Phenergan Flashcards
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Questions and Answers

What is the generic name for Phenergan?

  • Antihistamine
  • Histanil
  • Anti-Emetic
  • Promethazine (correct)

What are the trade names for Promethazine?

  • Phenergan
  • Histanil (correct)
  • Zofran
  • Promethacon (correct)

Which classifications apply to Phenergan?

  • Anti-Emetic (correct)
  • Analgesic
  • Sedative
  • Antihistamine (correct)

What is the action of Phenergan?

<p>Blocks effects of histamine, blocks vomit reflex in medulla</p> Signup and view all the answers

The drug should be given in concentrations no greater than _____ mg/mL.

<p>25</p> Signup and view all the answers

What are the indications for using Phenergan?

<p>Treatment of allergic reactions and motion sickness</p> Signup and view all the answers

Which of the following are adverse reactions of Phenergan?

<p>Confusion (A), Neuroleptic malignant syndrome (B), Sedation (D)</p> Signup and view all the answers

What are the contraindications for using Phenergan?

<p>Coma, angle-closure glaucoma, alcohol, bisulfates</p> Signup and view all the answers

Which substances may interact with Phenergan?

<p>SNC depressants (A), Antihistamines (C), Alcohol (D)</p> Signup and view all the answers

What nursing implications should be considered when administering Phenergan?

<p>Assess IV site, monitor BP, P, RR, assess LOC, assess emesis symptoms, monitor CBC</p> Signup and view all the answers

Study Notes

Phenergan Overview

  • Generic name: Promethazine
  • Trade names include Histanil and Promethacon

Classification

  • Functions as an anti-emetic and antihistamine

Mechanism of Action

  • Blocks histamine effects
  • Inhibits the vomiting reflex located in the medulla

Administration Guidelines

  • Maximum concentration: 25 mg/mL
  • Administer no faster than 25 mg/minute
  • Can be diluted in 10 to 20 mL of normal saline for IV infusion
  • Preferred administration site: large-bore veins, ideally via central venous access
  • IV administration time frame: 10 to 15 minutes
  • Injection should occur through a port that is farthest from the patient's vein to reduce complications

Indications for Use

  • Effective for treating allergic reactions
  • Used to alleviate motion sickness

Potential Adverse Reactions

  • Neuroleptic malignant syndrome, confusion, and disorientation
  • Sedation可能性
  • Highly caustic; can damage blood vessel intima and surrounding tissues
  • Immediate cessation of injection is required if burning sensation occurs, to assess for possible complications

Contraindications

  • Not suitable for patients in a coma
  • Avoid in individuals with angle-closure glaucoma
  • Contraindicated with alcohol and bisulfites

Drug Interactions

  • Caution with central nervous system (CNS) depressants like alcohol and opioids
  • Interaction with antihistamines

Nursing Considerations

  • Regularly assess IV site integrity
  • Monitor vital signs: blood pressure, pulse, and respiratory rate
  • Evaluate level of consciousness (LOC)
  • Observe for signs of vomiting (emesis)
  • Monitor complete blood count (CBC) for any changes

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Description

Test your knowledge of Phenergan with these flashcards. This quiz covers its generic name, trade names, classification, action, and recommended dosage. Perfect for pharmacy students and healthcare professionals.

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