pattern Baldness (MPB)

  • Definition: A common type of hair loss in men, usually starting at the temples and the crown of the head.
  • Causes: Genetic predisposition, dihydrotestosterone (DHT), where the hormone DHT creates more sensitivity toward the hair follicles.
  • Stages: MPB progresses through different stages of hair thinning, including the reduction of overall hair density.
  • Diagnosis: Based on a person's medical history and physical examination (looking at hair loss pattern).
  • Treatment: Many treatments exist, from hair transplants to topical medications. Depending on the severity of the condition.
  • Important Considerations: While hair loss may be a significant concern, MPB is typically not associated with other serious health conditions.

Other Important Notes

  • The document emphasizes the importance of professional medical consultation for any health issues. These notes are not intended as medical advice
  • There are various other potential complications associated with these issues.

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Test your knowledge on prostate health, including the prostate gland's functions, common symptoms of prostate cancer, and diagnostic methods. This quiz covers essential information relevant to understanding prostate conditions and their implications.

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