Nervous System Organization
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Questions and Answers

What are the two major subdivisions of the nervous system?

Central nervous system (CNS) and peripheral nervous system (PNS)

What is the function of the central nervous system (CNS)?

The CNS processes incoming sensory information and serves as the source of thoughts, emotions, and memories. It also sends signals that stimulate muscle contraction and gland secretion.

What is the role of the spinal cord?

The spinal cord connects the brain to the rest of the body and is responsible for transmitting sensory information to the brain and motor signals from the brain to the muscles and glands.

What are the two divisions of the peripheral nervous system (PNS)?

<p>Afferent division and efferent division</p> Signup and view all the answers

What are nerves?

<p>Nerves are bundles of axons that lie outside the brain and spinal cord.</p> Signup and view all the answers

What is the function of sensory receptors?

<p>Sensory receptors monitor changes in the external or internal environment.</p> Signup and view all the answers

What is the function of the afferent division of the PNS?

<p>The afferent division carries sensory information from the body to the CNS.</p> Signup and view all the answers

Give some examples of somatic senses.

<p>Tactile (touch), thermal (temperature), pain, and proprioceptive (position and movement of joints) sensations</p> Signup and view all the answers

What are the special senses?

<p>Smell, taste, vision, hearing, and equilibrium</p> Signup and view all the answers

What are the two subdivisions of the efferent division?

<p>Somatic nervous system and autonomic nervous system</p> Signup and view all the answers

What is the function of the somatic nervous system?

<p>The somatic nervous system controls voluntary movements of skeletal muscles.</p> Signup and view all the answers

What is the function of the autonomic nervous system?

<p>The autonomic nervous system controls involuntary actions of smooth muscles, cardiac muscles, and glands.</p> Signup and view all the answers

What are the three subdivisions of the autonomic nervous system?

<p>Parasympathetic nervous system, sympathetic nervous system, and enteric nervous system</p> Signup and view all the answers

What is the general relationship between the parasympathetic and sympathetic nervous systems?

<p>They have opposite effects on the body.</p> Signup and view all the answers

Give an example of how the parasympathetic and sympathetic systems have opposing effects.

<p>The sympathetic nervous system increases heart rate, while the parasympathetic nervous system slows down the heart rate.</p> Signup and view all the answers

What are the three main functions of the nervous system?

<p>Sensory function, integrative function, and motor function</p> Signup and view all the answers

What is the function of sensory neurons?

<p>Sensory neurons transmit action potentials from sensory receptors to the CNS.</p> Signup and view all the answers

What is the function of interneurons?

<p>Interneurons process information from sensory neurons and activate appropriate motor neurons.</p> Signup and view all the answers

What are neuroglia?

<p>Neuroglia are supporting cells that nourish, protect, and maintain homeostasis for neurons.</p> Signup and view all the answers

Why are neuroglia important?

<p>They are essential for the proper functioning of neurons and the nervous system as a whole.</p> Signup and view all the answers

What are astrocytes?

<p>Astrocytes are the most abundant type of neuroglia in the CNS and they perform a variety of functions, including supporting and nourishing neurons.</p> Signup and view all the answers

What is the role of astrocytes in the blood-brain barrier?

<p>Astrocytes secrete chemicals that maintain the tightness of tight junctions in the blood-brain barrier, isolating neurons in the CNS from harmful substances.</p> Signup and view all the answers

What is the function of oligodendrocytes?

<p>Oligodendrocytes form and maintain the myelin sheath around axons in the CNS.</p> Signup and view all the answers

What is the function of microglia?

<p>Microglia are the phagocytic cells of the CNS that remove cellular debris and pathogens.</p> Signup and view all the answers

What is the function of ependymal cells?

<p>Ependymal cells line the ventricles of the brain and central canal of the spinal cord, producing and circulating cerebrospinal fluid.</p> Signup and view all the answers

What is the function of Schwann cells?

<p>Schwann cells form and maintain the myelin sheath around axons in the PNS.</p> Signup and view all the answers

What is the myelin sheath?

<p>The myelin sheath is a multilayer covering of lipids and proteins that insulates axons.</p> Signup and view all the answers

What is myelination?

<p>Myelination is the process of forming the myelin sheath around axons.</p> Signup and view all the answers

What is the difference between myelination in the CNS and PNS?

<p>In the PNS, one Schwann cell wraps around one segment of an axon, whereas in the CNS, one oligodendrocyte can wrap around multiple axons.</p> Signup and view all the answers

Differentiate between white and gray matter in the brain.

<p>White matter is mainly composed of myelinated axons, while gray matter is composed of cell bodies, dendrites, unmyelinated axons, axon terminals, and neuroglia.</p> Signup and view all the answers

How do neurons and muscle fibers communicate with each other?

<p>Neurons and muscle fibers communicate through electrical signals, including graded potentials and action potentials.</p> Signup and view all the answers

What is the role of action potentials in neuron and muscle fiber communication?

<p>Action potentials cause neurons to release neurotransmitters and muscle fibers to contract.</p> Signup and view all the answers

Explain the process of sensory information processing.

<p>Sensory information is processed through a series of steps, starting with a graded potential in the sensory receptor, then an action potential traveling along the sensory neuron to the CNS, followed by activation of interneurons in the CNS, and finally interpretation of the stimuli in the cerebral cortex.</p> Signup and view all the answers

Describe the process of generating a motor response.

<p>A stimuli in the brain leads to the generation of action potentials in upper motor neurons, which then activate lower motor neurons. The action potentials in lower motor neurons release neurotransmitters at the neuromuscular junction, causing skeletal muscle contraction and a motor response.</p> Signup and view all the answers

What are the two factors involved in the production of electrical signals in neurons and muscle fibers?

<p>The presence of specific ion channels and the existence of resting membrane potential</p> Signup and view all the answers

What is the role of ion channels in the production of electrical signals?

<p>Ion channels allow ions to move across the cell membrane, creating a flow of electrical current that changes the membrane potential.</p> Signup and view all the answers

What is the difference between leak channels, ligand-gated channels, and voltage-gated channels?

<p>Leak channels are always open and allow for a continuous flow of ions, ligand-gated channels open in response to the binding of a specific ligand, and voltage-gated channels open in response to changes in membrane potential.</p> Signup and view all the answers

What is resting membrane potential?

<p>Resting membrane potential is the electrical charge difference across the cell membrane when the cell is at rest.</p> Signup and view all the answers

Study Notes

Nervous System Organization

  • Composed of nervous tissues, divided into Central Nervous System (CNS) and Peripheral Nervous System (PNS)

Central Nervous System (CNS)

  • Includes brain and spinal cord
  • Processes sensory information
  • Source of thoughts, emotions, memories
  • Initiates muscle contractions and gland secretions

Spinal Cord

  • Attached to the brain
  • Enclosed by the vertebral column

Peripheral Nervous System (PNS)

  • Nervous tissues outside the CNS
  • Includes nerves and sensory receptors
  • Divided into afferent and efferent divisions

Nerves

  • Bundles of axons
  • Located outside the brain and spinal cord

Sensory Receptors

  • Structures that detect changes in the environment (external or internal)

Afferent Division

  • Carries sensory information from sensory receptors to the CNS
  • Includes somatic senses (touch, temperature, pain, body position) and special senses (smell, taste, vision, hearing, balance)

Efferent Division

  • Carries motor commands from the CNS to effectors (muscles and glands)
  • Divided into somatic and autonomic nervous systems

Somatic Nervous System

  • Part of efferent division
  • Controls skeletal muscles
  • Voluntary responses

Autonomic Nervous System

  • Part of efferent division
  • Controls smooth, cardiac muscles, and glands
  • Involuntary responses

ANS Subdivisions

  • Parasympathetic: "rest and digest," calming the body
  • Sympathetic: "fight or flight," preparing the body for stressful situations
  • Enteric: controls the GI tract; can function independently but communicates with other ANS branches

Parasympathetic vs. Sympathetic

  • Opposite actions (e.g., sympathetic speeds heart rate, parasympathetic slows it)
  • Parasympathetic promotes relaxation and digestion; sympathetic prepares for emergencies

Enteric Nervous System

  • Subdivision of the autonomic nervous system
  • Regulates activity of smooth muscles and glands in the gastrointestinal tract
  • Can function independently, but communicates with the other branches of the autonomic nervous system

Nervous System Functions

  • Sensory function: detects stimuli, transmits to CNS
  • Integrative function: processes information, determines appropriate response
  • Motor function: elicits response, transmits to effectors

Neurons (Nerve Cells)

  • Basic functional unit of the nervous system
  • Responsible for sensing, thinking, remembering, muscle control, and gland secretion

Neuron Components

  • Dendrites: receive signals, input portion
  • Cell body (soma): contains organelles, control center, input portion
  • Axon: generates action potentials, output portion
    • Axon hillock: trigger zone for action potential generation
    • Axon collaterals: branches of the axon
    • Axon terminals: end of axon branches, form synapses

Ganglia and Nuclei

  • Ganglia: clusters of neuron cell bodies in the PNS
  • Nuclei: clusters of neuron cell bodies in the CNS

Axon Terminals/Synaptic End Bulbs

  • Contain synaptic vesicles with neurotransmitters
  • Release neurotransmitters into synapses (spaces between neurons or other cells)

Neuronal Communication

  • Action potential arrives at synaptic end bulb
  • Neurotransmitters released, influencing target cells

Axonal Transport

  • Moves materials between cell body and axon terminals
  • Anterograde: moves material forward (cell body to terminals, using kinesin)
  • Retrograde: moves material backward (terminals to cell body, using dynein)

Sensory Neurons

  • Part of afferent division
  • One axon extends from cell body with dendrites at the periphery
  • Sensory receptors are either dendrites or adjacent structures

Motor Neurons

  • Part of efferent division
  • Carry signals from CNS to effectors
  • Most have one axon and dendrites
  • Divided into somatic and autonomic motor neurons

Interneurons

  • Located within the CNS
  • Connect sensory and motor neurons
  • Process information and mediate responses

Neuroglia

  • Supporting cells in the nervous system
  • Nourish, protect, maintain homeostasis
  • Do not generate action potentials, but can divide/grow

Neuroglia Types

  • Astrocytes: most abundant, surround blood vessels, help maintain blood-brain barrier
  • Oligodendrocytes: form myelin sheaths in CNS
  • Microglia: remove cellular debris
  • Ependymal cells: line ventricles, produce and circulate cerebrospinal fluid
  • Schwann cells: form myelin sheaths in PNS; important in axonal regeneration

Myelin Sheath

  • Multilayered lipid/protein covering axons
  • Insulates axons, speeds action potential conduction

Myelination (CNS vs. PNS)

  • CNS: one oligodendrocyte can myelinate multiple axon segments
  • PNS: one Schwann cell myelinates one axon segment

White and Gray Matter

  • White matter: mainly myelinated axons
  • Gray matter: cell bodies, dendrites, unmyelinated axons, axon terminals, neuroglia

Electrical Signals in Neurons

  • Graded potentials: short-distance signals
  • Action potentials: long-distance signals; combination of depolarization and repolarization

Action Potential Mechanism

  • Depolarization phase: sodium channels open, influx of Na+
  • Repolarization phase: potassium channels open, outflow of K+
  • After-hyperpolarization: potassium channels remain open for a time
  • Threshold: minimum depolarization required to initiate action potential

Factors Affecting Action Potential Velocity

  • Axon diameter: larger diameter, faster conduction
  • Myelination: myelin speeds conduction (saltatory conduction)

Classification of Neurons

  • A fibers: myelinated, fast; sensory and motor
  • C fibers: unmyelated, slow; sensory and motor

Synaptic Communication

  • Chemical synapse: neurotransmitters released; slower but more complex
    • Steps: AP arrival, Ca2+ influx, neurotransmitter release, binding to receptors, postsynaptic potential, signal termination
  • Electrical synapse: direct ion flow; faster ( gap junctions)

Postsynaptic Potentials

  • EPSP (excitatory): depolarization, increase chance of action potential
  • IPSP (inhibitory): hyperpolarization, decrease chance of action potential

Summation of Postsynaptic Potentials

  • Temporal summation: multiple EPSPs or IPSPs occur in rapid succession
  • Spatial summation: multiple EPSPs or IPSPs from different synapses occur at the same time

Neurotransmitter Effects

  • Can be excitatory or inhibitory
  • Can affect target cell in various ways (e.g., synthesizing proteins, changing ion concentrations)

Neurotransmitter Receptors

  • Ionotropic receptors: ligand-gated channels
  • Metabotropic receptors: involve G proteins

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Explore the complex organization of the nervous system, including the Central Nervous System (CNS) and Peripheral Nervous System (PNS). Understand the roles of the brain, spinal cord, sensory receptors, and the divisions of nerves that facilitate sensory and motor functions.

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