Podcast
Questions and Answers
What is NOT a method of transmission for TB?
What is NOT a method of transmission for TB?
- Sneezing
- Shaking hands (correct)
- Coughing
- Sharing food or drink
What is the purpose of a Tubercular Skin Test?
What is the purpose of a Tubercular Skin Test?
- To diagnose TB
- To monitor treatment progress
- To screen for TB
- To determine the risk of TB (correct)
Why is combination therapy given for the treatment of TB?
Why is combination therapy given for the treatment of TB?
- To increase the spectrum of antibiotics
- To reduce the duration of treatment
- To reduce the toxicity of individual drugs (correct)
- To target different forms of TB
What is the purpose of Directly Observed Therapy (DOTS)?
What is the purpose of Directly Observed Therapy (DOTS)?
What is the result of a high-risk Tubercular Skin Test?
What is the result of a high-risk Tubercular Skin Test?
What is the primary cause of fungal infections?
What is the primary cause of fungal infections?
What is the characteristic of polyene antifungal agents?
What is the characteristic of polyene antifungal agents?
What is a common side effect of amphotericin B?
What is a common side effect of amphotericin B?
What is the advantage of higher molecular weight fatty acids in topical antifungal agents?
What is the advantage of higher molecular weight fatty acids in topical antifungal agents?
What is the characteristic of salt forms of topical antifungal agents?
What is the characteristic of salt forms of topical antifungal agents?
What is the unique characteristic of benzoic acid as an antifungal agent?
What is the unique characteristic of benzoic acid as an antifungal agent?
What is the mechanism of action of Griseofulvin?
What is the mechanism of action of Griseofulvin?
Which of the following antifungal agents is isolated from Streptomyces noursei?
Which of the following antifungal agents is isolated from Streptomyces noursei?
What is the primary use of Clotrimazole (Canesten)?
What is the primary use of Clotrimazole (Canesten)?
Which of the following antifungal agents is an allylamine?
Which of the following antifungal agents is an allylamine?
What is the characteristic of Fluconazole among the azole antifungal agents?
What is the characteristic of Fluconazole among the azole antifungal agents?
What is the use of Naftifine HCl?
What is the use of Naftifine HCl?
What is the mechanism of action of Echinocandins?
What is the mechanism of action of Echinocandins?
What is the use of Flucytosine?
What is the use of Flucytosine?
What is the mode of transmission of Tuberculosis?
What is the mode of transmission of Tuberculosis?
What is the result of Flucytosine's inhibition of DNA and RNA synthesis?
What is the result of Flucytosine's inhibition of DNA and RNA synthesis?
What is the causative organism of Tuberculosis?
What is the causative organism of Tuberculosis?
What is theDOC for Aspergillosis?
What is theDOC for Aspergillosis?
What is the mode of action of Quinolones?
What is the mode of action of Quinolones?
What is the primary use of Benzoyl benzoate?
What is the primary use of Benzoyl benzoate?
What is the current recommended treatment phase for Pulmonary TB?
What is the current recommended treatment phase for Pulmonary TB?
What is the classification of Rifampicin?
What is the classification of Rifampicin?
What is the predecessor of all subsequently developed quinolone antibiotics?
What is the predecessor of all subsequently developed quinolone antibiotics?
What is the use of Lindane?
What is the use of Lindane?
Study Notes
Tuberculosis (TB)
- Cause: Mycobacterium tuberculosis bacteria
- Spread: Through air from one person to another
- Not everyone infected becomes sick; two conditions exist: latent TB infection (LTBI) and TB disease
- TB bacteria can attack any part of the body, such as the lungs, kidney, spine, and brain
- If not treated, TB disease can be fatal
Diagnosis
- Chest X-ray
- AFB Screening
- Tubercular Skin Test
- >15mm: low risk
- >10mm: high risk
- >5mm: immunocompromised
Treatment
- Combination therapy: To broaden spectrum, reduce toxicity, and prevent resistance
- Directly Observed Therapy (DOTS)
- Trained designated person watches patient swallow each dose of anti-TB drugs and documents it
- Helps ensure patients adhere to therapy
Anti-Tubercular Agents
- Classified as:
- Bactericidal
- Bacteriostatic
- Examples:
- Rifampicin
- Isoniazid
- Ethambutol
- Pyrazinamide
- Streptomycin
Antifungal Agents
- Classification:
- Polyenes
- Griseofulvin
- Allylamines
- Azoles
- Echinocandins
- Flucytosine
- Examples:
- Amphotericin B
- Nystatin
- Clotrimazole
- Ketoconazole
- Fluconazole
- Terbinafine
- Naftifine
- Itraconazole
- Capsofungin
- Micafungin
Scabicides and Pediculicides
- Scabivides: compounds used to control mites (Sarcoptes scabiei)
- Pediculicides: used to eliminate head, body, crab lice, and fleas
- Examples:
- Benzoyl benzoate
- Lindane
- Crotamiton
- Permethrin
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Description
Learn about antifungal agents, types of fungal infections, and how they affect the human body. Understand the differences between superficial, subcutaneous, and systemic infections. Test your knowledge on medicinal chemistry and pharmacology!
