Principles of MLS Practice 1

History of Medical Laboratory Science

• Intestinal analysis for disease diagnosis dates back to 1550 BC, with references to Ascaris lumbricoides and taenia species in the Ebers Papyrus.
• Arabian physicians identified parasites as the cause of scabies, highlighting the role of parasitic infection in disease.

17th Century Developments

• Antonie van Leeuwenhoek, known as the "Father of Microbiology," made significant observations in microbiology without formal scientific training.
• He was the first to document protozoa, red blood cells, and sperm cells, communicating his findings to the Royal Society of London.

Contribution of Marcello Malpighi

• Marcello Malpighi is recognized as the "Father of Pathology," known for pioneering microscopic anatomy.
• His discoveries revealed previously unseen tissues in the human body, advancing physiology and embryology.

Pathology and Lab Advances in the 19th Century

• Rudolph Virchow earned the title "Father of Modern Pathology," contributing to our understanding of cellular pathology.
• He founded the Archives of Pathology in Berlin and helped establish the scientific basis of modern pathology.

The Role of Aniline in Medicine

• Aniline, a chemical compound, emerged in the mid-19th century Europe, forming the basis for synthetic dyes used in laboratory settings.

Establishment of Clinical Laboratories

• In 1847, the first clinical laboratory was created by William Welch at Johns Hopkins, marking a significant milestone in laboratory medicine.
• 1894 saw Simon Flexner leading the new Pathology department at Johns Hopkins, reinforcing the importance of laboratory work in clinical practice.

Medical Technology Evolution

• Alessandra Gilliani, a 14th-century physician, is credited with early medical technology applications, although she died from an acquired lab infection.
• Importance of laboratory diagnostics was not widely accepted in the U.S. for many years, viewed as scientific luxuries rather than necessities.

This quiz delves into the history, profession, and development of Medical Laboratory Science (MLS) practices. Covering significant historical milestones from 1550 BC to the 17th century, the quiz provides insights into early diagnoses and treatments. Enhance your understanding of the foundations of the MLS profession.