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Questions and Answers
What are the two major subdivisions of the nervous system?
What are the two major subdivisions of the nervous system?
Central nervous system (CNS) and peripheral nervous system (PNS)
What is the function of the central nervous system (CNS)?
What is the function of the central nervous system (CNS)?
The CNS processes incoming sensory information and serves as the source of thoughts, emotions, and memories. It also sends signals that stimulate muscle contraction and gland secretion.
What is the role of the spinal cord?
What is the role of the spinal cord?
The spinal cord connects the brain to the rest of the body and is responsible for transmitting sensory information to the brain and motor signals from the brain to the muscles and glands.
What are the two divisions of the peripheral nervous system (PNS)?
What are the two divisions of the peripheral nervous system (PNS)?
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What are nerves?
What are nerves?
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What is the function of sensory receptors?
What is the function of sensory receptors?
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What is the function of the afferent division of the PNS?
What is the function of the afferent division of the PNS?
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Give some examples of somatic senses.
Give some examples of somatic senses.
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What are the special senses?
What are the special senses?
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What are the two subdivisions of the efferent division?
What are the two subdivisions of the efferent division?
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What is the function of the somatic nervous system?
What is the function of the somatic nervous system?
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What is the function of the autonomic nervous system?
What is the function of the autonomic nervous system?
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What are the three subdivisions of the autonomic nervous system?
What are the three subdivisions of the autonomic nervous system?
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What is the general relationship between the parasympathetic and sympathetic nervous systems?
What is the general relationship between the parasympathetic and sympathetic nervous systems?
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Give an example of how the parasympathetic and sympathetic systems have opposing effects.
Give an example of how the parasympathetic and sympathetic systems have opposing effects.
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What are the three main functions of the nervous system?
What are the three main functions of the nervous system?
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What is the function of sensory neurons?
What is the function of sensory neurons?
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What is the function of interneurons?
What is the function of interneurons?
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What are neuroglia?
What are neuroglia?
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Why are neuroglia important?
Why are neuroglia important?
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What are astrocytes?
What are astrocytes?
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What is the role of astrocytes in the blood-brain barrier?
What is the role of astrocytes in the blood-brain barrier?
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What is the function of oligodendrocytes?
What is the function of oligodendrocytes?
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What is the function of microglia?
What is the function of microglia?
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What is the function of ependymal cells?
What is the function of ependymal cells?
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What is the function of Schwann cells?
What is the function of Schwann cells?
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What is the myelin sheath?
What is the myelin sheath?
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What is myelination?
What is myelination?
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What is the difference between myelination in the CNS and PNS?
What is the difference between myelination in the CNS and PNS?
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Differentiate between white and gray matter in the brain.
Differentiate between white and gray matter in the brain.
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How do neurons and muscle fibers communicate with each other?
How do neurons and muscle fibers communicate with each other?
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What is the role of action potentials in neuron and muscle fiber communication?
What is the role of action potentials in neuron and muscle fiber communication?
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Explain the process of sensory information processing.
Explain the process of sensory information processing.
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Describe the process of generating a motor response.
Describe the process of generating a motor response.
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What are the two factors involved in the production of electrical signals in neurons and muscle fibers?
What are the two factors involved in the production of electrical signals in neurons and muscle fibers?
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What is the role of ion channels in the production of electrical signals?
What is the role of ion channels in the production of electrical signals?
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What is the difference between leak channels, ligand-gated channels, and voltage-gated channels?
What is the difference between leak channels, ligand-gated channels, and voltage-gated channels?
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What is resting membrane potential?
What is resting membrane potential?
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Study Notes
Nervous System Organization
- Composed of nervous tissues, divided into Central Nervous System (CNS) and Peripheral Nervous System (PNS)
Central Nervous System (CNS)
- Includes brain and spinal cord
- Processes sensory information
- Source of thoughts, emotions, memories
- Initiates muscle contractions and gland secretions
Spinal Cord
- Attached to the brain
- Enclosed by the vertebral column
Peripheral Nervous System (PNS)
- Nervous tissues outside the CNS
- Includes nerves and sensory receptors
- Divided into afferent and efferent divisions
Nerves
- Bundles of axons
- Located outside the brain and spinal cord
Sensory Receptors
- Structures that detect changes in the environment (external or internal)
Afferent Division
- Carries sensory information from sensory receptors to the CNS
- Includes somatic senses (touch, temperature, pain, body position) and special senses (smell, taste, vision, hearing, balance)
Efferent Division
- Carries motor commands from the CNS to effectors (muscles and glands)
- Divided into somatic and autonomic nervous systems
Somatic Nervous System
- Part of efferent division
- Controls skeletal muscles
- Voluntary responses
Autonomic Nervous System
- Part of efferent division
- Controls smooth, cardiac muscles, and glands
- Involuntary responses
ANS Subdivisions
- Parasympathetic: "rest and digest," calming the body
- Sympathetic: "fight or flight," preparing the body for stressful situations
- Enteric: controls the GI tract; can function independently but communicates with other ANS branches
Parasympathetic vs. Sympathetic
- Opposite actions (e.g., sympathetic speeds heart rate, parasympathetic slows it)
- Parasympathetic promotes relaxation and digestion; sympathetic prepares for emergencies
Enteric Nervous System
- Subdivision of the autonomic nervous system
- Regulates activity of smooth muscles and glands in the gastrointestinal tract
- Can function independently, but communicates with the other branches of the autonomic nervous system
Nervous System Functions
- Sensory function: detects stimuli, transmits to CNS
- Integrative function: processes information, determines appropriate response
- Motor function: elicits response, transmits to effectors
Neurons (Nerve Cells)
- Basic functional unit of the nervous system
- Responsible for sensing, thinking, remembering, muscle control, and gland secretion
Neuron Components
- Dendrites: receive signals, input portion
- Cell body (soma): contains organelles, control center, input portion
- Axon: generates action potentials, output portion
- Axon hillock: trigger zone for action potential generation
- Axon collaterals: branches of the axon
- Axon terminals: end of axon branches, form synapses
Ganglia and Nuclei
- Ganglia: clusters of neuron cell bodies in the PNS
- Nuclei: clusters of neuron cell bodies in the CNS
Axon Terminals/Synaptic End Bulbs
- Contain synaptic vesicles with neurotransmitters
- Release neurotransmitters into synapses (spaces between neurons or other cells)
Neuronal Communication
- Action potential arrives at synaptic end bulb
- Neurotransmitters released, influencing target cells
Axonal Transport
- Moves materials between cell body and axon terminals
- Anterograde: moves material forward (cell body to terminals, using kinesin)
- Retrograde: moves material backward (terminals to cell body, using dynein)
Sensory Neurons
- Part of afferent division
- One axon extends from cell body with dendrites at the periphery
- Sensory receptors are either dendrites or adjacent structures
Motor Neurons
- Part of efferent division
- Carry signals from CNS to effectors
- Most have one axon and dendrites
- Divided into somatic and autonomic motor neurons
Interneurons
- Located within the CNS
- Connect sensory and motor neurons
- Process information and mediate responses
Neuroglia
- Supporting cells in the nervous system
- Nourish, protect, maintain homeostasis
- Do not generate action potentials, but can divide/grow
Neuroglia Types
- Astrocytes: most abundant, surround blood vessels, help maintain blood-brain barrier
- Oligodendrocytes: form myelin sheaths in CNS
- Microglia: remove cellular debris
- Ependymal cells: line ventricles, produce and circulate cerebrospinal fluid
- Schwann cells: form myelin sheaths in PNS; important in axonal regeneration
Myelin Sheath
- Multilayered lipid/protein covering axons
- Insulates axons, speeds action potential conduction
Myelination (CNS vs. PNS)
- CNS: one oligodendrocyte can myelinate multiple axon segments
- PNS: one Schwann cell myelinates one axon segment
White and Gray Matter
- White matter: mainly myelinated axons
- Gray matter: cell bodies, dendrites, unmyelinated axons, axon terminals, neuroglia
Electrical Signals in Neurons
- Graded potentials: short-distance signals
- Action potentials: long-distance signals; combination of depolarization and repolarization
Action Potential Mechanism
- Depolarization phase: sodium channels open, influx of Na+
- Repolarization phase: potassium channels open, outflow of K+
- After-hyperpolarization: potassium channels remain open for a time
- Threshold: minimum depolarization required to initiate action potential
Factors Affecting Action Potential Velocity
- Axon diameter: larger diameter, faster conduction
- Myelination: myelin speeds conduction (saltatory conduction)
Classification of Neurons
- A fibers: myelinated, fast; sensory and motor
- C fibers: unmyelated, slow; sensory and motor
Synaptic Communication
-
Chemical synapse: neurotransmitters released; slower but more complex
- Steps: AP arrival, Ca2+ influx, neurotransmitter release, binding to receptors, postsynaptic potential, signal termination
- Electrical synapse: direct ion flow; faster ( gap junctions)
Postsynaptic Potentials
- EPSP (excitatory): depolarization, increase chance of action potential
- IPSP (inhibitory): hyperpolarization, decrease chance of action potential
Summation of Postsynaptic Potentials
- Temporal summation: multiple EPSPs or IPSPs occur in rapid succession
- Spatial summation: multiple EPSPs or IPSPs from different synapses occur at the same time
Neurotransmitter Effects
- Can be excitatory or inhibitory
- Can affect target cell in various ways (e.g., synthesizing proteins, changing ion concentrations)
Neurotransmitter Receptors
- Ionotropic receptors: ligand-gated channels
- Metabotropic receptors: involve G proteins
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Description
Explore the complex organization of the nervous system, including the Central Nervous System (CNS) and Peripheral Nervous System (PNS). Understand the roles of the brain, spinal cord, sensory receptors, and the divisions of nerves that facilitate sensory and motor functions.