Physiology Chapter 1 Quiz
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Questions and Answers

Which of the following are examples of pyrimidines?

  • Guanine, Adenine, Thymine
  • Adenine, Cytosine, Guanine
  • Uracil, Guanine, Cytosine
  • Cytosine, Thymine, Uracil (correct)
  • Deoxyribose is a five-carbon sugar that contains oxygen.

    False (B)

    What is the name of the bond that forms between a nitrogenous base and a five-carbon sugar in a nucleotide?

    N-glycosidic bond

    The ______ of a solution is the amount of solute per unit volume of solution.

    <p>concentration</p> Signup and view all the answers

    Match the following terms with their definitions:

    <p>Solute = The liquid into which solutes dissolve Solvent = Any substance that dissolves in a liquid Solution = The combination of solutes dissolved in a solvent Concentration = The degree to which a molecule is able to dissolve in a solvent</p> Signup and view all the answers

    What is the primary function of the Smooth ER?

    <p>Synthesis of lipids (D)</p> Signup and view all the answers

    Homeostasis refers to a constant state of equilibrium within the body.

    <p>False (B)</p> Signup and view all the answers

    What are the two main fluid compartments found within the human body?

    <p>Extracellular fluid (ECF) and Intracellular fluid (ICF)</p> Signup and view all the answers

    The ______ is a stress hormone that peaks throughout the day.

    <p>Cortisol</p> Signup and view all the answers

    Match the following experimental design types with their descriptions:

    <p>Independent variable = The factor being manipulated or changed in an experiment. Dependent variable = The factor being measured or observed in an experiment. Placebo effect = A positive response to a treatment due to expectation, even if the treatment is inactive. Nocebo effect = A negative response to a treatment due to expectation, even if the treatment is inactive.</p> Signup and view all the answers

    Which of the following is NOT a component of the body's excretory system?

    <p>Pancreas (B)</p> Signup and view all the answers

    A blind study involves both the participant and the administrator being unaware of the treatment being given.

    <p>False (B)</p> Signup and view all the answers

    What is the main difference between a prospective study and a longitudinal study?

    <p>A prospective study follows a group of individuals forward in time, while a longitudinal study can follow a group over an extended period, looking backward and forward.</p> Signup and view all the answers

    What is the main role of mitochondria in cells?

    <p>Adenosine triphosphate (ATP) production (B)</p> Signup and view all the answers

    Apoptosis is a process that allows uncontrolled cell growth in cancer.

    <p>False (B)</p> Signup and view all the answers

    What is the function of lysosomes?

    <p>Break down bacteria and old organelles</p> Signup and view all the answers

    Mitochondria are the site of most ________ synthesis in the cell.

    <p>ATP</p> Signup and view all the answers

    Match the following organelles to their primary functions:

    <p>Mitochondria = ATP production Golgi Apparatus = Protein packaging Lysosomes = Digestive enzymes Peroxisomes = Break down fatty acids</p> Signup and view all the answers

    Which of the following statements is true about stem cells?

    <p>They are undifferentiated cells that can specialize. (D)</p> Signup and view all the answers

    The rough endoplasmic reticulum has a smooth appearance due to the absence of ribosomes.

    <p>False (B)</p> Signup and view all the answers

    What is the role of the Golgi apparatus in the cell?

    <p>Protein modification and packaging</p> Signup and view all the answers

    Which fluid compartment is high in sodium?

    <p>Extracellular fluid (ECF) (D)</p> Signup and view all the answers

    Potassium is the high ion found in extracellular fluid (ECF).

    <p>False (B)</p> Signup and view all the answers

    What is the primary function of the pericardial membrane?

    <p>It surrounds and protects the heart.</p> Signup and view all the answers

    The interior of any hollow organ is referred to as the ______.

    <p>lumen</p> Signup and view all the answers

    Match each type of membrane with its corresponding protein percentage:

    <p>Red blood cell membrane = 49 percent Myelin membrane = 18 percent Inner mitochondrial membrane = 76 percent</p> Signup and view all the answers

    Which type of protein can be removed without disrupting the integrity of the membrane?

    <p>Peripheral proteins (B)</p> Signup and view all the answers

    Cholesterol molecules are embedded within the lipid bilayer of biological membranes.

    <p>True (A)</p> Signup and view all the answers

    What percentage of protein is found in the myelin membrane?

    <p>18 percent</p> Signup and view all the answers

    What is the function of an allosteric activator?

    <p>Binds to the protein away from the binding site and activates it (C)</p> Signup and view all the answers

    Allosteric inhibitors activate a protein by binding to the active site.

    <p>False (B)</p> Signup and view all the answers

    What are the four major biomolecules?

    <p>Carbohydrates, lipids, proteins, nucleotides</p> Signup and view all the answers

    The transfer of electrons between atoms creating charged ions is known as __________ bonds.

    <p>ionic</p> Signup and view all the answers

    Match the following types of bonds with their descriptions:

    <p>Covalent Bonds = Atoms share electrons Ionic Bonds = Transfer of electrons creating charged ions Hydrogen Bonds = Weak attraction between polar molecules Van der Waals Forces = Temporary attractions</p> Signup and view all the answers

    Which types of macromolecules store genetic information?

    <p>Nucleotides (C)</p> Signup and view all the answers

    Down-regulation refers to the increase in the amount of protein in cells.

    <p>False (B)</p> Signup and view all the answers

    What can affect the reaction rate to reach its maximum?

    <p>Concentration of ligand, saturation</p> Signup and view all the answers

    Which of the following proteins are primarily involved in cell-matrix junctions?

    <p>Integrins (A)</p> Signup and view all the answers

    Tight junctions are formed by the protein selectin.

    <p>False (B)</p> Signup and view all the answers

    What is the main function of desmosomes?

    <p>To provide strong adhesion between cells.</p> Signup and view all the answers

    ____ junctions allow for direct communication between adjacent cells.

    <p>Gap</p> Signup and view all the answers

    Match the type of cell junction with its main characteristic:

    <p>Gap junction = Direct cell communication Tight junction = Prevents leakage between cells Desmosome = Anchors cells together Focal adhesion = Links cells to the extracellular matrix</p> Signup and view all the answers

    What type of molecule is primarily responsible for cell-cell adhesion in adherens junctions?

    <p>Cadherins (A)</p> Signup and view all the answers

    Selectins are involved in permanent cell-cell adhesions.

    <p>False (B)</p> Signup and view all the answers

    What is the role of integrins in cell junctions?

    <p>Integrins facilitate adhesion between cells and the extracellular matrix and are involved in cell signaling.</p> Signup and view all the answers

    Flashcards

    Physiology

    The study of the normal functioning of living organisms and their parts.

    Homeostasis

    The maintenance of internal stability in an organism despite external changes.

    Mass Balance

    The principle of keeping inputs and outputs in equilibrium to maintain stability.

    Control Systems

    Systems in physiology that regulate functions via feedback mechanisms.

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    Circadian Rhythm

    Biological processes that cycle around a 24-hour period, influencing behaviors like sleep.

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    Nocebo Effect

    Negative health effects caused by a patient's expectation of harm from treatment.

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    Double Blind Study

    An experimental design where neither participants nor administrators know who receives the treatment.

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    Independent and Dependent Variables

    Independent variables are manipulated; dependent variables are measured changes in response.

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    Allosteric Activator

    A modulator that binds to a protein away from its binding site to activate it.

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    Allosteric Inhibitor

    A modulator that binds to a protein away from its binding site and inactivates it.

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    Up-Regulation

    Increase in the number or activity of proteins in cells.

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    Down-Regulation

    Decrease in the number or activity of proteins in cells.

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    Saturation

    The point at which increasing ligand concentration no longer increases reaction rate.

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    Covalent Bonds

    Bonds formed when atoms share electrons.

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    Ionic Bonds

    Bonds formed through the transfer of electrons, creating charged ions.

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    Hydrogen Bonds

    Weak attractions between polar molecules.

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    Pyrimidines

    Nitrogenous bases including cytosine, thymine, and uracil.

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    Solute

    A substance that dissolves in a liquid to form a solution.

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    Solubility

    The degree to which a substance dissolves in a solvent.

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    Universal Solvent

    Water, as it dissolves most substances.

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    Affinity

    The degree to which a protein binds to its ligand.

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    Equilibrium Binding

    The state where the rates of binding and unbinding are equal.

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    Dissociation Constant (Kd)

    A measure indicating how easily a ligand separates from a protein, equals 1/Keq.

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    Proteolytic Activation

    Activation of a protein by removing peptide fragments.

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    Lumen

    The interior space within a hollow organ, filled with air or fluid.

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    Extracellular Fluid (ECF)

    Fluid outside cells, rich in sodium and includes plasma and intestinal fluid.

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    Intracellular Fluid (ICF)

    Fluid within cells, primarily high in potassium ions.

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    Pericardial Sac

    A membrane that surrounds the heart, providing protection and cushioning.

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    Fluid Mosaic Model

    A model describing the structure of biological membranes as a mosaic of diverse protein molecules embedded in a flexible lipid bilayer.

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    Transmembrane Proteins

    Proteins that span the entire lipid bilayer, aiding in transport and communication.

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    Peripheral Proteins

    Proteins located on the edges of the membrane that can be removed without damaging it.

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    Lipid Bilayer

    A double layer of lipids that makes up the cell membrane, with hydrophilic heads facing outwards and hydrophobic tails facing inwards.

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    Apoptosis

    Programmed cell death that maintains tissue health.

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    Stem Cells

    Undifferentiated cells that can develop into specialized cell types.

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    Mitochondria

    Organelles known as the powerhouses of the cell, generating ATP.

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    Golgi Apparatus

    Cell organelle involved in modifying and packaging proteins.

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    Lysosomes

    Organelles that contain enzymes to digest waste materials and cellular debris.

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    Peroxisomes

    Organelles that break down fatty acids and detoxify harmful substances.

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    Rough Endoplasmic Reticulum (Rough ER)

    Network of membranes dotted with ribosomes, primarily synthesizing proteins.

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    Smooth Endoplasmic Reticulum (Smooth ER)

    Lipid synthesis site and calcium storage, lacking ribosomes.

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    Extracellular Matrix

    The network of proteins and molecules that provide structural and biochemical support to surrounding cells.

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    Proteoglycans

    Glycoproteins that provide structural support in the extracellular matrix.

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    Integrins

    Membrane proteins that facilitate cell-matrix and cell-cell adhesion by binding collagen and laminin.

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    Cell Adhesion Molecules (CAMs)

    Proteins located on the cell surface involved in the binding with other cells or the extracellular matrix.

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    Gap Junctions

    Communicating junctions that allow direct transfer of small molecules and ions between adjacent cells.

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    Tight Junctions

    Occluding junctions that prevent the passage of materials between cells, often found in the intestines.

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    Desmosomes

    Anchoring junctions that mechanically attach cells to their neighbors, maintaining tissue integrity.

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    Selectins

    Proteins that mediate temporary cell-cell adhesions, typically during immune responses.

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    Study Notes

    Syllabus

    • There is a TA and a tutor
    • Students should have a study group
    • Midterms (20%)
      • Four midterms
      • 9:20-10:20 am
      • One midterm is dropped
    • Comprehensive Final (30%)
    • Attendance (10%)
    • Squarecap
    • Homework
      • Pearson Online (part of the textbook)
      • Homework is due at 11:59 on Friday

    Chapter 1 - Physiology

    • Physiology is the study of the normal functioning of a living organism and its component parts, including all its chemical and physical processes.
    • What are BIOSPHERES?
      • Is composed of everything: species and organisms
    • What does this system consist of? (SLIDE 14 omitted)

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    Test your knowledge on the basic concepts of physiology with a focus on biospheres and their components. This quiz assesses your understanding of the normal functioning of living organisms as outlined in Chapter 1. Prepare to explore the essential chemical and physical processes involved in physiology.

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