Principles of Immunization in Practice
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Questions and Answers

Which of the following is NOT a reason people might delay or refuse vaccination due to personal beliefs?

  • They believe there is a minimal risk of contracting preventable diseases and treatment is readily available.
  • They believe that a healthy lifestyle and diet are sufficient protection.
  • They prefer not to expose their children to potential side effects from vaccines. (correct)
  • They believe natural immunity is preferable for their children.
  • They may be concerned about the contents of vaccines, such as animal-derived gelatin.
  • Which factor related to access could contribute to vaccine hesitancy?

  • Belief in conspiracy theories about vaccines.
  • Trust in the information provided by healthcare providers.
  • Fear of needles and pain associated with vaccination.
  • Lack of transportation to vaccination clinics. (correct)
  • What type of information source is NOT mentioned as a potential source of vaccine hesitancy?

  • Traditional media news outlets.
  • Social media posts.
  • Information from friends and family.
  • Online communities focused on natural health.
  • Peer-reviewed scientific journals. (correct)
  • Which of the following is NOT a reason mentioned in the text for people desiring more information about vaccines?

    <p>Concerns about long-term side effects of vaccines. (B)</p> Signup and view all the answers

    Based on the text, which aspect of communication is MOST likely to influence vaccine hesitancy in specific populations?

    <p>Cultural beliefs and practices. (D)</p> Signup and view all the answers

    Which of the following is NOT a reason why people might refuse or delay vaccination?

    <p>A positive attitude toward vaccinations. (D)</p> Signup and view all the answers

    What is the main purpose of the "CH & ID SESSIONS" list?

    <p>To provide a schedule of the course's lectures and tutorials. (A)</p> Signup and view all the answers

    Which of the following is NOT mentioned as an assessment component in the course?

    <p>A research paper on a chosen infectious disease. (D)</p> Signup and view all the answers

    Which of the following is NOT a factor considered when introducing a new vaccine?

    <p>Availability of compatible storage equipment (C)</p> Signup and view all the answers

    According to the content, which of these conditions is a contraindication to immunization with a live attenuated vaccine?

    <p>Pregnancy (A)</p> Signup and view all the answers

    Which of the following is NOT mentioned as a feature of an effective vaccine?

    <p>Universality of protection (C)</p> Signup and view all the answers

    Which of the following is NOT a contraindication to immunization, but may require further investigation and consideration?

    <p>Recent administration of another live vaccine (A)</p> Signup and view all the answers

    Which of the following is NOT a characteristic of vaccination that typically results in longer-lasting immunity?

    <p>Boosting doses administered over time (B)</p> Signup and view all the answers

    What distinguishes an infection from an infectious disease?

    <p>Infection involves host invasion, while infectious disease refers to the resulting illness. (A)</p> Signup and view all the answers

    Which characteristic best defines pathogenicity?

    <p>The agent's ability to infect and multiply within the host. (B)</p> Signup and view all the answers

    What term describes a person who carries an infectious agent but does not exhibit any symptoms?

    <p>Asymptomatic case (A)</p> Signup and view all the answers

    In the context of population health, which is a primary goal of communicable disease control?

    <p>To prevent or reduce the transmission of diseases among populations. (A)</p> Signup and view all the answers

    What differentiates the severity of an infectious disease from its pathogenicity?

    <p>Severity relates to the host's reaction, while pathogenicity relates to the agent's potential to cause infection. (B)</p> Signup and view all the answers

    What is the primary purpose of mandatory notification in surveillance?

    <p>To facilitate immediate action during outbreaks (C)</p> Signup and view all the answers

    Which of the following best defines an outbreak?

    <p>Two or more related cases above the background incidence (A)</p> Signup and view all the answers

    Which step is critical before analyzing data during an outbreak investigation?

    <p>Confirming the situation and diagnosis (B)</p> Signup and view all the answers

    What is the importance of creating a case definition in outbreak management?

    <p>To establish clear criteria for identifying related cases (C)</p> Signup and view all the answers

    Which of the following is included in the components of a case definition?

    <p>Reported symptoms and clinical criteria (B)</p> Signup and view all the answers

    What type of surveillance involves the voluntary reporting of cases?

    <p>Sentinel surveillance (D)</p> Signup and view all the answers

    Which strategy is NOT part of the control measures during an outbreak?

    <p>Immediate vaccination of the population (A)</p> Signup and view all the answers

    In the context of case classification, which level indicates the highest certainty?

    <p>Confirmed (A)</p> Signup and view all the answers

    What is the primary portal of exit for the rabies agent?

    <p>Saliva (C)</p> Signup and view all the answers

    Which type of transmission involves touching or biting to directly transfer a disease agent?

    <p>Direct transmission (B)</p> Signup and view all the answers

    What exemplifies an indirect mode of disease transmission?

    <p>Using contaminated surgical instruments (C)</p> Signup and view all the answers

    Which of the following is NOT a common reservoir for diseases?

    <p>Contaminated food (A)</p> Signup and view all the answers

    What is the primary purpose of active surveillance in public health?

    <p>Conducting public health investigations (B)</p> Signup and view all the answers

    Which method is NOT typically classified under methods of disease transmission?

    <p>Vaccination programs (D)</p> Signup and view all the answers

    What does 'One Health' refer to in the context of public health tools?

    <p>Integration of human, animal, and environmental health (D)</p> Signup and view all the answers

    What is the portal of entry for an agent through the skin?

    <p>Bite from an infected animal (A)</p> Signup and view all the answers

    Which of the following statements is true concerning the role of physicians in communicable disease control?

    <p>They play an essential role in mandatory reporting and disease surveillance. (A)</p> Signup and view all the answers

    Which of the following is an example of passive surveillance?

    <p>Mandatory laboratory reporting (D)</p> Signup and view all the answers

    What type of study is most appropriate for determining the attack rate of Shiga-toxin E. coli associated with a specific food item, such as cupcakes, at a party?

    <p>Cohort study (A)</p> Signup and view all the answers

    Which of these is NOT typically considered a step in the process of data analysis for an outbreak investigation?

    <p>Determining the effectiveness of a vaccine (E)</p> Signup and view all the answers

    What is the main purpose of using whole genome sequencing in an outbreak investigation?

    <p>To track the evolution and transmission of the pathogen (D)</p> Signup and view all the answers

    A study that examines the association between eating at a specific restaurant and developing diarrheal illness is most likely what kind of study?

    <p>Case-control study (C)</p> Signup and view all the answers

    Which of the following scenarios would likely result in a propagated epidemic curve?

    <p>Transmission of a disease through repeated contact between infected individuals (C)</p> Signup and view all the answers

    For what purpose are diaries typically used in an outbreak investigation?

    <p>To understand the clinical symptoms of the illness (D)</p> Signup and view all the answers

    What is the primary distinction between the 'probable' and 'confirmed' case definitions in the provided content?

    <p>Laboratory testing results (D)</p> Signup and view all the answers

    Which of the following is NOT a key objective of outbreak management?

    <p>Determining the incubation period of the pathogen (C)</p> Signup and view all the answers

    Which of these analytical approaches can provide valuable insights into the geographic distribution of cases during an outbreak?

    <p>Mapping using Geographic Information Systems (GIS) (D)</p> Signup and view all the answers

    In the provided information, what is the primary source of evidence for the existence of an outbreak?

    <p>Positive PCR results for STEC (C)</p> Signup and view all the answers

    Study Notes

    Principles of Immunization in Practice

    • This presentation covers principles of immunization and vaccination programs.
    • It discusses the uses of immunization, impact of vaccination, precautions, and contraindications.
    • Vaccination programs in practice include sources of information, vaccination programs in Canada, and vaccine hesitancy.

    Role of Immunization

    • The role of immunization is categorized into pre-exposure and post-exposure strategies, focused on the individual and population levels.
    • Pre-exposure strategies aim to prevent illness through measures like vaccination.
    • Post-exposure strategies address situations where individuals have been exposed to a disease.

    Passive Immunization

    • Passive immunization involves administering pre-formed antibodies to boost a recipient's immunity.
    • This approach offers immediate effects and provides short-term immunity.
    • Examples include post-exposure treatment and administering immune globulins.

    Passive Immunizing Agents

    • Standard immune globulins (e.g., measles, Hep A) and specific immune globulins (e.g., Hepatitis B, Rabies, Tetanus, Varicella-Zoster) are passive immunizing agents.
    • Antitoxins (or antisera) such as botulism antitoxin and diphtheria antitoxin are also part of this category.

    Active Immunization

    • Active immunization, also known as vaccination, uses vaccines.
    • Vaccines administer all or part of a micro-organism to trigger an immune response.
    • This method often provides longer-lasting immunity and is usually a pre-exposure measure.

    Impact of Vaccination

    • Vaccination's impact is highly positive given the drastic decrease in occurrences, such as tetanus, over time.

    Effectiveness of Routine Immunization

    • Immunization programs show significant reductions in infectious diseases like tetanus, documented in Canadian statistics from 1957-2008.
    • The cost-effectiveness of various public health interventions is highlighted in a table measuring the cost per life-year saved.

    Precautions & Contraindications

    • Contraindications and precautions for vaccines exist.
    • For live vaccines, significant immunosuppression and pregnancy are contraindications.
    • Recent administration of other live vaccines and vaccine-specific factors should be considered.
    • Anaphylaxis is another major precaution.

    Conditions that are NOT Contraindications to Immunization

    • Premature birth, breastfeeding, and concurrent antibiotic therapy aren't contraindications for inactivated vaccines.
    • Conditions like common illnesses (unless accompanied by fever), allergies, and concerns about past reactions should be explored further or appropriately managed.

    Vaccination Programs

    • Vaccination programs are similar across Canada but may differ in timing or introduction of new vaccines.
    • Population-specific vaccination programs exist.
    • The schedule for these varies regionally.

    Designing Vaccination Programs

    • Effective vaccines need factors such as safety, sustained protection, stability, affordability, and ease of administration.
    • Introduction costs, use/implementation feasibility, and program structure (distribution, records, and surveillance) contribute to cost-effectiveness.
    • The focus of vaccination programs can be general-population based or targeted.

    Surveillance of CD

    • Surveillance of communicable diseases (CD) is an essential aspect of vaccine program effectiveness.
    • Vaccine efficacy (phases 1 to 3) and program effectiveness (phase 4) are part of evaluations and research in vaccine programs.

    Targeted Vaccination

    • Risk groups (age, comorbidities) are prioritized for targeted vaccination.
    • Post-exposure vaccination, situations combining risk exposure and disease, and responding to outbreaks are also targeted.

    Adult Immunizations in NL

    • General population adult vaccination focuses on influenza.
    • Adults over 60 and at-risk populations receive pneumococcal and herpes zoster vaccines.
    • Boosters such as Tdap are given to adults every 10 years and during pregnancy.

    Travel Vaccinations

    • Health Canada provides travel vaccination recommendations.
    • These might not be covered by provincial programs and are region/activity-based.
    • Requirements for entry into other countries (e.g., yellow fever) are important factors for travelers.

    Vaccine Hesitancy

    • Vaccine hesitancy is a topic of discussion around vaccination.
    • Reasons for refusal/delay of vaccination include personal beliefs, safety concerns, and access-related issues.

    Reasons why people refuse/delay vaccination

    • Personal beliefs, the belief that natural immunity is better, or that healthy diets and lifestyles are sufficient reasons for not getting vaccinated.
    • Safety concerns from media, social media, friends, and family.
    • A desire for more information, or difficulty talking to a healthcare provider also contribute.
    • Access limitations like distance, lack of transportation, or child care needs pose hurdles to vaccination for some people.
    • Communication issues like language barriers and cultural preferences are significant factors.

    Outbreak Investigation

    • Confirm diagnosis and existence of an outbreak by defining cases, analyzing data, controlling measures, and communicating effectively.
    • Case definitions, time period, and place of exposure are crucial components of outbreak investigations.

    Epidemiology Triangle

    • The agent, host, and environment interact in the epidemiology triangle.
    • The agent is the causative microbe.
    • The host's susceptibility depends on natural defense mechanisms, genetics, age, health status, and living conditions.
    • The environment is anything affecting the agent and the host.

    Infectious Disease Process/Chain of Infection

    • This process (chain of infection) concerns how infectious diseases spread.
    • It involves agent, reservoir, portals of entry/exit, and mode of transmission.
    • The reservoir is the habitat for the infectious agent.
    • Transmission can be direct (immediate transfer) or indirect (involving fomites, air, water, food, or vectors).

    Tools for Communicable Disease Control

    • Public health tools for communicable disease control include surveillance, vaccination programs, sanitation, one health, case management, and outbreak response.

    Surveillance

    • Surveillance involves ongoing scrutiny of all disease aspects relevant to effective control.
    • Passive surveillance (mandatory physician and laboratory reports), active surveillance (public health investigation), immunization uptake and complications, and environmental monitoring (water, air) are crucial components.

    Control Measures

    • Control measures prevent new primary cases and further transmission of the infection.
    • These include controlling the source, proportionate measures, reassessing effectiveness, hygiene, isolation/quarantine, and prophylactic medication.

    Communication

    • Communication includes informing affected individuals, the healthcare community, relevant authorities, and services involved, and the public.

    When is an outbreak over?

    • An outbreak is considered over when there are no new cases for a significant period (twice the incubation period), the source is contained, and transmission appears interrupted.

    Source Investigation

    • The investigation often involves retrospective cohort studies to identify, trace, and assess the risks linked with the source of an outbreak.

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    Description

    This quiz explores the principles of immunization, focusing on vaccination programs and their impacts. Key topics include pre-exposure and post-exposure strategies, as well as passive immunization methods. Understand the significance of immunization for both individuals and populations.

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