Picornavirus Family Characteristics

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Questions and Answers

What is the characteristic of the RNA of Picornavirus?

  • Positive sense double strand RNA
  • Double strand RNA
  • Positive sense single strand RNA (correct)
  • Negative sense single strand RNA

What is the mode of transmission of Picornavirus?

  • Respiratory transmission
  • Fecal oral transmission (correct)
  • Vector transmission
  • Direct contact transmission

What is the function of viral proteases in Picornavirus replication?

  • To cleave the long protein product (correct)
  • To synthesize viral RNA
  • To translate viral RNA into protein
  • To transcribe viral RNA into DNA

Where does the replication of Picornavirus RNA take place?

<p>In the cytoplasm (A)</p> Signup and view all the answers

Which virus is responsible for Aseptic meningitis?

<p>Echovirus (C)</p> Signup and view all the answers

What is the characteristic of lab findings in Aseptic meningitis?

<p>Normal glucose levels and no growth on plate (C)</p> Signup and view all the answers

Which of the following viruses is transmitted through fecal oral transmission?

<p>Hepatitis A (A)</p> Signup and view all the answers

What is the common cold caused by?

<p>Rhinovirus (B)</p> Signup and view all the answers

Where does the host cell RNA polymerase reside?

<p>In the cytoplasm (A)</p> Signup and view all the answers

What is the characteristic of POS Sense RNA Replication?

<p>Uses host transcription factors (B)</p> Signup and view all the answers

What is the significance of the Statue of David in the context of Picornavirus?

<p>It represents the naked viruses (D)</p> Signup and view all the answers

What is the role of the host RNA polymerase in POS Sense RNA Replication?

<p>It is not required for replication (D)</p> Signup and view all the answers

What is the significance of the coin machine in the context of POS Sense RNA Replication?

<p>It represents the replication process (A)</p> Signup and view all the answers

What is the significance of the tickets in the context of Picornavirus replication?

<p>They represent the long protein product that contains viral proteases (B)</p> Signup and view all the answers

What is the characteristic of Hep A virus?

<p>It is transmitted through fecal-oral route (C)</p> Signup and view all the answers

What is the significance of the Aviary in the context of Picornavirus?

<p>It represents the Enterovirus (A)</p> Signup and view all the answers

What is the significance of the bags of food in the context of Aseptic meningitis?

<p>It represents the lab findings (D)</p> Signup and view all the answers

What is the significance of the space helmet in the context of Aseptic meningitis?

<p>It represents the meningitis (D)</p> Signup and view all the answers

What is the characteristic of the Rhinovirus?

<p>It is transmitted through respiratory route (B)</p> Signup and view all the answers

What is the significance of the Sun with a positive sign in the context of Picornavirus?

<p>It represents the POS sense single strand RNA (B)</p> Signup and view all the answers

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Study Notes

Picornavirus Family

  • Picornaviruses are positive sense single-stranded RNA viruses.
  • They replicate in the cytoplasm, using host cell RNA polymerase.

Characteristics

  • Fecal-oral transmission is a common route for picornaviruses, except for Rhinovirus.
  • Rhinovirus is associated with the common cold and is not transmitted via the fecal-oral route.

Replication

  • POS Sense RNA Replication uses host transcription factors and RNA polymerase, as it is the same sense as the host cell.
  • Viral RNA is transmitted into a long protein product that contains viral proteases to cleave it.

Types of Picornaviruses

  • Enteroviruses (e.g., Polio, Cocksackie) are types of picornaviruses that can cause aseptic meningitis.
  • Rhinovirus is a type of picornavirus that causes the common cold.
  • Hepatitis A is a type of picornavirus that affects the liver.

Lab Findings and Clinical Presentation

  • Aseptic meningitis is characterized by normal glucose levels, no growth on plate cultures, and elevated protein levels.
  • Meningitis is often associated with picornaviruses, with enterovirus being the most common cause in children.

Other

  • POS sense replication takes place during the day, while NEG sense replication takes place at night.
  • RNA viruses are represented by warm red colors, while DNA viruses are represented by cold blue viruses.
  • The "Statue of David" symbolizes a naked virus.

Picornavirus Family

  • Picornaviruses are positive sense single-stranded RNA viruses.
  • They replicate in the cytoplasm, using host cell RNA polymerase.

Characteristics

  • Fecal-oral transmission is a common route for picornaviruses, except for Rhinovirus.
  • Rhinovirus is associated with the common cold and is not transmitted via the fecal-oral route.

Replication

  • POS Sense RNA Replication uses host transcription factors and RNA polymerase, as it is the same sense as the host cell.
  • Viral RNA is transmitted into a long protein product that contains viral proteases to cleave it.

Types of Picornaviruses

  • Enteroviruses (e.g., Polio, Cocksackie) are types of picornaviruses that can cause aseptic meningitis.
  • Rhinovirus is a type of picornavirus that causes the common cold.
  • Hepatitis A is a type of picornavirus that affects the liver.

Lab Findings and Clinical Presentation

  • Aseptic meningitis is characterized by normal glucose levels, no growth on plate cultures, and elevated protein levels.
  • Meningitis is often associated with picornaviruses, with enterovirus being the most common cause in children.

Other

  • POS sense replication takes place during the day, while NEG sense replication takes place at night.
  • RNA viruses are represented by warm red colors, while DNA viruses are represented by cold blue viruses.
  • The "Statue of David" symbolizes a naked virus.

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