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Questions and Answers
What is the characteristic of the RNA of Picornavirus?
What is the characteristic of the RNA of Picornavirus?
- Positive sense double strand RNA
- Double strand RNA
- Positive sense single strand RNA (correct)
- Negative sense single strand RNA
What is the mode of transmission of Picornavirus?
What is the mode of transmission of Picornavirus?
- Respiratory transmission
- Fecal oral transmission (correct)
- Vector transmission
- Direct contact transmission
What is the function of viral proteases in Picornavirus replication?
What is the function of viral proteases in Picornavirus replication?
- To cleave the long protein product (correct)
- To synthesize viral RNA
- To translate viral RNA into protein
- To transcribe viral RNA into DNA
Where does the replication of Picornavirus RNA take place?
Where does the replication of Picornavirus RNA take place?
Which virus is responsible for Aseptic meningitis?
Which virus is responsible for Aseptic meningitis?
What is the characteristic of lab findings in Aseptic meningitis?
What is the characteristic of lab findings in Aseptic meningitis?
Which of the following viruses is transmitted through fecal oral transmission?
Which of the following viruses is transmitted through fecal oral transmission?
What is the common cold caused by?
What is the common cold caused by?
Where does the host cell RNA polymerase reside?
Where does the host cell RNA polymerase reside?
What is the characteristic of POS Sense RNA Replication?
What is the characteristic of POS Sense RNA Replication?
What is the significance of the Statue of David in the context of Picornavirus?
What is the significance of the Statue of David in the context of Picornavirus?
What is the role of the host RNA polymerase in POS Sense RNA Replication?
What is the role of the host RNA polymerase in POS Sense RNA Replication?
What is the significance of the coin machine in the context of POS Sense RNA Replication?
What is the significance of the coin machine in the context of POS Sense RNA Replication?
What is the significance of the tickets in the context of Picornavirus replication?
What is the significance of the tickets in the context of Picornavirus replication?
What is the characteristic of Hep A virus?
What is the characteristic of Hep A virus?
What is the significance of the Aviary in the context of Picornavirus?
What is the significance of the Aviary in the context of Picornavirus?
What is the significance of the bags of food in the context of Aseptic meningitis?
What is the significance of the bags of food in the context of Aseptic meningitis?
What is the significance of the space helmet in the context of Aseptic meningitis?
What is the significance of the space helmet in the context of Aseptic meningitis?
What is the characteristic of the Rhinovirus?
What is the characteristic of the Rhinovirus?
What is the significance of the Sun with a positive sign in the context of Picornavirus?
What is the significance of the Sun with a positive sign in the context of Picornavirus?
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Study Notes
Picornavirus Family
- Picornaviruses are positive sense single-stranded RNA viruses.
- They replicate in the cytoplasm, using host cell RNA polymerase.
Characteristics
- Fecal-oral transmission is a common route for picornaviruses, except for Rhinovirus.
- Rhinovirus is associated with the common cold and is not transmitted via the fecal-oral route.
Replication
- POS Sense RNA Replication uses host transcription factors and RNA polymerase, as it is the same sense as the host cell.
- Viral RNA is transmitted into a long protein product that contains viral proteases to cleave it.
Types of Picornaviruses
- Enteroviruses (e.g., Polio, Cocksackie) are types of picornaviruses that can cause aseptic meningitis.
- Rhinovirus is a type of picornavirus that causes the common cold.
- Hepatitis A is a type of picornavirus that affects the liver.
Lab Findings and Clinical Presentation
- Aseptic meningitis is characterized by normal glucose levels, no growth on plate cultures, and elevated protein levels.
- Meningitis is often associated with picornaviruses, with enterovirus being the most common cause in children.
Other
- POS sense replication takes place during the day, while NEG sense replication takes place at night.
- RNA viruses are represented by warm red colors, while DNA viruses are represented by cold blue viruses.
- The "Statue of David" symbolizes a naked virus.
Picornavirus Family
- Picornaviruses are positive sense single-stranded RNA viruses.
- They replicate in the cytoplasm, using host cell RNA polymerase.
Characteristics
- Fecal-oral transmission is a common route for picornaviruses, except for Rhinovirus.
- Rhinovirus is associated with the common cold and is not transmitted via the fecal-oral route.
Replication
- POS Sense RNA Replication uses host transcription factors and RNA polymerase, as it is the same sense as the host cell.
- Viral RNA is transmitted into a long protein product that contains viral proteases to cleave it.
Types of Picornaviruses
- Enteroviruses (e.g., Polio, Cocksackie) are types of picornaviruses that can cause aseptic meningitis.
- Rhinovirus is a type of picornavirus that causes the common cold.
- Hepatitis A is a type of picornavirus that affects the liver.
Lab Findings and Clinical Presentation
- Aseptic meningitis is characterized by normal glucose levels, no growth on plate cultures, and elevated protein levels.
- Meningitis is often associated with picornaviruses, with enterovirus being the most common cause in children.
Other
- POS sense replication takes place during the day, while NEG sense replication takes place at night.
- RNA viruses are represented by warm red colors, while DNA viruses are represented by cold blue viruses.
- The "Statue of David" symbolizes a naked virus.
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