Podcast
Podcast
Podcast
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Questions and Answers
Questions and Answers
What is NOT a method of transmission for TB?
What is NOT a method of transmission for TB?
- Sneezing
- Shaking hands (correct)
- Coughing
- Sharing food or drink
What is the purpose of a Tubercular Skin Test?
What is the purpose of a Tubercular Skin Test?
- To diagnose TB
- To monitor treatment progress
- To screen for TB
- To determine the risk of TB (correct)
Why is combination therapy given for the treatment of TB?
Why is combination therapy given for the treatment of TB?
- To increase the spectrum of antibiotics
- To reduce the duration of treatment
- To reduce the toxicity of individual drugs (correct)
- To target different forms of TB
What is the purpose of Directly Observed Therapy (DOTS)?
What is the purpose of Directly Observed Therapy (DOTS)?
What is the result of a high-risk Tubercular Skin Test?
What is the result of a high-risk Tubercular Skin Test?
What is the primary cause of fungal infections?
What is the primary cause of fungal infections?
What is the characteristic of polyene antifungal agents?
What is the characteristic of polyene antifungal agents?
What is a common side effect of amphotericin B?
What is a common side effect of amphotericin B?
What is the advantage of higher molecular weight fatty acids in topical antifungal agents?
What is the advantage of higher molecular weight fatty acids in topical antifungal agents?
What is the characteristic of salt forms of topical antifungal agents?
What is the characteristic of salt forms of topical antifungal agents?
What is the unique characteristic of benzoic acid as an antifungal agent?
What is the unique characteristic of benzoic acid as an antifungal agent?
What is the mechanism of action of Griseofulvin?
What is the mechanism of action of Griseofulvin?
Which of the following antifungal agents is isolated from Streptomyces noursei?
Which of the following antifungal agents is isolated from Streptomyces noursei?
What is the primary use of Clotrimazole (Canesten)?
What is the primary use of Clotrimazole (Canesten)?
Which of the following antifungal agents is an allylamine?
Which of the following antifungal agents is an allylamine?
What is the characteristic of Fluconazole among the azole antifungal agents?
What is the characteristic of Fluconazole among the azole antifungal agents?
What is the use of Naftifine HCl?
What is the use of Naftifine HCl?
What is the mechanism of action of Echinocandins?
What is the mechanism of action of Echinocandins?
What is the use of Flucytosine?
What is the use of Flucytosine?
What is the mode of transmission of Tuberculosis?
What is the mode of transmission of Tuberculosis?
What is the result of Flucytosine's inhibition of DNA and RNA synthesis?
What is the result of Flucytosine's inhibition of DNA and RNA synthesis?
What is the causative organism of Tuberculosis?
What is the causative organism of Tuberculosis?
What is theDOC for Aspergillosis?
What is theDOC for Aspergillosis?
What is the mode of action of Quinolones?
What is the mode of action of Quinolones?
What is the primary use of Benzoyl benzoate?
What is the primary use of Benzoyl benzoate?
What is the current recommended treatment phase for Pulmonary TB?
What is the current recommended treatment phase for Pulmonary TB?
What is the classification of Rifampicin?
What is the classification of Rifampicin?
What is the predecessor of all subsequently developed quinolone antibiotics?
What is the predecessor of all subsequently developed quinolone antibiotics?
What is the use of Lindane?
What is the use of Lindane?
Questions and Answers
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Flashcards
Flashcards
Purpose of TB skin test?
Purpose of TB skin test?
To determine the likelihood of TB infection.
Why combination TB therapy?
Why combination TB therapy?
To reduce toxicity and prevent drug resistance.
Purpose of Directly Observed Therapy (DOTS)?
Purpose of Directly Observed Therapy (DOTS)?
To ensure patients take their medication correctly and consistently.
High-risk TB skin test result?
High-risk TB skin test result?
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Polyene antifungal agent characteristic?
Polyene antifungal agent characteristic?
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Common side effect of Amphotericin B?
Common side effect of Amphotericin B?
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Advantage of higher MW fatty acids in topical antifungals?
Advantage of higher MW fatty acids in topical antifungals?
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Characteristic of salt forms (topical antifungals)?
Characteristic of salt forms (topical antifungals)?
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Unique characteristic of benzoic acid?
Unique characteristic of benzoic acid?
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Mechanism of action of Griseofulvin?
Mechanism of action of Griseofulvin?
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Antifungal from Streptomyces noursei?
Antifungal from Streptomyces noursei?
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Primary use of Clotrimazole (Canesten)?
Primary use of Clotrimazole (Canesten)?
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Which antifungal is an allylamine?
Which antifungal is an allylamine?
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Characteristic of Fluconazole?
Characteristic of Fluconazole?
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Use of Naftifine HCl?
Use of Naftifine HCl?
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Mechanism of action of Echinocandins?
Mechanism of action of Echinocandins?
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Use of Flucytosine?
Use of Flucytosine?
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Transmission mode of Tuberculosis?
Transmission mode of Tuberculosis?
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Flucytosine's inhibition result?
Flucytosine's inhibition result?
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Causative organism of Tuberculosis?
Causative organism of Tuberculosis?
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DOC for Aspergillosis?
DOC for Aspergillosis?
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Quinolones mode of action?
Quinolones mode of action?
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Primary use of Benzoyl benzoate?
Primary use of Benzoyl benzoate?
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Current TB treatment phase?
Current TB treatment phase?
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Classification of Rifampicin?
Classification of Rifampicin?
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Predecessor of quinolone antibiotics?
Predecessor of quinolone antibiotics?
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Use of Lindane?
Use of Lindane?
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Flashcards
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Study Notes
Study Notes
Tuberculosis (TB)
- Cause: Mycobacterium tuberculosis bacteria
- Spread: Through air from one person to another
- Not everyone infected becomes sick; two conditions exist: latent TB infection (LTBI) and TB disease
- TB bacteria can attack any part of the body, such as the lungs, kidney, spine, and brain
- If not treated, TB disease can be fatal
Diagnosis
- Chest X-ray
- AFB Screening
- Tubercular Skin Test
- >15mm: low risk
- >10mm: high risk
- >5mm: immunocompromised
Treatment
- Combination therapy: To broaden spectrum, reduce toxicity, and prevent resistance
- Directly Observed Therapy (DOTS)
- Trained designated person watches patient swallow each dose of anti-TB drugs and documents it
- Helps ensure patients adhere to therapy
Anti-Tubercular Agents
- Classified as:
- Bactericidal
- Bacteriostatic
- Examples:
- Rifampicin
- Isoniazid
- Ethambutol
- Pyrazinamide
- Streptomycin
Antifungal Agents
- Classification:
- Polyenes
- Griseofulvin
- Allylamines
- Azoles
- Echinocandins
- Flucytosine
- Examples:
- Amphotericin B
- Nystatin
- Clotrimazole
- Ketoconazole
- Fluconazole
- Terbinafine
- Naftifine
- Itraconazole
- Capsofungin
- Micafungin
Scabicides and Pediculicides
- Scabivides: compounds used to control mites (Sarcoptes scabiei)
- Pediculicides: used to eliminate head, body, crab lice, and fleas
- Examples:
- Benzoyl benzoate
- Lindane
- Crotamiton
- Permethrin
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