Topical Antifungal Agents Overview

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Questions and Answers

What is the primary effect of topical antifungal agents on fungal cells?

They alter the cell membrane to increase permeability and induce leakage. (correct)
They inhibit replication of fungal DNA specifically.
They completely kill fungal cells without affecting surrounding cells.
They enhance the ability of fungi to absorb nutrients.

Which of the following is NOT a condition treated by topical antifungal agents?

Tinea corporis
Candidiasis in the bloodstream (correct)
Diaper rash
Oral thrush

Which of the following antifungal agents is commonly used to treat athlete's foot?

Clotrimazole (correct)
Voriconazole
Nystatin
Fluconazole

What is a shared characteristic of Tinea pedis, Tinea corporis, and Candida albicans in relation to antifungal treatment?

<p>They are fungal infections suitable for topical antifungal agents. (C)</p> Signup and view all the answers

Which of the following statements regarding the mechanism of action of topical antifungal agents is accurate?

<p>They disrupt cell membrane function leading to nutrient leakage. (D)</p> Signup and view all the answers

Flashcards

How do topical antifungal agents work?

Topical antifungal agents work by changing the fungal cell membrane, making it more leaky and preventing the fungal cell from taking in essential nutrients. This disrupts the fungus's growth and ability to survive.

What are topical antifungal agents used for?

Topical antifungal agents are used to treat fungal infections that affect the skin, such as athlete's foot, jock itch, ringworm, and diaper rash.

Can topical antifungal agents treat infections caused by Candida albicans?

Candida albicans is a type of fungus that can cause infections like oral thrush. Topical antifungal agents are used to treat these infections.

Give examples of topical antifungal agents.

Clotrimazole, ketoconazole, miconazole, and nystatin are examples of topical antifungal agents commonly used to treat fungal infections.

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How are topical antifungal agents applied?

Topical antifungal agents are applied directly to the affected area of the skin.

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Study Notes

Topical Antifungal Agents

Topical antifungal agents disrupt fungal cell membranes, increasing permeability and causing leakage of essential molecules. This damages the fungus, impairing nutrient uptake and growth.
These agents treat various superficial fungal infections:
- Tinea pedis (athlete's foot)
- Tinea corporis (ringworm)
- Candida albicans infections (e.g., oral thrush, diaper rash)
- Jock itch
Common antifungal agents used topically include:
- Clotrimazole
- Ketoconazole
- Miconazole
- Nystatin