Physiology Chapter 1 Quiz

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Questions and Answers

Which of the following are examples of pyrimidines?

  • Guanine, Adenine, Thymine
  • Adenine, Cytosine, Guanine
  • Uracil, Guanine, Cytosine
  • Cytosine, Thymine, Uracil (correct)

Deoxyribose is a five-carbon sugar that contains oxygen.

False (B)

What is the name of the bond that forms between a nitrogenous base and a five-carbon sugar in a nucleotide?

N-glycosidic bond

The ______ of a solution is the amount of solute per unit volume of solution.

<p>concentration</p> Signup and view all the answers

Match the following terms with their definitions:

<p>Solute = The liquid into which solutes dissolve Solvent = Any substance that dissolves in a liquid Solution = The combination of solutes dissolved in a solvent Concentration = The degree to which a molecule is able to dissolve in a solvent</p> Signup and view all the answers

What is the primary function of the Smooth ER?

<p>Synthesis of lipids (D)</p> Signup and view all the answers

Homeostasis refers to a constant state of equilibrium within the body.

<p>False (B)</p> Signup and view all the answers

What are the two main fluid compartments found within the human body?

<p>Extracellular fluid (ECF) and Intracellular fluid (ICF)</p> Signup and view all the answers

The ______ is a stress hormone that peaks throughout the day.

<p>Cortisol</p> Signup and view all the answers

Match the following experimental design types with their descriptions:

<p>Independent variable = The factor being manipulated or changed in an experiment. Dependent variable = The factor being measured or observed in an experiment. Placebo effect = A positive response to a treatment due to expectation, even if the treatment is inactive. Nocebo effect = A negative response to a treatment due to expectation, even if the treatment is inactive.</p> Signup and view all the answers

Which of the following is NOT a component of the body's excretory system?

<p>Pancreas (B)</p> Signup and view all the answers

A blind study involves both the participant and the administrator being unaware of the treatment being given.

<p>False (B)</p> Signup and view all the answers

What is the main difference between a prospective study and a longitudinal study?

<p>A prospective study follows a group of individuals forward in time, while a longitudinal study can follow a group over an extended period, looking backward and forward.</p> Signup and view all the answers

What is the main role of mitochondria in cells?

<p>Adenosine triphosphate (ATP) production (B)</p> Signup and view all the answers

Apoptosis is a process that allows uncontrolled cell growth in cancer.

<p>False (B)</p> Signup and view all the answers

What is the function of lysosomes?

<p>Break down bacteria and old organelles</p> Signup and view all the answers

Mitochondria are the site of most ________ synthesis in the cell.

<p>ATP</p> Signup and view all the answers

Match the following organelles to their primary functions:

<p>Mitochondria = ATP production Golgi Apparatus = Protein packaging Lysosomes = Digestive enzymes Peroxisomes = Break down fatty acids</p> Signup and view all the answers

Which of the following statements is true about stem cells?

<p>They are undifferentiated cells that can specialize. (D)</p> Signup and view all the answers

The rough endoplasmic reticulum has a smooth appearance due to the absence of ribosomes.

<p>False (B)</p> Signup and view all the answers

What is the role of the Golgi apparatus in the cell?

<p>Protein modification and packaging</p> Signup and view all the answers

Which fluid compartment is high in sodium?

<p>Extracellular fluid (ECF) (D)</p> Signup and view all the answers

Potassium is the high ion found in extracellular fluid (ECF).

<p>False (B)</p> Signup and view all the answers

What is the primary function of the pericardial membrane?

<p>It surrounds and protects the heart.</p> Signup and view all the answers

The interior of any hollow organ is referred to as the ______.

<p>lumen</p> Signup and view all the answers

Match each type of membrane with its corresponding protein percentage:

<p>Red blood cell membrane = 49 percent Myelin membrane = 18 percent Inner mitochondrial membrane = 76 percent</p> Signup and view all the answers

Which type of protein can be removed without disrupting the integrity of the membrane?

<p>Peripheral proteins (B)</p> Signup and view all the answers

Cholesterol molecules are embedded within the lipid bilayer of biological membranes.

<p>True (A)</p> Signup and view all the answers

What percentage of protein is found in the myelin membrane?

<p>18 percent</p> Signup and view all the answers

What is the function of an allosteric activator?

<p>Binds to the protein away from the binding site and activates it (C)</p> Signup and view all the answers

Allosteric inhibitors activate a protein by binding to the active site.

<p>False (B)</p> Signup and view all the answers

What are the four major biomolecules?

<p>Carbohydrates, lipids, proteins, nucleotides</p> Signup and view all the answers

The transfer of electrons between atoms creating charged ions is known as __________ bonds.

<p>ionic</p> Signup and view all the answers

Match the following types of bonds with their descriptions:

<p>Covalent Bonds = Atoms share electrons Ionic Bonds = Transfer of electrons creating charged ions Hydrogen Bonds = Weak attraction between polar molecules Van der Waals Forces = Temporary attractions</p> Signup and view all the answers

Which types of macromolecules store genetic information?

<p>Nucleotides (C)</p> Signup and view all the answers

Down-regulation refers to the increase in the amount of protein in cells.

<p>False (B)</p> Signup and view all the answers

What can affect the reaction rate to reach its maximum?

<p>Concentration of ligand, saturation</p> Signup and view all the answers

Which of the following proteins are primarily involved in cell-matrix junctions?

<p>Integrins (A)</p> Signup and view all the answers

Tight junctions are formed by the protein selectin.

<p>False (B)</p> Signup and view all the answers

What is the main function of desmosomes?

<p>To provide strong adhesion between cells.</p> Signup and view all the answers

____ junctions allow for direct communication between adjacent cells.

<p>Gap</p> Signup and view all the answers

Match the type of cell junction with its main characteristic:

<p>Gap junction = Direct cell communication Tight junction = Prevents leakage between cells Desmosome = Anchors cells together Focal adhesion = Links cells to the extracellular matrix</p> Signup and view all the answers

What type of molecule is primarily responsible for cell-cell adhesion in adherens junctions?

<p>Cadherins (A)</p> Signup and view all the answers

Selectins are involved in permanent cell-cell adhesions.

<p>False (B)</p> Signup and view all the answers

What is the role of integrins in cell junctions?

<p>Integrins facilitate adhesion between cells and the extracellular matrix and are involved in cell signaling.</p> Signup and view all the answers

Flashcards

Physiology

The study of the normal functioning of living organisms and their parts.

Homeostasis

The maintenance of internal stability in an organism despite external changes.

Mass Balance

The principle of keeping inputs and outputs in equilibrium to maintain stability.

Control Systems

Systems in physiology that regulate functions via feedback mechanisms.

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Circadian Rhythm

Biological processes that cycle around a 24-hour period, influencing behaviors like sleep.

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Nocebo Effect

Negative health effects caused by a patient's expectation of harm from treatment.

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Double Blind Study

An experimental design where neither participants nor administrators know who receives the treatment.

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Independent and Dependent Variables

Independent variables are manipulated; dependent variables are measured changes in response.

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Allosteric Activator

A modulator that binds to a protein away from its binding site to activate it.

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Allosteric Inhibitor

A modulator that binds to a protein away from its binding site and inactivates it.

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Up-Regulation

Increase in the number or activity of proteins in cells.

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Down-Regulation

Decrease in the number or activity of proteins in cells.

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Saturation

The point at which increasing ligand concentration no longer increases reaction rate.

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Covalent Bonds

Bonds formed when atoms share electrons.

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Ionic Bonds

Bonds formed through the transfer of electrons, creating charged ions.

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Hydrogen Bonds

Weak attractions between polar molecules.

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Pyrimidines

Nitrogenous bases including cytosine, thymine, and uracil.

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Solute

A substance that dissolves in a liquid to form a solution.

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Solubility

The degree to which a substance dissolves in a solvent.

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Universal Solvent

Water, as it dissolves most substances.

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Affinity

The degree to which a protein binds to its ligand.

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Equilibrium Binding

The state where the rates of binding and unbinding are equal.

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Dissociation Constant (Kd)

A measure indicating how easily a ligand separates from a protein, equals 1/Keq.

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Proteolytic Activation

Activation of a protein by removing peptide fragments.

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Lumen

The interior space within a hollow organ, filled with air or fluid.

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Extracellular Fluid (ECF)

Fluid outside cells, rich in sodium and includes plasma and intestinal fluid.

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Intracellular Fluid (ICF)

Fluid within cells, primarily high in potassium ions.

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Pericardial Sac

A membrane that surrounds the heart, providing protection and cushioning.

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Fluid Mosaic Model

A model describing the structure of biological membranes as a mosaic of diverse protein molecules embedded in a flexible lipid bilayer.

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Transmembrane Proteins

Proteins that span the entire lipid bilayer, aiding in transport and communication.

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Peripheral Proteins

Proteins located on the edges of the membrane that can be removed without damaging it.

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Lipid Bilayer

A double layer of lipids that makes up the cell membrane, with hydrophilic heads facing outwards and hydrophobic tails facing inwards.

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Apoptosis

Programmed cell death that maintains tissue health.

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Stem Cells

Undifferentiated cells that can develop into specialized cell types.

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Mitochondria

Organelles known as the powerhouses of the cell, generating ATP.

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Golgi Apparatus

Cell organelle involved in modifying and packaging proteins.

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Lysosomes

Organelles that contain enzymes to digest waste materials and cellular debris.

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Peroxisomes

Organelles that break down fatty acids and detoxify harmful substances.

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Rough Endoplasmic Reticulum (Rough ER)

Network of membranes dotted with ribosomes, primarily synthesizing proteins.

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Smooth Endoplasmic Reticulum (Smooth ER)

Lipid synthesis site and calcium storage, lacking ribosomes.

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Extracellular Matrix

The network of proteins and molecules that provide structural and biochemical support to surrounding cells.

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Proteoglycans

Glycoproteins that provide structural support in the extracellular matrix.

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Integrins

Membrane proteins that facilitate cell-matrix and cell-cell adhesion by binding collagen and laminin.

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Cell Adhesion Molecules (CAMs)

Proteins located on the cell surface involved in the binding with other cells or the extracellular matrix.

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Gap Junctions

Communicating junctions that allow direct transfer of small molecules and ions between adjacent cells.

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Tight Junctions

Occluding junctions that prevent the passage of materials between cells, often found in the intestines.

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Desmosomes

Anchoring junctions that mechanically attach cells to their neighbors, maintaining tissue integrity.

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Selectins

Proteins that mediate temporary cell-cell adhesions, typically during immune responses.

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Study Notes

Syllabus

  • There is a TA and a tutor
  • Students should have a study group
  • Midterms (20%)
    • Four midterms
    • 9:20-10:20 am
    • One midterm is dropped
  • Comprehensive Final (30%)
  • Attendance (10%)
  • Squarecap
  • Homework
    • Pearson Online (part of the textbook)
    • Homework is due at 11:59 on Friday

Chapter 1 - Physiology

  • Physiology is the study of the normal functioning of a living organism and its component parts, including all its chemical and physical processes.
  • What are BIOSPHERES?
    • Is composed of everything: species and organisms
  • What does this system consist of? (SLIDE 14 omitted)

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