Physiology Chapter 1 Quiz

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Questions and Answers

Which type of junction prevents the movement of material between cells?

  • Desmosomes
  • Occluding Junctions (correct)
  • Anchoring Junctions
  • Communicating Junctions

The basal lamina is a cellular layer secreted by the epithelial cells.

False (B)

What are the two proteins found on the surface of cells in the second cross-section?

Claudin and Occludin

The disappearance of anchoring junctions can contribute to ___________, a process where cancer cells spread to other parts of the body.

<p>metastasis</p> Signup and view all the answers

Match the following epithelial tissue characteristics with their corresponding descriptions:

<p>Simple = One layer of cells Stratified = Multiple layers of cells Squamous = Flattened cells Cuboidal = Cube-shaped cells Columnar = Tall, column-shaped cells</p> Signup and view all the answers

Epithelial tissue can be categorized based on the number of cell layers and the shape of the cells.

<p>True (A)</p> Signup and view all the answers

Which of the following is NOT a function of epithelial tissue?

<p>Muscle contraction (C)</p> Signup and view all the answers

What is the name of the acellular matrix layer that epithelial cells attach to?

<p>Basal lamina (or Basement membrane)</p> Signup and view all the answers

Which of the following biomolecules are responsible for storing and transmitting genetic information?

<p>Nucleic Acids (D)</p> Signup and view all the answers

Hydrogen bonds are stronger than covalent bonds.

<p>False (B)</p> Signup and view all the answers

What is the primary function of lipids in the body?

<p>Energy storage and membrane structure</p> Signup and view all the answers

The ______ buffer system helps maintain the pH balance of blood.

<p>bicarbonate</p> Signup and view all the answers

Match the following body cavities with their locations:

<p>Cranial cavity = Head Thoracic cavity = Chest Abdominopelvic cavity = Lower torso</p> Signup and view all the answers

Which of the following is NOT a body fluid compartment?

<p>Muscles (C)</p> Signup and view all the answers

Mutations in DNA can lead to genetic disorders like cystic fibrosis.

<p>True (A)</p> Signup and view all the answers

Explain the role of buffers in maintaining pH balance within the body.

<p>Buffers help maintain pH balance by absorbing excess H+ ions (acidic) or OH- ions (basic). They prevent drastic changes in pH, ensuring that the body stays within a healthy range.</p> Signup and view all the answers

The body's ability to maintain stable conditions is known as ______.

<p>homeostasis</p> Signup and view all the answers

Positive feedback mechanisms amplify physiological responses.

<p>True (A)</p> Signup and view all the answers

Which of the following is NOT an example of a lipid?

<p>Carbohydrate (B)</p> Signup and view all the answers

What is the primary function of thromboxanes?

<p>Thromboxanes are involved in blood clot formation (thrombosis).</p> Signup and view all the answers

Match the following terms with their corresponding definitions:

<p>Monosaccharide = A simple sugar, e.g., glucose Polysaccharide = A complex carbohydrate made up of many sugar units Saturated fatty acid = A fatty acid with all single bonds between carbon atoms Unsaturated fatty acid = A fatty acid with at least one double bond between carbon atoms</p> Signup and view all the answers

The molecule ______ serves as the backbone for most lipids.

<p>glycerol</p> Signup and view all the answers

Humans can easily digest cellulose.

<p>False (B)</p> Signup and view all the answers

What is the significance of the R-group in an amino acid?

<p>The R-group determines the unique chemical properties of each amino acid.</p> Signup and view all the answers

Which of these is NOT a major body cavity?

<p>Pelvic (C)</p> Signup and view all the answers

The cell membrane is selectively permeable, meaning it allows some substances to pass through while blocking others.

<p>True (A)</p> Signup and view all the answers

What is the primary function of mitochondria?

<p>ATP (adenosine triphosphate) production</p> Signup and view all the answers

The ______ is a network of interconnected membranes involved in lipid synthesis.

<p>smooth endoplasmic reticulum</p> Signup and view all the answers

Match the type of cell junction with its primary function:

<p>Gap junctions = Provide strength and support between cells Tight junctions = Form a barrier, preventing leaks between cells Anchoring junctions = Allow direct communication between cells through channels</p> Signup and view all the answers

Which type of epithelial tissue is specialized for transporting substances?

<p>Transporting (D)</p> Signup and view all the answers

Skeletal muscle is responsible for involuntary movements, such as heart contractions.

<p>False (B)</p> Signup and view all the answers

What are the three types of cytoskeletal fibers, ranked from smallest to largest?

<p>Actin (microfilaments), intermediate filaments, microtubules</p> Signup and view all the answers

Which of the following are pyrimidines?

<p>Cytosine (A), Thymine (D)</p> Signup and view all the answers

Deoxyribose is a five-carbon sugar that contains oxygen.

<p>False (B)</p> Signup and view all the answers

What is the universal solvent in biological solutions?

<p>Water</p> Signup and view all the answers

The concentration of a solution is the amount of ______ per unit volume of solution.

<p>solute</p> Signup and view all the answers

Which of the following best describes how the pH scale relates to alkalinity?

<p>A pH above 7 is considered alkaline (C)</p> Signup and view all the answers

Match the following terms with their definitions.

<p>Solute = The liquid into which solutes dissolve. Solvent = Any substance that dissolves in a liquid. Solution = The combination of solutes dissolved in a solvent. Concentration = The amount of solute per unit volume of solution.</p> Signup and view all the answers

A protein's affinity for a ligand determines how strongly it binds to that ligand.

<p>True (A)</p> Signup and view all the answers

What is the name of the model that describes the interaction between proteins and ligands, in which the binding site changes its shape to better fit the ligand?

<p>Induced fit</p> Signup and view all the answers

What are the main components of the cell membrane?

<p>Cholesterol, phospholipids, sphingolipids, carbohydrates and proteins (C)</p> Signup and view all the answers

The lipid bilayer of the cell membrane is permeable to all molecules.

<p>False (B)</p> Signup and view all the answers

The ______ is a layer of carbohydrates that surrounds the external surface of the cell, contributing to cell recognition and immune response.

<p>glycocalyx</p> Signup and view all the answers

What are the key functions of microtubules in the cell?

<p>Microtubules play a crucial role in various cellular processes, including intracellular transport, cell division, and structural support. They are involved in the movement of organelles, chromosomes during mitosis, and formation of cilia and flagella.</p> Signup and view all the answers

Match the following cell structures with their functions:

<p>Centrosome = Assembles tubulin monomers into microtubules Centrioles = Direct DNA movement in cell division Cilia = Fluid movement across cells Flagella = Cell movement through fluid</p> Signup and view all the answers

Which of the following is NOT a type of intracellular compartment?

<p>Golgi apparatus (E)</p> Signup and view all the answers

Tau tangles are a primary biomarker of Alzheimer's disease.

<p>True (A)</p> Signup and view all the answers

What is the role of differentiation in cell specialization?

<p>Differentiation involves the activation of specific genes in a cell, leading to the production of proteins and structures that allow the cell to perform a specialized function. This process allows cells to become adapted to different tasks within the body.</p> Signup and view all the answers

Flashcards

Occluding Junctions

Junctions that block material movement between cells, including tight junctions.

Tight Junctions

A type of occluding junction holding cells together, preventing movement of materials between them.

Anchoring Junctions

Junctions that connect cells to each other and to the extracellular matrix.

Desmosome

A specific type of anchoring junction that connects cells together.

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Basal Lamina

An acellular matrix layer secreted by epithelial cells to support tissue.

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Epithelial Tissue

Tissue consisting of one or more layers of cells attached to the basal lamina.

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Cell Adhesion Molecules

Proteins on epithelial cells that help attach them to the basal lamina.

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Types of Epithelia

Classified by layers (simple/stratified) and shapes (squamous, cuboidal, columnar).

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Buffers

Substances that absorb excess H+ or OH- to stabilize pH.

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Proteins

Large biomolecules made of amino acids for structure and function.

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Lipids

Fats and oils used for energy storage and membrane structure.

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Carbohydrates

Sugars and starches that provide quick energy to cells.

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Nucleic Acids

DNA and RNA that store and transmit genetic information.

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Ionic Bonds

Bonds formed between charged atoms (ions).

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Covalent Bonds

Strong bonds where atoms share electrons, like in water.

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Hydrogen Bonds

Weak bonds between molecules, important for biological structures.

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Stem cells

Undifferentiated cells that can divide and develop into specialized cells.

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Organs

Structures made of multiple tissue types working together, e.g., skin.

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Cell membrane

A barrier that regulates exchange and provides structural support.

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Fluid mosaic model

Description of the cell membrane structure with a phospholipid bilayer and embedded proteins.

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Cytoplasm

The material within the cell membrane, excluding the nucleus; includes cytosol, inclusions, and organelles.

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Golgi apparatus

An organelle that packages and ships proteins to their destinations.

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Four main tissue types

Epithelial, connective, muscle, and neural tissues that serve different functions.

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Types of muscle tissue

The three types are skeletal, cardiac, and smooth; each serving different functions in the body.

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Extracellular Fluid

Fluid located outside the cell membrane, surrounding the cells.

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Phospholipids

Molecules forming the lipid bilayer of cell membranes, consisting of a hydrophilic head and hydrophobic tails.

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Cholesterol

A lipid that stabilizes the cell membrane and maintains fluidity.

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Glycoproteins

Proteins with carbohydrate chains attached, serving functions like cell recognition.

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Glycocalyx

A sugary coating on the surface of the cell made of glycoproteins and glycolipids.

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Microtubules

Cylindrical structures that help maintain cell shape and assist in cell division.

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Sphingolipids

A type of lipid that contributes to the structure and function of cell membranes, sticking above the membrane.

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Intracellular Fluid (ICF)

Fluid found inside the cell, crucial for cellular processes.

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Pyrimidines

Nitrogenous bases including cytosine, thymine, and uracil.

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Solute

A substance that dissolves in a liquid to form a solution.

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Solubility

The degree to which a substance can dissolve in a solvent.

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Universal solvent

Water, due to its ability to dissolve many substances.

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Affinity

The degree to which a protein binds to a ligand.

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Equilibrium binding

The rate of a ligand binding equals the rate of unbinding.

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Kd

Dissociation constant; inversely related to binding affinity.

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Proteolytic activation

Activation process requiring removal of peptide fragments.

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Homeostasis

The body's ability to maintain stable conditions.

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Negative Feedback

A process that stabilizes physiological functions.

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Positive Feedback

A mechanism that amplifies physiological responses.

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Set Point

The ideal value for a physiological condition.

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Scientific Method

A systematic approach to experimentation and observation.

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Amino Acids

Building blocks of proteins consisting of an amino group, carboxyl group, and R group.

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Peptide Bond

A bond formed between the amino group of one amino acid and the carboxyl group of another.

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Triglycerides

The form in which more than 90% of lipids exist, composed of glycerol and fatty acids.

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Study Notes

Syllabus

  • There is a TA and a tutor.
  • Students should have study groups.
  • Midterms are 20% of the grade with 4 midterms.
  • Midterms are 9:20-10:20am.
  • One midterm can be dropped.
  • A comprehensive final is worth 30% of the course grade.
  • Attendance is worth 10% of the grade.
  • Homework is available through Pearson Online, part of the textbook.
  • Homework is due at 11:59 on Friday.

Chapter 1: Physiology

  • Physiology is the study of the normal function of a living organism including its chemical and physical processes of its component parts.
  • The biosphere is composed of species and organisms.
  • The materials of the biosphere consist of: (See slide 14)

Additional Study Information

  • Physiology is defined as the study of the normal functioning of a living organism and its component parts.
  • The body systems and their functions are presented in a diagram.
  • A 50-year-old man given an intravenous infusion of glucose at 2 ml per minute with a 50 g/l concentration.
  • Homeostasis maintains internal stability.
  • The process of homeostasis does not mean equilibrium, but a dynamic steady state.
  • Excretion clears substances from the body through kidneys, liver, lungs and skin.
  • There are different ways that the body can regulate itself: local and reflex
  • Biological rhythms are a part of the body (e.g., temperature and cortisol cycle).

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