Questions and Answers
What is the name of the drug?
Promethacon
What is the official or generic name of Promethacon?
promethazine
What are the pharmacological and therapeutic classifications of Promethazine?
Pharmacological: phenothiazines; Therapeutic: antiemetic, antihistamine, sedative, hypnotic
What is the chief action of Promethazine?
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What are the primary uses of Promethazine?
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What are the usual dosage methods for Promethazine?
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What are common toxic manifestations of Promethazine?
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What is the life-threatening condition associated with Promethazine?
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What is the pregnancy classification of Promethazine?
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What patient teaching should be provided regarding Promethazine?
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Study Notes
Promethazine Overview
- Generic Name: Promethazine
- Pharmacological Class: Phenothiazines
- Therapeutic Class: Antiemetic, antihistamine, sedative, hypnotic
Mechanism of Action
- Blocks histamine effects, providing relief in allergic reactions
- Inhibits the chemoreceptor trigger zone in the medulla, reducing nausea and vomiting
- Alters dopamine effects in the central nervous system (CNS)
- Exhibits significant anticholinergic activity
- Causes CNS depression by decreasing stimulation of the reticular system
Therapeutic Effects
- Alleviates symptoms from excess histamine and allergic reactions
- Diminishes nausea and vomiting
- Induces sedation
Indications for Use
- Treats various allergic conditions and motion sickness
- Provides preoperative sedation
- Prevents and treats nausea and vomiting
- Serves as an adjunct in anesthesia and analgesia
Routes of Administration
- Administered orally (PO), intramuscularly (IM), intravenously (IV), or rectally
Toxicity and Side Effects
- Common Side Effects: Confusion, disorientation, sedation
- Life-Threatening Risks: Neuroleptic malignant syndrome
Safety Classifications
- Pregnancy Category: C
- High Alert Medication: High risk for significant patient harm if misused
Patient Education
- May cause drowsiness; exercise caution
- Photosensitivity may occur
- Advise patients to rise slowly from sitting or standing positions
- Recommend frequent mouth rinsing and maintaining good oral hygiene
- Suggest using sugarless gum or candy
- Avoid alcohol consumption
- Notify healthcare team of sore throat, jaundice, fever, or uncontrolled movements
Nursing Considerations
- Ongoing patient assessment required
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Description
This quiz explores the pharmacological properties of Promethazine, including its mechanisms of action, therapeutic effects, and clinical indications. You will learn about its uses in treating allergic reactions and nausea, as well as its role in sedation. Understand how this medication works in the body through various routes of administration.
