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Questions and Answers
What percentage of the work of breathing (WOB) is attributed to elastic resistance?
What percentage of the work of breathing (WOB) is attributed to elastic resistance?
Which of the following best describes how airflow limitation typically presents clinically?
Which of the following best describes how airflow limitation typically presents clinically?
Which factor does NOT affect lung compliance?
Which factor does NOT affect lung compliance?
In a container, what occurs to pressure when the volume is increased?
In a container, what occurs to pressure when the volume is increased?
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What is the primary mechanism by which ventilation occurs?
What is the primary mechanism by which ventilation occurs?
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What is the term for the pressure exerted by the gases in the air?
What is the term for the pressure exerted by the gases in the air?
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Which pressure is specifically defined as the pressure within the alveoli?
Which pressure is specifically defined as the pressure within the alveoli?
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What describes the difference between intrapulmonary pressure and intrapleural pressure?
What describes the difference between intrapulmonary pressure and intrapleural pressure?
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What condition is characterized by the presence of air in the pleural space?
What condition is characterized by the presence of air in the pleural space?
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Which of the following pressures would generally increase as altitude decreases?
Which of the following pressures would generally increase as altitude decreases?
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In the context of lung mechanics, which pressure is always negative?
In the context of lung mechanics, which pressure is always negative?
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What would likely occur due to an abnormal communication between the lung and the pleural space?
What would likely occur due to an abnormal communication between the lung and the pleural space?
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Which pressure gradient is crucial for lung expansion during breathing?
Which pressure gradient is crucial for lung expansion during breathing?
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What occurs to the intra-alveolar pressure during inspiration?
What occurs to the intra-alveolar pressure during inspiration?
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What is the relationship between intrapleural pressure and the chest wall during pre-inspiration?
What is the relationship between intrapleural pressure and the chest wall during pre-inspiration?
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Which property of the lung primarily contributes to its ability to recoil?
Which property of the lung primarily contributes to its ability to recoil?
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What happens to the intra-alveolar pressure during expiration?
What happens to the intra-alveolar pressure during expiration?
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Which of the following factors is NOT a property of the lung?
Which of the following factors is NOT a property of the lung?
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Which statement best describes collateral ventilation?
Which statement best describes collateral ventilation?
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What mechanism is responsible for restoring negative pressure in the lung?
What mechanism is responsible for restoring negative pressure in the lung?
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Which physiological change signifies the start of expiration?
Which physiological change signifies the start of expiration?
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What is the primary function of pulmonary surfactant in the alveoli?
What is the primary function of pulmonary surfactant in the alveoli?
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Which type of collateral ventilation involves channels that are 80 - 150 μm in size?
Which type of collateral ventilation involves channels that are 80 - 150 μm in size?
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What condition can result from insufficient pulmonary surfactant in premature infants?
What condition can result from insufficient pulmonary surfactant in premature infants?
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What is implied by the term 'compliance' in relation to lung function?
What is implied by the term 'compliance' in relation to lung function?
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What happens to lung compliance as lung volume approaches extremes?
What happens to lung compliance as lung volume approaches extremes?
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What is the consequence of airway occlusion on collateral ventilation?
What is the consequence of airway occlusion on collateral ventilation?
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What structural components contribute to the elastic recoil of the lungs?
What structural components contribute to the elastic recoil of the lungs?
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What is a significant clinical effect of reduced lung compliance?
What is a significant clinical effect of reduced lung compliance?
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How does aging affect lung compliance?
How does aging affect lung compliance?
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What is the main role of collateral ventilation during airway obstruction?
What is the main role of collateral ventilation during airway obstruction?
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Which positioning method is recommended to expand the affected lung in an adult patient suffering from atelectasis?
Which positioning method is recommended to expand the affected lung in an adult patient suffering from atelectasis?
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Which goal of interventions is primarily associated with the improvement of ventilation and perfusion matching?
Which goal of interventions is primarily associated with the improvement of ventilation and perfusion matching?
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What are the implications of supine versus prone positioning in patients with acute respiratory distress syndrome (ARDS)?
What are the implications of supine versus prone positioning in patients with acute respiratory distress syndrome (ARDS)?
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What is a primary property of lung structures contributing to compliance?
What is a primary property of lung structures contributing to compliance?
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Which statement correctly describes the mechanics of breathing related to pressure changes?
Which statement correctly describes the mechanics of breathing related to pressure changes?
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What is a key indication for the technique known as huffing?
What is a key indication for the technique known as huffing?
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Which of the following would NOT be a goal of positioning a patient during physiotherapy?
Which of the following would NOT be a goal of positioning a patient during physiotherapy?
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In the context of increasing lung compliance, which factor is most significant?
In the context of increasing lung compliance, which factor is most significant?
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What is one of the key phenomena associated with forced expiration in patients with emphysema?
What is one of the key phenomena associated with forced expiration in patients with emphysema?
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What does the Equal Pressure Point (EPP) indicate during forced expiration?
What does the Equal Pressure Point (EPP) indicate during forced expiration?
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Which measurement is primarily used to differentiate between restrictive and obstructive lung diseases?
Which measurement is primarily used to differentiate between restrictive and obstructive lung diseases?
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What occurs when the closing volume of the lungs is reached?
What occurs when the closing volume of the lungs is reached?
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What is the primary purpose of the huffing technique in respiratory therapy?
What is the primary purpose of the huffing technique in respiratory therapy?
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How does aging affect closing volume in the lungs?
How does aging affect closing volume in the lungs?
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Which property of the lungs is characterized by the ability to return to its original shape after being stretched?
Which property of the lungs is characterized by the ability to return to its original shape after being stretched?
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What is a major factor contributing to the turbulence in expiratory flow in patients with severe obstructive lung disease?
What is a major factor contributing to the turbulence in expiratory flow in patients with severe obstructive lung disease?
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During forced expiration from high lung volumes, what is the main outcome of coughing?
During forced expiration from high lung volumes, what is the main outcome of coughing?
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What role does surfactant play in respiratory mechanics?
What role does surfactant play in respiratory mechanics?
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Study Notes
Cardiopulmonary Physiotherapy - Review of Respiratory Physiology I
- Course: PHSI N303F Cardiopulmonary Physiotherapy
- Topic: Review of Respiratory Physiology I: Mechanics of Breathing
- Lecturer: Ms Eva Chan, Senior Lecturer, Department of Physiotherapy, HKMU
- Date: 3 Sept 2024
Learning Objectives
- Recognize the properties of pulmonary structures and their functions
- Illustrate factors contributing to airflow resistance
- Describe inspiration and expiration, explaining pressure changes during the respiratory cycle
- Explain regional differences in lung volume
- Apply breathing mechanics to pulmonary physiotherapy practice, including airflow assessment, decision-making regarding interventions (positioning, breathing exercises, secretion clearance)
Revision on Breathing
- A video demonstrating pulmonary ventilation (breathing) is available.
Properties of the Lung
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Include: airway resistance, collateral ventilation, compliance, elastic recoil, surfactant
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Key terms: respiratory mechanics; clinical implications for physiotherapists
Airway Resistance
- Resistance of the respiratory tract to airflow during inhalation and exhalation
- Calibre of the airways is inversely proportional to the 4th power of the radius (resistance is 16 times greater if radius is halved).
- Narrowed airways increase resistance
- Factors affecting calibre: bronchial smooth muscle (parasympathetic causes constriction, sympathetic causes dilation), secretion, mucosal oedema, tumour/mass, inhaled foreign body, loss of radial traction.
Bronchial Smooth Muscle
- Balanced activity between parasympathetic nervous system (bronchoconstriction) and sympathetic nervous system (bronchodilation)
Collateral Ventilation
- Airflow through interalveolar pores (Kohn), bronchiole-alveolar canals (Lambert), and interbronchial channels (Martin).
- Microscopic pathways for collateral air distribution.
Clinical Importance
- Gas can bypass obstructed airways through collateral pathways.
- Increasing lung volume aids in recruiting collateral ventilation and re-expanding collapsed alveoli.
- This helps propel sputum more proximally.
- Interventions include deep breathing with holds and secretion removal.
Compliance
- Distensibility (flexibility) of an elastic structure
- Measured as change in pulmonary volume over change in pressure
- Less compliant (stiff) at extremes of lung volume.
Elastic Recoil of the Lung
- Elastic fibers of elastin and collagen at alveolar walls and around vessels and bronchi help with lung recoil.
- Recoil helps to maintain lung shape and return to resting volume after inspiration.
Pulmonary Surfactant
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Mixture of phospholipids and apoproteins
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Synthesized and secreted by type II alveolar cells between 23 and 24 weeks gestation.
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Reduces surface tension of fluid lining alveoli, preventing their collapse.
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Clinical significance: insufficient surfactant reduces compliance leading to alveolar atelectasis and risk of pulmonary edema; neonatal Respiratory Distress Syndrome (RDS) is common in premature infants due to insufficient surfactant.
Reduced Compliance
- High pressure required to increase volume, due to: increased fibrous tissue (pulmonary fibrosis/alveolar edema), lung not being ventilated for long (atelectasis), reduced pulmonary surfactant.
Increased Compliance
- Pulmonary emphysema, aging,
Extrapulmonary Structures - Reduced Chest Wall Compliance
- Thoracic deformity, raised intra-abdominal pressure
Work of Breathing
- Work is done to move the lung and chest wall to overcome elastic and resistive forces in the airways, lungs, and chest wall.
- Approximately 80% of the work of breathing is elastic resistance.
- Approximately 20% of the work of breathing is airflow resistance.
How Do Patients Present Clinically If There Is Airflow Limitation?
- Increased work of breathing
- Shortness of Breath (SOB)
- Wheezing
- Lowered oxygen saturation (SpO2)
How Does Ventilation Happen?
- Ventilation involves a sequence of volume change -> pressure change -> gas flow.
Human Lung Model
- A model demonstrating the structure of the lungs is referenced.
Boyle's Law
- States that pressure and volume of a gas have an inverse relationship (P1V1 = P2V2).
Pulmonary Ventilation
- Movement of air into and out of the lungs.
Understanding the Terms
- Atmospheric pressure: pressure exerted by gases in the air
- Intrapulmonary pressure: pressure within the alveoli
- Intrapleural pressure: pressure within the pleural cavity
- Transpulmonary pressure: difference between intrapulmonary and intrapleural pressures
Clinical Significance–Pneumothorax
- Presence of air in the pleural space due to abnormal communication between the lung and pleural space or the atmosphere.
- Leads to lung collapse.
- Intervention: insertion of drains to restore negative pressure.
Forced Expiration Technique - Huffing
- Active Cycle Breathing Technique (ACBT) component
- Clearing peripheral airway secretions using mid to low lung volumes
- Clearing upper airway secretions with high lung volumes using coughing technique
Closing Volume
- Inspiration falls below a lower inflection point on the pressure/volume curve when closing volume is reached
- Large pressure needed to open airways/alveoli
- Closing volume increases with age, smoking, lung disease, and position (supine > upright).
Positioning
- Enhance lung volume, improve ventilation/perfusion matching, and achieve secretion drainage by manipulating patient position.
Forced Expiration at Mid to Low Lung Volumes
- Equal pressure point (EPP) shifts distally into smaller peripheral airways as lung volumes decrease.
Using More Effort
- Dynamic compression of airways due to increased effort for expiration.
Measurement of Expiratory Flow Rate
- Spirometric measurements like FEV1, FVC (forced vital capacity) are used.
- Differentiate between restrictive and obstructive lung diseases.
Positions of Equal Pressure Points
- Forced expiration at volumes above functional residual capacity (FRC) or at decreasing capacities involving lower volumes in the smaller segmental and peripheral airways.
Pre-inspiration
- Negative intrapleural pressure results from the chest wall tendency to pull outward versus the lungs tendency to pull inward.
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Description
This quiz covers the fundamental concepts of respiratory physiology as it relates to cardiopulmonary physiotherapy. You'll explore mechanics of breathing, airflow resistance, and the physiological changes that occur during inspiration and expiration. Perfect for students seeking to enhance their understanding of respiratory functions in clinical settings.