Propofol Drug Card Flashcards

Propofol Overview

• Generic Name: Propofol
• Trade Name: Diprivan

Classification

• Class: Sedative Hypnotic
  • Functions primarily to induce sleep in patients.

Mechanism of Action

• Action: Decreases likelihood of nerve cell activation.
  • Alters neurotransmission at synapses, reducing the chance of messages being relayed between nerve cells.

Clinical Uses

• Indications:
  • Primarily used for anesthesia induction and maintenance.
  • Provides sedation for patients on mechanical ventilation.

Administration Routes

• Route:
  • Administered intravenously (IV) or intraosseously (IO).

Contraindications

• Contraindications:
  • Not suitable for patients with hypovolemia.
  • Avoid in individuals allergic to soybean oil, peanuts, or eggs.
  • Use is contraindicated during pregnancy and breastfeeding.

Adverse Effects

• Adverse Effects:
  • Can lead to serious complications, including seizures, apnea, and various cardiac dysrhythmias.
  • Potential outcomes include asystole, hypotension, hypertension, nausea, vomiting, involuntary muscle movements, and acute renal failure.

Administration Considerations

• Special Considerations:
  • Requires regular dosing to maintain effective sedation levels.
  • Sedation effects diminish rapidly after cessation.
  • May cause localized pain upon injection.

Dosing Information

• Dose:
  • Typical dosage ranges from 1.5 to 3 mg/kg depending on patient needs.