Physiology of CNS Sensory Receptors
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Questions and Answers

Most sensory receptors are stimulated by:

  • Multiple stimuli with high thresholds
  • One specific stimulus only
  • Different types of stimuli (correct)
  • Only high energy stimuli
  • What happens when a specific stimulus produces a receptor potential?

  • Enhances K+ efflux from receptors
  • Inhibits Na + influx into receptors
  • Enhances Na + influx into receptors (correct)
  • Inhibits K+ efflux from receptors
  • When initiated by an adequate stimulus, receptor potential can:

  • Undergo spatial summation
  • Always develop at full magnitude
  • Undergo temporal summation
  • Directly initiate an action potential (correct)
  • When exposed to effective steady stimuli, sensory receptors will:

    <p>Soar in impulse rate before declining</p> Signup and view all the answers

    Which of the following is not a slowly adapting receptor?

    <p>Meissner corpuscles</p> Signup and view all the answers

    Rapidly adapting receptors are especially involved in:

    <p>Only 'A' and 'C' are correct</p> Signup and view all the answers

    Concerning the adaptation of receptors, which statement is true?

    <p>It is a decline in responsiveness despite constant stimulation</p> Signup and view all the answers

    The phenomenon of adaptation is most pronounced in which receptors?

    <p>Pacinian corpuscles</p> Signup and view all the answers

    What characteristic of a generator potential is NOT true?

    <p>It can always be blocked by local anesthetic drugs.</p> Signup and view all the answers

    Which type of receptors continue to discharge impulses as long as a stimulus is applied?

    <p>Tonic receptors.</p> Signup and view all the answers

    Which of the following structures does NOT contain proprioceptors?

    <p>Viscera.</p> Signup and view all the answers

    How is the strength of a stimulus perceived?

    <p>By the frequency of neural impulses.</p> Signup and view all the answers

    What determines the perception of a certain modality of sensation?

    <p>The specific receptor and nerve fiber carrying impulses.</p> Signup and view all the answers

    What is the role of connections between receptors and sensory areas in the cortex?

    <p>They influence the perception of modality.</p> Signup and view all the answers

    What does research indicate about food cue activation in binge eating disorder (BN) patients?

    <p>They show greater activation in the lateral prefrontal cortex.</p> Signup and view all the answers

    How is cerebellar atrophy related to the duration of anorexia nervosa (AN)?

    <p>It contributes to the maintenance of low body weight.</p> Signup and view all the answers

    What happens to the receptor potential as stimulus intensity increases?

    <p>It increases the magnitude of receptor potential.</p> Signup and view all the answers

    What was observed in anorexia nervosa patients who did not reach the weight threshold at discharge?

    <p>They had a smaller volume in the right cerebellar crus I at the time of admission.</p> Signup and view all the answers

    Which characteristic is true for slowly adapting receptors?

    <p>They include the Pacinian corpuscles.</p> Signup and view all the answers

    In the context of eating disorders, what change in intrinsic connectivity was observed compared to healthy subjects?

    <p>Lesser connectivity with the insulae and vermis.</p> Signup and view all the answers

    What is the primary hypothesis proposed regarding the role of the cerebellum in schizophrenia?

    <p>Cognitive dysmetria due to a specific circuitry dysfunction is fundamental.</p> Signup and view all the answers

    Which observation is NOT commonly associated with cerebellar impairment in schizophrenia?

    <p>Enhanced memory retention.</p> Signup and view all the answers

    What structural brain change has been consistently observed in patients with schizophrenia?

    <p>Reduced cerebellar volumes, including diminished cerebellar vermis volume</p> Signup and view all the answers

    How have changes in cerebellar volume been linked to schizophrenia?

    <p>They are associated with neural and behavioral abnormalities occurring in the perinatal period and other factors.</p> Signup and view all the answers

    What does functional imaging reveal about blood flow in the cerebellum of schizophrenia patients during cognitive tasks?

    <p>Diminished blood flow to the cerebellar cortex and vermis</p> Signup and view all the answers

    What role does the cerebellum play in anxiety disorders according to recent studies?

    <p>It is connected to fear and anxiety-related areas and is involved in the neural circuitry of these disorders.</p> Signup and view all the answers

    In patients with specific phobias, what was observed in relation to cerebellar activation?

    <p>Cerebellar activation correlated with the level of anxiety induced by viewing feared stimuli.</p> Signup and view all the answers

    How did successful cognitive-behavioral therapy (CBT) affect cerebellar activity in patients with panic disorder?

    <p>It diminished enhanced cerebellar activity observed in baseline conditions.</p> Signup and view all the answers

    Which of the following descriptions accurately reflects impaired coordination in patients with schizophrenia?

    <p>Abnormal posture and proprioception</p> Signup and view all the answers

    What has been suggested regarding the cerebellum's function in relation to anxiety disorders?

    <p>It helps to mediate emotional responses linked to anxiety.</p> Signup and view all the answers

    Which of the following can significantly raise intracranial pressure (ICP)?

    <p>Low glucose levels in CSF</p> Signup and view all the answers

    What is the purpose of the rapid venous drainage from circumventricular organs?

    <p>Facilitating rapid delivery of oxygen and nutrients</p> Signup and view all the answers

    What structures allow cerebrospinal fluid (CSF) to exit the ventricular system into the subarachnoid space?

    <p>Foramina of Luschka and foramen of Magendie</p> Signup and view all the answers

    What type of emotional disturbance is associated with lesions in the 'limbic cerebellum'?

    <p>Flattening of affect or disinhibition</p> Signup and view all the answers

    How do arachnoid granulations function in the reabsorption of CSF?

    <p>They act as one-way valves</p> Signup and view all the answers

    What drives the movement of CSF into the dural venous sinuses?

    <p>The pressure gradient between CSF and venous blood</p> Signup and view all the answers

    Which cognitive function is specifically affected by disruptions in connectivity between the posterior cerebellar lobe and cerebral association areas?

    <p>Multitasking and planning</p> Signup and view all the answers

    What condition can arise from disruptions in CSF reabsorption?

    <p>Hydrocephalus</p> Signup and view all the answers

    What is a common manifestation of the language and speech deficits in CCAS?

    <p>Agrammatism</p> Signup and view all the answers

    The symptoms of CCAS are attributed to disruptions in pathways connecting the cerebellum with what areas?

    <p>Limbic circuitry and various cortical areas</p> Signup and view all the answers

    What role does CSF analysis play in neurology?

    <p>It helps diagnose various conditions</p> Signup and view all the answers

    What happens to arachnoid villi when cerebrospinal fluid pressure increases?

    <p>They disengage from the dural sinuses</p> Signup and view all the answers

    What do recent findings suggest about cerebellar grey matter in Alzheimer's disease?

    <p>It shows significant volumetric reductions in various regions.</p> Signup and view all the answers

    In which specific regions of the cerebellum has significant atrophy been identified in Alzheimer's patients?

    <p>Right crus I and II of lobule VIIa, and lobule VI</p> Signup and view all the answers

    How do amyloid-b deposits in the cerebellum differ between early-onset and late-onset Alzheimer's disease?

    <p>They are located predominantly in the molecular layer of the cerebellar cortex in early-onset AD.</p> Signup and view all the answers

    What is the relationship between cerebellar atrophy and cognitive performance in Alzheimer's disease?

    <p>Poor scoring on the MMSE is associated with smaller volume of the superior posterior lobe.</p> Signup and view all the answers

    Signup and view all the answers

    Study Notes

    Physiology of CNS Sensory Receptors

    • Sensory receptors are stimulated by different types of stimuli
    • Some receptors are stimulated by only one specific stimulus
    • Sensory receptors have a high threshold for specific stimuli
    • A specific stimulus produces a receptor potential by enhancing the influx of Na+ into receptors.
    • Receptor potential is initiated by adequate stimulus, which may not always be fully developed.
    • Sensory receptors stimulated by a steady stimulus can continuously discharge impulses, stop discharging after a brief time, or produce an initial high rate then decline.
    • Receptors differ in their response patterns. Some continuously discharge while others don't react at all to the stimulus.
    • Slowly adapting receptors include Golgi tendon organs, warmth receptors, and free nerve endings (excluding Meissner corpuscles)
    • Rapidly adapting receptors are involved in initiating rapid reflex responses and detecting joint movements.

    Sensory Receptors: Structure and Function

    • Sensory receptors have varied structures across the body.
    • They may not all have the same cellular structure
    • Not all sensory receptors are free nerve endings
    • Receptors adhere to the law of specific nerve energies

    Receptor Adaptation

    • Receptor adaptation is the decline in firing rate despite constant stimulation.
    • Receptor adaptation is due to changes in receptors, making them less responsive to stimuli, instead of receptor fatigue.
    • Adaptation doesn't occur in all receptors to the same degree.
    • Receptor adaptation is not accompanied by a change in receptor potential.

    Adaptation of Sensory Receptors

    • Sensory receptor adaptation is the decline in firing rate despite consistent stimulation
    • Receptor fatigue is not typically the cause of adaptation.
    • Adaptations can result from changes in receptor structure and function.
    • Adaptation processes are unique for each type of sensory receptor.

    Physiology of CNS: Specific Tracts

    • The lateral spinothalamic tract carries conscious information about pain and temperature.
    • Anterior spinothalamic tract carries conscious information related to pain and temperature.
    • The lateral spinothalamic tract's destination is the postcentral gyrus (primary somatosensory cortex).
    • If the lateral spinothalamic tract is damaged, complete loss of pain and temperature sensation below the injury level occurs bilaterally.
    • The Anterior spinothalamic tract is involved in carrying conscious information related to crude and light touch.
    • The destinations of the anterior spinothalamic tract are postcentral gyrus, primary somatosensory cortex.
    • Damage to the anterior spinothalamic tract results in contralateral loss of crude and light touch below the injury level.

    Cerebrospinal Fluid (CSF)

    • Ependymal cells produce cerebrospinal fluid (CSF).
    • Choroid plexus are the main structures that produce CSF
    • CSF plays a vital role in maintaining the integrity of the blood-brain barrier, acting as a buoyancy aid, and facilitating rapid delivery of oxygen and nutrients while cushioning against injuries.
    • CSF is produced in the choroid plexuses
    • CSF is reabsorbed through arachnoid granulations into the dural sinuses
    • Disruptions in CSF reabsorption can lead to conditions like hydrocephalus.

    CSF Analysis and Function

    • CSF analysis can diagnose various neurological conditions.
    • CSF provides vital information for diagnostic purposes.
    • Various conditions can be identified based on analysis of cerebrospinal fluid samples.
    • Mechanisms or conditions can affect the CSF that may cause specific impairments.

    Cerebellar Function and Dysfunction

    • The cerebellum regulates motor coordination and balance.
    • Cerebellar function includes cognitive processes, such as higher-order networks, and sensory perception.
    • Cerebellar function is implicated in specific types of dementia.
    • Cerebellar impairment is associated with motor coordination deficits, cognitive deficits (like memory recall and visual–spatial skills), emotional dysregulation, language comprehension problems, speech and language impairments, and issues with visual-spatial tasks

    Neurological Conditions and Symptoms

    • Patients with cerebellar dysfunction often exhibit cognitive and emotional issues.
    • Cerebellar cognitive and affective syndrome is a neurological condition with cognitive problems, emotional issues, and language-related impairments.
    • Patients may experience impairments or abnormalities in their emotional responses
    • Specific symptoms and conditions are often associated with various neurological problems.

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    Related Documents

    Physiology of CNS MCQ PDF

    Description

    Explore the intricate workings of central nervous system sensory receptors in this quiz. Learn about the types of stimuli, receptor potentials, and the differences between slowly and rapidly adapting receptors. Test your understanding of how these receptors function and their role in our sensory experiences.

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