PLTW: Medical Interventions - Cancer Review
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Questions and Answers

Which diagnostic imaging technique does NOT expose the patient to ionizing radiation?

  • CT scans
  • Bone scans
  • X-rays
  • MRIs (correct)

What best describes the function of an oncogene in cancer development?

  • Is normally present and active in all cells
  • Is over-expressed in cancer (correct)
  • Repairs errors in DNA
  • Produces proteins that slow cell division

Which cellular characteristic is most indicative of a cancerous cell?

  • A group of cells that exhibit contact inhibition
  • A group of cells that are all similar in size and shape
  • A cell with single small nucleus
  • A cell with a large, multi-lobed nucleus (correct)

DNA microarrays are used to compare the abundance of what molecule between healthy and experimental cells?

<p>mRNA (A)</p> Signup and view all the answers

Smoking is classified as what type of risk factor for cancer?

<p>behavioral (D)</p> Signup and view all the answers

A proto-oncogene is responsible for which of the following cellular functions?

<p>Controlling cell division (A)</p> Signup and view all the answers

What is the primary function of tumor suppressor genes?

<p>Inhibiting cell cycle progression and promoting apoptosis (C)</p> Signup and view all the answers

Which process describes how cancer cells stimulate the formation of new blood vessels to nourish a tumor?

<p>Angiogenesis (A)</p> Signup and view all the answers

Why is melanoma considered a potentially lethal form of skin cancer?

<p>It has the potential to metastasize and spread aggressively if not detected early. (B)</p> Signup and view all the answers

How does ultraviolet (UV) radiation contribute to the development of cancer?

<p>By inducing mutations in DNA, potentially leading to uncontrolled cell growth. (A)</p> Signup and view all the answers

Becky and Susan both carry the BRCA mutation. Given this information alone, what can be definitively concluded about their sisters, Marie and Margo?

<p>It cannot be determined whether Marie or Margo have the BRCA mutation without genetic testing. (A)</p> Signup and view all the answers

Which of the following viruses is generally NOT associated with an increased risk of developing cancer?

<p>H1N1 influenza (B)</p> Signup and view all the answers

What is the most common classification for the majority of cancers, based on their origin?

<p>Sporadic (A)</p> Signup and view all the answers

A woman who has a family history of breast cancer should consult with their doctor about when they should have their first scheduled _____.

<p>Mammogram (B)</p> Signup and view all the answers

A researcher is investigating the effects of a novel chemical compound on cellular DNA. After exposing cells to the compound, they observe an increased frequency of double-strand breaks. Which of the following cellular processes would most likely be activated as a direct response to this damage?

<p>Activation of DNA repair mechanisms (D)</p> Signup and view all the answers

A research study identifies a new gene, which when mutated, significantly increases an individual's susceptibility to developing colon cancer. Further analysis reveals that this gene plays a critical role in DNA mismatch repair. Which of the following mechanisms is most likely compromised by this mutation, leading to increased cancer risk?

<p>The cell's ability to identify and correct errors introduced during DNA replication. (D)</p> Signup and view all the answers

Why do individuals undergoing chemotherapy often experience hair loss?

<p>Chemotherapy targets and destroys rapidly dividing cells, including hair cells. (A)</p> Signup and view all the answers

What does a correlation coefficient of -0.90 between two genes indicate?

<p>The genes exhibit a strong, opposite behavior. (B)</p> Signup and view all the answers

Given a Pearson correlation coefficient of 0.58 between gene 1 and gene 2, how would you best describe their behavior?

<p>The genes behave similarly. (A)</p> Signup and view all the answers

If a scientist observes a strong positive correlation between the expression of Gene A and the severity of a particular disease, which of the following inferences is most reasonable?

<p>Increased expression of Gene A is associated with increased disease severity. (A)</p> Signup and view all the answers

A study finds that a gene has a correlation coefficient of nearly 0 with a particular disease. What does this suggest?

<p>The gene’s expression is likely unrelated to the disease. (B)</p> Signup and view all the answers

What is a key advantage of chemotherapy compared to radiation therapy in cancer treatment?

<p>Chemotherapy can reach cancer cells throughout the body, while radiation therapy is localized. (A)</p> Signup and view all the answers

During a biofeedback session, which physiological change would indicate a positive response to the therapy?

<p>A decrease in heart rate, indicating relaxation. (C)</p> Signup and view all the answers

Which diagnostic imaging technique involves the use of a radioactive tracer to visualize internal structures?

<p>Bone scan. (B)</p> Signup and view all the answers

People who eat lots of red meat tend to develop cancer. What type of risk factor is this?

<p>Behavioral (A)</p> Signup and view all the answers

Skin cancer is far less common in people of African descent. What type of risk factor is this?

<p>Biological (B)</p> Signup and view all the answers

Which type of cancer would be best suited for radiation therapy?

<p>A small brain tumor (D)</p> Signup and view all the answers

A researcher is studying two genes, Gene X and Gene Y, in a cancer cell line. They observe that when Gene X is highly expressed, Gene Y's expression decreases, and vice versa. All of the following correlation coefficients could describe the relationship between Gene X and Gene Y, except:

<p>0.03 (C)</p> Signup and view all the answers

Flashcards

What is an MRI?

A diagnostic imaging technique that does NOT expose patients to ionizing radiation.

What is an oncogene?

A gene that, when over-expressed, can contribute to the development of cancer.

Cancerous cell characteristics

Cells that are large, have multi-lobed nucleus, lack contact inhibition, and vary in size/shape.

What do DNA microarrays compare?

Compares the amount of mRNA present in healthy vs. experimental cells.

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What is a behavioral risk (cancer)?

A risk factor for cancer related to personal habits and lifestyle choices.

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What is an environmental risk (cancer)?

Factors in your surroundings that can increase cancer risk.

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What is a biological risk (cancer)?

A biological risk factor from within your bodies systems.

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What is a genetic risk (cancer)?

A risk factor that is passed through genetics from your parents.

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Melanoma

A potentially lethal form of skin cancer.

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How UV radiation causes cancer

By causing mutations in the DNA.

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Virus NOT linked to increased cancer risk

H1N1 influenza.

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Most cancers are...

Sporadic.

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First mammogram age

Between 40 and 50.

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BRCA genes

Genes that regulate cell division and repair DNA.

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Apoptosis

A process of programmed cell death.

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STRs

Specific repetitive DNA sequences used in forensics.

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Chemotherapy vs. Radiation: Advantage

Chemotherapy reaches cells throughout the body, while radiation is typically localized to a specific area.

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Why does chemo cause hair loss?

Chemotherapy targets rapidly dividing cells, including hair cells, leading to hair loss.

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What does a correlation of -0.90 mean?

A correlation coefficient of -.90 indicates a strong, inverse relationship between two genes.

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Biofeedback: Positive Response

A decrease in heart rate indicates a positive response to biofeedback.

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What does a Pearson coefficient of 0.58 mean?

A Pearson Correlation Coefficient of .58 suggests that gene 1 and gene 2 tend to behave similarly.

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Diagnostic Imaging with Radioactive Tracer

A bone scan uses a radioactive tracer to detect bone abnormalities.

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Red Meat Consumption: Risk Factor Type

Eating lots of red meat is a behavioral risk factor for cancer because it involves a lifestyle choice.

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What does Pearson Correlation Coefficient do?

Pearson Correlation Coefficient measures the strength and direction of a linear relationship between two variables.

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How does radiation relate to hair loss?

When cancer has spread to the hair follicle cells, radiation can kill the hair follicles causing temporary hair loss.

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Skin Cancer & African Descent: Risk Factor

Skin cancer being less common in people of African descent is an example of a biological risk factor.

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Cancer Best Suited for Radiation Therapy

A small, localized brain tumor is best for radiation therapy.

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Chemotherapy & Hair Loss: Why?

Chemotherapy drugs target rapidly dividing cells, including hair follicle cells, causing hair loss.

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Study Notes

  • A private Kahoot quiz called "DOGAN MI Unit 3 Review" contains 20 questions about medical interventions, cancer, and Project Lead The Way (PLTW).

Diagnostic Imaging

  • MRI does not expose the patient to ionizing radiation.

Oncogenes

  • An oncogene is a gene that is over-expressed in cancer.

Cancerous Cells

  • A cell with a large, multi-lobed nucleus can be a characteristic of a cancerous cell.

DNA Microarrays

  • DNA microarrays compare the amount of mRNA present in a healthy cell versus an experimental cell.

Cancer Risk Factors

  • Smoking is a behavioral risk factor for cancer.

Melanoma

  • Melanoma is a potentially lethal form of skin cancer.

Ultraviolet Radiation

  • Ultraviolet radiation can cause cancer by causing mutations in the DNA.

BRCA Mutation

  • If Becky and Susan both have the BRCA mutation and neither Marie nor Margo have the muation

Viruses and Cancer Risk

  • H1N1 influenza is least associated with an increased risk for cancer

Cancer Development

  • The majority of cancers are considered to be sporadic.

Mammograms

  • A healthy female with no family history should get her first mammogram between 40 and 50 years old.

Chemotherapy Advantages

  • Chemotherapy reaches cells throughout the body, but radiation is localized.

Biofeedback

  • When using biofeedback, a decrease in heart rate would indicate a positive response

Radioactive Tracers

  • A bone scan is a diagnostic imaging technique that uses a radioactive tracer.

Red Meat Consumption

  • Eating lots of red meat is a behavioral risk factor for developing cancer.

Skin Cancer and Risk Factors

  • Skin cancer is far less common in people of African descent due to biological risk factors.

Radiation therapy

  • A small brain tumor would be the best type of cancer to treat with radiation therapy

Chemotherapy and Hair Loss

  • Chemotherapy patients often lose their hair because chemo attacks fast-dividing cells, which includes hair cells.

Correlation Coefficient

  • A correlation coefficient of -0.90 means the two genes have a strong, opposite behavior.

Pearson Correlation Coefficient

  • Using the Pearson Correlation Coefficient, gene 1 and gene 2 have a factor of 0.58 means the genes behave similarly.

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Description

Review of medical interventions and cancer from PLTW. Topics covered include diagnostic imaging such as MRI, oncogenes, cancerous cells, DNA microarrays, cancer risk factors, melanoma, ultraviolet radiation, BRCA mutation, and viruses and cancer risk.

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