Pharmacology of Propofol
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Pharmacology of Propofol

Created by
@VersatileCopernicium

Questions and Answers

What is the therapeutic class of Propofol?

  • Sedative
  • General anesthetic (correct)
  • Analgesic
  • Antiemetic
  • What is the pharmacologic class of Propofol?

    N-methyl-D-aspartate (NMDA) receptor agonist

    What are some actions and uses of Propofol?

    Induction and maintenance of general anesthesia.

    What should be considered when administering Propofol?

    <p>Only trained personnel should administer Propofol.</p> Signup and view all the answers

    Which are common adverse effects of Propofol?

    <p>Apnea</p> Signup and view all the answers

    What is Propofol infusion syndrome (PIF)?

    <p>A collection of metabolic abnormalities and organ system failures.</p> Signup and view all the answers

    Propofol is contraindicated in patients with hypersensitivity to its components.

    <p>True</p> Signup and view all the answers

    Propofol is pregnancy category ______.

    <p>B</p> Signup and view all the answers

    Study Notes

    Therapeutic Class

    • Classified as a general anesthetic.

    Pharmacologic Class

    • Acts as an N-methyl-D-aspartate (NMDA) receptor agonist.

    Actions and Uses

    • Most widely used intravenous anesthetic due to effectiveness and safety.
    • Indicated for both induction and maintenance of general anesthesia.
    • Features rapid onset of action, suitable for conscious sedation.
    • Allows for quick emergence from anesthesia with minimal adverse effects.
    • Exhibits antiemetic properties, helping to prevent nausea and vomiting.

    Administration Alerts

    • Faster onset and deeper sedation compared to standard doses of benzodiazepines.
    • Should only be administered by trained professionals in general anesthesia.
    • Classified as pregnancy category B, indicating a low risk to pregnant individuals.

    Adverse Effects

    • Common side effects include pain at the injection site, apnea, respiratory depression, and hypotension.
    • Risk of propofol infusion syndrome (PIF), which includes severe metabolic acidosis, hyperkalemia, lipidemia, rhabdomyolysis, hepatomegaly, and potential cardiac failure.

    Contraindications

    • Contraindicated for individuals with known hypersensitivity to propofol or its emulsion, which contains soybean and egg products.
    • Not recommended for obstetric use, including cesarean deliveries or nursing mothers.
    • Caution required for patients with existing cardiac or respiratory impairments.

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    Description

    This quiz covers the essential aspects of Propofol, including its therapeutic and pharmacologic classes as well as its actions and uses. Test your knowledge on this widely used IV anesthetic and its role in general anesthesia.

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