20 Questions
What is the characteristic of the RNA of Picornavirus?
Positive sense single strand RNA
What is the mode of transmission of Picornavirus?
Fecal oral transmission
What is the function of viral proteases in Picornavirus replication?
To cleave the long protein product
Where does the replication of Picornavirus RNA take place?
In the cytoplasm
Which virus is responsible for Aseptic meningitis?
Echovirus
What is the characteristic of lab findings in Aseptic meningitis?
Normal glucose levels and no growth on plate
Which of the following viruses is transmitted through fecal oral transmission?
Hepatitis A
What is the common cold caused by?
Rhinovirus
Where does the host cell RNA polymerase reside?
In the cytoplasm
What is the characteristic of POS Sense RNA Replication?
Uses host transcription factors
What is the significance of the Statue of David in the context of Picornavirus?
It represents the naked viruses
What is the role of the host RNA polymerase in POS Sense RNA Replication?
It is not required for replication
What is the significance of the coin machine in the context of POS Sense RNA Replication?
It represents the replication process
What is the significance of the tickets in the context of Picornavirus replication?
They represent the long protein product that contains viral proteases
What is the characteristic of Hep A virus?
It is transmitted through fecal-oral route
What is the significance of the Aviary in the context of Picornavirus?
It represents the Enterovirus
What is the significance of the bags of food in the context of Aseptic meningitis?
It represents the lab findings
What is the significance of the space helmet in the context of Aseptic meningitis?
It represents the meningitis
What is the characteristic of the Rhinovirus?
It is transmitted through respiratory route
What is the significance of the Sun with a positive sign in the context of Picornavirus?
It represents the POS sense single strand RNA
Study Notes
Picornavirus Family
- Picornaviruses are positive sense single-stranded RNA viruses.
- They replicate in the cytoplasm, using host cell RNA polymerase.
Characteristics
- Fecal-oral transmission is a common route for picornaviruses, except for Rhinovirus.
- Rhinovirus is associated with the common cold and is not transmitted via the fecal-oral route.
Replication
- POS Sense RNA Replication uses host transcription factors and RNA polymerase, as it is the same sense as the host cell.
- Viral RNA is transmitted into a long protein product that contains viral proteases to cleave it.
Types of Picornaviruses
- Enteroviruses (e.g., Polio, Cocksackie) are types of picornaviruses that can cause aseptic meningitis.
- Rhinovirus is a type of picornavirus that causes the common cold.
- Hepatitis A is a type of picornavirus that affects the liver.
Lab Findings and Clinical Presentation
- Aseptic meningitis is characterized by normal glucose levels, no growth on plate cultures, and elevated protein levels.
- Meningitis is often associated with picornaviruses, with enterovirus being the most common cause in children.
Other
- POS sense replication takes place during the day, while NEG sense replication takes place at night.
- RNA viruses are represented by warm red colors, while DNA viruses are represented by cold blue viruses.
- The "Statue of David" symbolizes a naked virus.
Picornavirus Family
- Picornaviruses are positive sense single-stranded RNA viruses.
- They replicate in the cytoplasm, using host cell RNA polymerase.
Characteristics
- Fecal-oral transmission is a common route for picornaviruses, except for Rhinovirus.
- Rhinovirus is associated with the common cold and is not transmitted via the fecal-oral route.
Replication
- POS Sense RNA Replication uses host transcription factors and RNA polymerase, as it is the same sense as the host cell.
- Viral RNA is transmitted into a long protein product that contains viral proteases to cleave it.
Types of Picornaviruses
- Enteroviruses (e.g., Polio, Cocksackie) are types of picornaviruses that can cause aseptic meningitis.
- Rhinovirus is a type of picornavirus that causes the common cold.
- Hepatitis A is a type of picornavirus that affects the liver.
Lab Findings and Clinical Presentation
- Aseptic meningitis is characterized by normal glucose levels, no growth on plate cultures, and elevated protein levels.
- Meningitis is often associated with picornaviruses, with enterovirus being the most common cause in children.
Other
- POS sense replication takes place during the day, while NEG sense replication takes place at night.
- RNA viruses are represented by warm red colors, while DNA viruses are represented by cold blue viruses.
- The "Statue of David" symbolizes a naked virus.
This quiz covers the key features of the Picornavirus family, including their sense of RNA, transmission methods, and replication processes. Learn about the characteristics of Rhinovirus and other viruses in this family.
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