Physiology of Hunger and Thirst
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Questions and Answers

What region of the brain controls the regulation of hunger?

hypothalamus

Which hormone released by the stomach stimulates appetite?

ghrelin

What is the role of leptin in hunger regulation?

suppresses appetite

What is the function of neuropeptide Y (NPY) in central signaling pathways?

<p>stimulates appetite</p> Signup and view all the answers

What is the role of gastric distension in short-term regulation of hunger?

<p>signals satiety</p> Signup and view all the answers

What region of the brain controls the regulation of thirst?

<p>hypothalamus, specifically the lamina terminalis</p> Signup and view all the answers

What is the function of osmoreceptors in the regulation of thirst?

<p>detect changes in blood osmolality</p> Signup and view all the answers

What is the role of angiotensin II in the regulation of thirst?

<p>stimulates thirst</p> Signup and view all the answers

What is the role of vasopressin (ADH) in central signaling pathways?

<p>stimulates thirst</p> Signup and view all the answers

What is the effect of decreased blood volume on thirst?

<p>stimulates thirst</p> Signup and view all the answers

Study Notes

Hunger

  • Regulation of Hunger:
    • Controlled by the hypothalamus, a region in the diencephalon
    • Involves a complex interplay of hormonal and neural signals
  • Hormonal Regulation:
    • Ghrelin: released by the stomach, stimulates appetite
    • Leptin: released by adipose tissue, suppresses appetite
    • Insulin: released by the pancreas, suppresses appetite
  • Central Signaling Pathways:
    • Neuropeptide Y (NPY): stimulates appetite
    • Agouti-related peptide (AgRP): stimulates appetite
    • α-Melanocyte-stimulating hormone (α-MSH): suppresses appetite
  • Short-term Regulation:
    • Gastric Distension: stretching of the stomach wall signals satiety
    • Cholecystokinin (CCK): released by the duodenum, signals satiety
    • Glucagon-like peptide-1 (GLP-1): released by the ileum, signals satiety

Thirst

  • Regulation of Thirst:
    • Controlled by the hypothalamus, specifically the lamina terminalis
    • Involves a complex interplay of hormonal and neural signals
  • Osmoreceptors:
    • Osmoreceptors in the hypothalamus: detect changes in blood osmolality
    • Baroreceptors in the aortic arch and carotid sinus: detect changes in blood volume
  • Hormonal Regulation:
    • Angiotensin II: stimulates thirst
    • Atrial natriuretic peptide (ANP): suppresses thirst
  • Central Signaling Pathways:
    • Dopamine: involved in the regulation of thirst
    • ** Vasopressin (ADH)**: released by the hypothalamus, stimulates thirst
  • Short-term Regulation:
    • Dryness of the mucous membranes: stimulates thirst
    • Decreased blood volume: stimulates thirst

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Test your knowledge of the physiological mechanisms that regulate hunger and thirst, including hormonal and neural signals, central signaling pathways, and short-term regulation.

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