Podcast
Questions and Answers
What does the term physiology refer to?
What does the term physiology refer to?
Which statement best describes the relationship between structure and function in anatomy?
Which statement best describes the relationship between structure and function in anatomy?
Which of the following is NOT one of the four general types of tissue?
Which of the following is NOT one of the four general types of tissue?
What is likely to happen when a muscle's metabolic activity increases?
What is likely to happen when a muscle's metabolic activity increases?
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Which system is NOT mentioned as part of the introduction to organ systems?
Which system is NOT mentioned as part of the introduction to organ systems?
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How does the heart function according to the concept of functional anatomy?
How does the heart function according to the concept of functional anatomy?
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What is a key focus of physiology in studying biological function?
What is a key focus of physiology in studying biological function?
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What occurs when there is an increase in metabolic activity of a muscle?
What occurs when there is an increase in metabolic activity of a muscle?
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Which of the following correctly describes the hierarchical organization of the body?
Which of the following correctly describes the hierarchical organization of the body?
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What type of teaching approach will be used in lectures?
What type of teaching approach will be used in lectures?
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What is cell differentiation?
What is cell differentiation?
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Which type of differentiated cell is responsible for contraction and movement in the body?
Which type of differentiated cell is responsible for contraction and movement in the body?
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What is the primary function of epithelial cells?
What is the primary function of epithelial cells?
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Which of the following statements is true regarding tissues?
Which of the following statements is true regarding tissues?
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During active hyperemia, which physiological change occurs in a muscle?
During active hyperemia, which physiological change occurs in a muscle?
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What is the main role of connective tissue cells?
What is the main role of connective tissue cells?
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Which type of tissue is responsible for generating mechanical force by contraction?
Which type of tissue is responsible for generating mechanical force by contraction?
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Which of the following is NOT a function of epithelial tissue?
Which of the following is NOT a function of epithelial tissue?
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What type of muscle tissue is under voluntary control?
What type of muscle tissue is under voluntary control?
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How is nervous tissue primarily organized?
How is nervous tissue primarily organized?
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Which component is essential for the extracellular matrix (ECM) in connective tissue?
Which component is essential for the extracellular matrix (ECM) in connective tissue?
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Which of the following best defines an organ?
Which of the following best defines an organ?
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Which type of connective tissue supports body structures and includes tendons and ligaments?
Which type of connective tissue supports body structures and includes tendons and ligaments?
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Which type of tissue can be classified into simple and stratified arrangements?
Which type of tissue can be classified into simple and stratified arrangements?
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Study Notes
Course Information
- Course name: PHR3100 Human Physiology and Disease
- Year: 2025
- Instructor: Dr. Vadim V. Fedorov, Ph.D.
- Professor of Physiology and Cell Biology
- Office: 5196 Graves Hall
- Email: [email protected]
- Email subject line instructions: Include "PHR3100" and "Your Name"
Expectations
- In-class presentations and demonstrations
- Homework: Read lectures and Vander's Human Physiology textbook
- Active participation encouraged
- Question answering and asking rewarded with "The Honey Badger Badge"
Lecture Schedule
- Lecture 1: Organization of the Body (Sections 1.1-1.2)
- Lecture 2: Fluid composition and homeostasis (Sections 1.3-1.8)
- Lecture 3: Cell Membranes and Membrane Transport (Sections 3A.2; 3C.1,4.1,4.2,4.4)
- Lecture 4: Cell Receptors and Signal Transduction (Sections 5.1-5.2)
- Active fill-in notes approach for lectures
Learning Objectives
- Define Physiology and Pathophysiology
- Define Organization and "Layers" of the Body
- Define Cell and list cell functions
- List the four general types of tissue and tell their specialization
- Define Organs and Organ System
Anatomy and Physiology
- Anatomy: The study of the structure of the body
- Physiology: The study of biological function; how the body works
- Structure and function are closely interconnected (e.g., the heart's structure allows it to function as an electromechanical pump)
Functional Anatomy Examples
- The heart contracts and relaxes to pump blood
- The stomach mixes, secretes enzymes, and absorbs nutrients
Organ Systems
- The image shows the Nervous, Digestive, and Muscular systems.
Physiology Definition
- Physiology literally means the study of normal function in living systems.
- It studies biological function, from individual molecules to complex processes integrating organ functions.
- Often presented in terms of cause-and-effect sequences.
Physiology Flow Diagram Example
- Increase in muscle metabolic activity leads to increases in blood flow.
- This is due to decreased O2 and increase in metabolites in the interstitial fluid causing arteriole dilation in organs.
Approaches to Physiology
- Study organisms from components (parts and molecules, such as protein structure) to their cellular and organ function
- Integrate organ functions to understand a healthy body's operation
- Pathophysiology studies dysfunction as seen in human diseases
Organization of the Body
- Hierarchical: cells → tissues → organs → organ systems → organism
Cell Functions
- Cells exchange materials with their environment
- Cells obtain energy from organic nutrients
- Cells synthesize complex molecules
- Cells can reproduce
- Cells detect and respond to signals in their environment
Cell Differentiation
- In development, cells specialize to perform certain functions
- This specialization is called cell differentiation
Four Broad Types of Differentiated Cells
- Muscle cells (myocytes) - skeletal, cardiac, and smooth
- Neural cells (neurons)
- Epithelial cells
- Connective tissue cells
Tissues
- Tissues are an aggregate of differentiated cells with similar properties/functions
- Four general tissue types: muscle tissue, nervous tissue, epithelial tissue, and connective tissue
Muscle Cells and Tissue
- Three types—cardiac, skeletal, and smooth—are specialized to generate mechanical force by contraction.
- Skeletal Muscle is voluntary
- Cardiac and Smooth muscle are involuntary
Neurons and Nervous Tissue
- Neurons initiate, integrate and conduct electrical signals
- Neurons control the activity of other cells
- Collection of neurons forms nervous tissue (e.g. brain, spinal cord)
- Neurons form nerves to carry electrical signals
Epithelial Cells and Tissue
- Epithelial cells specialize in selective secretion, absorption, of ions and organic molecules, and protection
- Epithelial are categorized by arrangement (simple or stratified) or by shape
Connective tissue cells and Tissue
- Connective tissue cells connect, anchor, and support structures of the body
- Includes loose connective tissue, dense connective tissue, blood, cartilage, bone, and adipose tissue
- Forms extracellular matrix (ECM) that supports cells, provides attachments, and transmits information
- ECM is composed of fibrous proteins (e.g., collagen and elastin)
Organs-Organ System
- Organ: Collection of tissues serving a common function (e.g., heart, kidney)
- Organ system: Organs working together for an overall function (e.g., cardiovascular system, urinary system)
- Organism: Coordinates activities of organ systems to maintain a stable internal environment
Exam 1 Example Question
- Red Blood Cells are Connective tissue cells
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Description
Test your knowledge on key concepts from PHR3100 Human Physiology and Disease. This quiz covers topics including the organization of the body, fluid composition, cell membranes, and signal transduction. Challenge yourself and reinforce your understanding of physiology and pathophysiology principles.