Platelet Adhesion and Shape Changes Quiz
18 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the final step that stabilizes and cements the platelet plug to prevent dislodgment?

  • Cross-linking of fibrinogen by thrombin
  • Binding of GPIIbIIIa receptors by fibrinogen
  • Contraction of actin and myosin in platelets
  • Activation of Factor XIII (correct)
  • Which phase of platelet function involves platelets binding together through activated GPIIbIIIa receptors by fibrinogen bridges?

  • Secondary Haemostatic Plug formation
  • Primary Haemostatic Plug formation
  • Clot Retraction
  • Platelet Aggregation (correct)
  • Which drug target inhibits COX1 to prevent platelet activation?

  • Thromboxane (TXA2) inhibitors (correct)
  • Purinergic (P2Y12) Inhibitors
  • Glycoprotein IIb/IIIa Antagonists
  • Protease-activated receptor-1 Antagonists
  • In which phase of platelet function do platelets contract using actin, myosin, and ATP?

    <p>Clot Retraction</p> Signup and view all the answers

    What is the role of Glycoprotein IIb/IIIa Antagonists in platelet function?

    <p>Binding to GP IIb/IIIa receptors</p> Signup and view all the answers

    How do activated Factor XIII contribute to platelet plug stabilization?

    <p>Cross-link fibrinogen to stabilize the plug</p> Signup and view all the answers

    What initiates platelet adhesion by binding to collagen and vWF in the exposed subendothelial surface?

    <p>Glycoprotein VI (GP VI)</p> Signup and view all the answers

    Which event triggers platelet shape changes, making them send out filopodia for better adherence?

    <p>Extracellular Ca influx</p> Signup and view all the answers

    What is released by activated platelets, especially from alpha and dense granules, during platelet degranulation?

    <p>Serotonin, ADP, and fibrinogen</p> Signup and view all the answers

    Which substance acts on platelet surface receptors in an autocrine manner during platelet activation?

    <p>Thromboxane A2 (TXA2)</p> Signup and view all the answers

    What role does thrombin play in platelet activation?

    <p>Act on proteinase receptors on platelet surface</p> Signup and view all the answers

    Which receptors' affinity is increased by activators like thrombin and epinephrine during platelet activation?

    <p>GPIIbIIIa receptors</p> Signup and view all the answers

    Which of the following is NOT a component of the platelet cytosol?

    <p>Granular endoplasmic reticulum</p> Signup and view all the answers

    What is the primary function of the microtubules in the platelet hyalomere?

    <p>To maintain the discoid morphology of the platelet</p> Signup and view all the answers

    Which of the following statements about the open canalicular system (OCS) is INCORRECT?

    <p>It facilitates the formation of pseudopodia during platelet activation</p> Signup and view all the answers

    Which of the following glycoprotein molecules are present in the platelet plasmalemma?

    <p>All of the above</p> Signup and view all the answers

    What is the function of the actin and myosin filaments in the platelet hyalomere?

    <p>To serve in platelet movements and retraction during hemostasis</p> Signup and view all the answers

    Which of the following is a component of the platelet cell coat?

    <p>Glycosaminoglycans</p> Signup and view all the answers

    More Like This

    Quiz
    5 questions

    Quiz

    BuoyantPigeon avatar
    BuoyantPigeon
    2CB3 Chapter 7
    24 questions

    2CB3 Chapter 7

    EarnestLake avatar
    EarnestLake
    Emostasi e Tappe dell'Emostasi
    50 questions
    Use Quizgecko on...
    Browser
    Browser