Physiologic Changes in Pregnancy ppt slide 39+
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Questions and Answers

Which of the following skin changes during pregnancy is NOT considered common?

  • Hyperpigmentation
  • Striae gravidarum
  • Melasma
  • Keratosis pilaris (correct)

What hormonal change primarily causes maternal insulin resistance during pregnancy?

  • Higher levels of human placental lactogen (hPL) (correct)
  • Decreased thyroid hormones
  • Elevated cortisol levels
  • Increased estrogen levels

Which factor is NOT a recognized risk for developing gestational diabetes?

  • Family history
  • Obesity
  • Consuming high protein diet (correct)
  • Personal history of metabolic syndrome

What is the primary mechanism by which maternal glucose affects the fetus?

<p>Maternal glucose crosses the placenta by diffusion (A)</p> Signup and view all the answers

Which immune change occurs during pregnancy?

<p>Decreased NK cell numbers by 30% (D)</p> Signup and view all the answers

Which complication is associated with fetal exposure to maternal hyperglycemia?

<p>Neonatal hyperbilirubinemia (D)</p> Signup and view all the answers

What is the primary purpose of a TORCH titer?

<p>To assess maternal antibodies for specific infections (B)</p> Signup and view all the answers

Which of the following is NOT a fetal complication related to maternal diabetes?

<p>Increased lung maturity (D)</p> Signup and view all the answers

What underlying factor contributes to increased maternal insulin resistance during pregnancy?

<p>Increased cortisol due to placental CRH stimulation (A)</p> Signup and view all the answers

Which skin change associated with pregnancy is a direct result of estrogen sensitivity?

<p>Spider angiomata (D)</p> Signup and view all the answers

How does maternal glucose crossing the placenta affect fetal insulin levels?

<p>Higher maternal glucose leads to elevated fetal insulin production. (B)</p> Signup and view all the answers

Which of the following represents a common alteration in immunology during pregnancy?

<p>Decrease in the number of natural killer cells (A)</p> Signup and view all the answers

What is a potential consequence for a fetus resulting from exposure to maternal high glucose levels?

<p>Increased operative delivery rates due to fetal macrosomia (D)</p> Signup and view all the answers

Which condition could be indicated by a high TORCH titer in a pregnant individual?

<p>Syphilis infection (B)</p> Signup and view all the answers

What is a significant outcome of gestational diabetes related to fetal development?

<p>Weight distribution change favoring the fetal abdomen (B)</p> Signup and view all the answers

Which statement about maternal immunology during pregnancy is true?

<p>IgG antibodies can cross the placenta. (D)</p> Signup and view all the answers

Flashcards

Skin Changes in Pregnancy

Pregnancy causes changes in skin, including spider angiomata (estrogen-related), hair growth, stretch marks (striae gravidarum), hyperpigmentation, and melasma. Rashes and acne are also common.

Maternal Insulin Resistance

During pregnancy, hormones like human placental lactogen (hPL) and elevated cortisol lead to reduced maternal responsiveness to insulin.

Gestational Diabetes Risk Factors

Family history, personal history of metabolic syndrome, and obesity increase the risk of gestational diabetes. Some ethnicities have higher prevalence.

Fetal Macrosomia

Excessive fetal growth, particularly in the shoulders and abdomen, frequently observed in pregnancies complicated by maternal diabetes.

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Maternal Glucose Crossing the Placenta

Maternal glucose passes through the placenta to the fetus primarily via diffusion.

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TORCH Titer

A blood test assessing maternal antibodies against infections like toxoplasmosis, syphilis, and certain viruses, to detect potential exposure in pregnancy.

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Immune System Changes in Pregnancy

Pregnancy alters the immune system to accommodate the fetus (an allograft), modulating away from cytotoxic T-cell activity and decreasing NK cells.

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Fetal Glucose Storage

The developing fetus preferentially stores excess glucose as glycogen in the liver, trunk, and shoulders.

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Maternal Insulin Resistance

During pregnancy, hormones like hPL and cortisol reduce the mother's response to insulin.

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Gestational Diabetes Risk

Family history, pre-existing conditions, and obesity increase risk.

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Fetal Macrosomia

Oversized baby due to high maternal glucose.

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Glucose Crossing Placenta

Mom's glucose passes to the baby through diffusion.

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TORCH Titer

Blood test for antibodies against infections like Toxoplasmosis.

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Immune System Changes

Pregnancy alters immunity to accept fetus, decreasing some cell types.

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Fetal Glucose Storage

Baby stores excess sugar as glycogen in key areas.

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Skin Changes

Pregnancy causes skin changes like stretch marks, pigmented spots, and spider veins.

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