Questions and Answers
What is the generic name of the drug?
Propofol
What is the trade name of Propofol?
Diprivan
What class of drug is Propofol?
Sedative Hypnotic
What is the primary action of Propofol?
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What are the indications for using Propofol?
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What routes can Propofol be administered?
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What are some contraindications for using Propofol?
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What are potential adverse effects of Propofol?
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What is a special consideration when administering Propofol?
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What is the typical dose range for Propofol?
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Study Notes
Propofol Overview
- Generic Name: Propofol
- Trade Name: Diprivan
Classification
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Class: Sedative Hypnotic
- Functions primarily to induce sleep in patients.
Mechanism of Action
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Action: Decreases likelihood of nerve cell activation.
- Alters neurotransmission at synapses, reducing the chance of messages being relayed between nerve cells.
Clinical Uses
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Indications:
- Primarily used for anesthesia induction and maintenance.
- Provides sedation for patients on mechanical ventilation.
Administration Routes
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Route:
- Administered intravenously (IV) or intraosseously (IO).
Contraindications
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Contraindications:
- Not suitable for patients with hypovolemia.
- Avoid in individuals allergic to soybean oil, peanuts, or eggs.
- Use is contraindicated during pregnancy and breastfeeding.
Adverse Effects
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Adverse Effects:
- Can lead to serious complications, including seizures, apnea, and various cardiac dysrhythmias.
- Potential outcomes include asystole, hypotension, hypertension, nausea, vomiting, involuntary muscle movements, and acute renal failure.
Administration Considerations
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Special Considerations:
- Requires regular dosing to maintain effective sedation levels.
- Sedation effects diminish rapidly after cessation.
- May cause localized pain upon injection.
Dosing Information
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Dose:
- Typical dosage ranges from 1.5 to 3 mg/kg depending on patient needs.
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Test your knowledge on Propofol with these flashcards. Each card covers essential information such as its generic name, trade name, class, and action in the body. Perfect for students and healthcare professionals looking to enhance their understanding of this sedative hypnotic drug.