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Questions and Answers

What is the process of moving a substance from the site of administration across a body membrane to circulating body fluids called?

  • Distribution
  • Absorption (correct)
  • Metabolism
  • Excretion
  • Which medication is contraindicated with concurrent use of nitroglycerin due to the risk of hypotension?

  • Sildenafil (correct)
  • Albuterol
  • Ibuprofen
  • Risperidone
  • What is the term for a large initial dose of medication used to rapidly achieve therapeutic concentration in the body?

  • Maintenance Dose
  • Loading Dose (correct)
  • Pediatric Dose
  • Bolus Dose
  • Which medication is primarily used for treating MRSA but also poses a risk of nephrotoxicity?

    <p>Vancomycin</p> Signup and view all the answers

    What should be increased in the diet while taking psyllium to enhance its effectiveness?

    <p>Fiber and Fluids</p> Signup and view all the answers

    Which medication is known to suppress immune response to relieve congestion?

    <p>Fluticasone</p> Signup and view all the answers

    What is the common adverse effect associated with antibiotics that can indicate a serious condition?

    <p>Foul smelling diarrhea</p> Signup and view all the answers

    Which route of administration bypasses the first-pass effect and is used cautiously in liver failure?

    <p>Intravenous</p> Signup and view all the answers

    Which medication is primarily known for its cough-suppressing properties and must be questioned for concurrent opioid use?

    <p>Codeine</p> Signup and view all the answers

    High blood sugar is most commonly associated with which of the following?

    <p>Total Parenteral Nutrition (TPN)</p> Signup and view all the answers

    What is the most serious adverse effect associated with metoclopramide?

    <p>Tardive dyskinesia</p> Signup and view all the answers

    Which medication is primarily used to prevent airway edema and inflammation?

    <p>Montelukast</p> Signup and view all the answers

    What mechanism of action is involved with NSAIDs in the treatment of pain?

    <p>Blocking cyclooxygenase enzymes</p> Signup and view all the answers

    Which of the following is a contraindication for administering sulfamethoxazole?

    <p>Pregnancy</p> Signup and view all the answers

    What is the primary purpose of using finasteride?

    <p>To reduce symptoms of enlarged prostate</p> Signup and view all the answers

    Which medication is useful for treating purely manic or depressive episodes with a narrow therapeutic window?

    <p>Lithium</p> Signup and view all the answers

    Which medication helps to empty the stomach and is indicated for nausea?

    <p>Metoclopramide</p> Signup and view all the answers

    In pharmacokinetics, which of the following correctly describes the order of processes?

    <p>Absorption, Distribution, Metabolism, Excretion</p> Signup and view all the answers

    What medication is contraindicated for use in patients allergic to soybeans, peanuts, or soy lecithin?

    <p>Ipratropium</p> Signup and view all the answers

    Which route of administration is the fastest for delivering medication effects?

    <p>IV</p> Signup and view all the answers

    What type of fluid is Lactated Ringers considered?

    <p>Isotonic</p> Signup and view all the answers

    Which medication is specifically indicated for the treatment of fungal infections?

    <p>Nystatin</p> Signup and view all the answers

    What condition can lead to decreased drug excretion and increased toxicity?

    <p>End stage renal disease</p> Signup and view all the answers

    Which of the following is a common adverse effect related to theophylline use?

    <p>Tremors</p> Signup and view all the answers

    What is the primary use of Naloxone?

    <p>Reversing opiate overdose</p> Signup and view all the answers

    Which medication is known to have its effectiveness decreased by the concurrent use of steroids and is classified as an NSAID?

    <p>Aspirin</p> Signup and view all the answers

    Which medication is recommended for gout management, and how long does it typically take to lower uric acid levels?

    <p>Allopurinol; 1-3 weeks</p> Signup and view all the answers

    What class of drug is Omeprazole, and what condition does it treat?

    <p>PPI; peptic ulcer disease</p> Signup and view all the answers

    Which term describes severe reactions such as hives or anaphylaxis following medication use?

    <p>Adverse effects</p> Signup and view all the answers

    Ciprofloxacin should be taken with or without food, but which of the following can decrease its absorption?

    <p>Antacids</p> Signup and view all the answers

    What side effects are commonly associated with the use of theophylline?

    <p>Tachycardia, hypertension, and insomnia</p> Signup and view all the answers

    Which medication is classified as an NSAID and has its effectiveness decreased by steroids?

    <p>Aspirin</p> Signup and view all the answers

    Which condition is characterized by a significant decrease in drug excretion, potentially leading to drug toxicity?

    <p>End Stage Renal Disease (ESRD)</p> Signup and view all the answers

    What is the primary use of Nystatin?

    <p>Fungal infections</p> Signup and view all the answers

    What type of fluid is 0.45% sodium chloride considered?

    <p>Hypotonic fluid</p> Signup and view all the answers

    What is the mechanism of action of Cilastatin when used with Imipenem?

    <p>Beta-lactamase inhibition</p> Signup and view all the answers

    For which condition is allopurinol prescribed, and how long does it typically take to lower uric acid levels?

    <p>Gout; 1-3 weeks</p> Signup and view all the answers

    What is commonly regarded as an adverse effect resulting from medication use?

    <p>Hives and anaphylaxis</p> Signup and view all the answers

    What is the most serious adverse effect associated with metoclopramide treatment?

    <p>Tardive dyskinesia</p> Signup and view all the answers

    What is the primary mechanism of action for montelukast?

    <p>Blocking leukotriene receptors</p> Signup and view all the answers

    Which medication is specifically used for ulcerative colitis but does not cure the disease?

    <p>Sulfasalazine</p> Signup and view all the answers

    Which of the following medications is contraindicated for patients who are allergic to soybeans and peanuts?

    <p>Ipratropium</p> Signup and view all the answers

    What common side effect can occur with the use of diphenhydramine?

    <p>Dry mouth</p> Signup and view all the answers

    Which route of medication administration is considered the fastest in terms of effectiveness?

    <p>IV</p> Signup and view all the answers

    What therapeutic window characteristic is significant for lithium treatment?

    <p>Narrow therapeutic window</p> Signup and view all the answers

    What is one of the primary uses for the medication finasteride?

    <p>Promoting prostate shrinkage</p> Signup and view all the answers

    What is the primary characteristic of antibiotics concerning hormone treatments like estradiol?

    <p>Antibiotics reduce the effectiveness of estradiol</p> Signup and view all the answers

    Which mechanism of action describes how drugs are moved to and from the blood and various tissues?

    <p>Distribution</p> Signup and view all the answers

    Which medication is known to potentially cause oral candidiasis as a side effect?

    <p>Fluticasone</p> Signup and view all the answers

    What is the consequence of concurrent use of CNS depressants with morphine?

    <p>Increased risk of overdose</p> Signup and view all the answers

    What kind of medication is Risperidone primarily classified as?

    <p>Atypical antipsychotic</p> Signup and view all the answers

    What is the function of a spacer when using inhaled medications?

    <p>To ensure more medication reaches the lungs</p> Signup and view all the answers

    What effect does the first-pass metabolism have on medication effectiveness?

    <p>Decreases the medication effects</p> Signup and view all the answers

    Which adverse effect is particularly concerning with the use of Vancomycin?

    <p>Oliguria</p> Signup and view all the answers

    What property does a loading dose of medication generally have?

    <p>It is a large initial dose to quickly achieve a therapeutic effect</p> Signup and view all the answers

    What is the primary action of the medication codeine?

    <p>It acts as a cough suppressant</p> Signup and view all the answers

    Study Notes

    Side Effects and Management

    • Nausea and itching can be managed at home as common side effects.
    • Adverse effects may include hives, severe rash, or anaphylaxis.

    Medication Classifications

    • Lactated Ringer's is a crystalloid fluid that is isotonic, preventing major compartment shifts.
    • Ciproflaxcin is an antibiotic that can be taken with or without food; antacids reduce absorption.
    • Nystatin treats fungal infections and is available in various forms such as capsules and creams.

    Drug Specifics and Considerations

    • Theophylline is used for asthma; it has multiple side effects including tachycardia and insomnia.
    • Aspirin effectiveness can decrease with steroid use; it is classified as an NSAID.
    • Allopurinol is taken with food to treat gout, requiring 1-3 weeks to affect uric acid levels.
    • Omeprazole is a PPI that treats peptic ulcer disease.
    • Famotidine is an OTC or prescription option for GERD treatment.

    Special Drug Administration and Precautions

    • Oxytocin stimulates labor and should be monitored for rapid contractions requiring intervention.
    • Naloxone is used to treat opiate overdose; respiratory depression is a key sign.
    • Morphine causes peripheral vasodilation leading to orthostatic hypotension and requires careful monitoring.
    • Potassium IV should be delivered at a concentration of 1mEq per 10ml, with a maximum rate of 10mEq/hr; never give IV push.

    Pharmacological Principles

    • Absorption refers to the movement of substances across body membranes into body fluids.
    • The first-pass effect is the medication metabolization in the liver bypassed by IV administration.
    • A loading dose provides a large initial dose to quickly achieve therapeutic concentrations.

    Drug Interactions and Effects

    • Estradiol's effectiveness can be diminished by antibiotics; smoking should be questioned.
    • Macrolides are bacteriostatic, inhibiting protein synthesis.
    • Ibuprofen may cause gastrointestinal bleeding; monitor kidney patients for increased creatinine levels.

    Treatment Modalities

    • Trimethoprim-sulfamethoxazole is used to treat UTIs.
    • Montelukast is a leukotriene modifier that can cause rare but serious side effects like suicidal thoughts.
    • Diphendydramine is used in Parkinson's treatment and may lead to urinary retention and dry mouth.

    Drug Delivery and Kinetics

    • Space devices ensure that more medication is delivered into the lungs.
    • Pharmacokinetics includes absorption, distribution, metabolism, and excretion—summarized as ADME.
    • IV, sublingual, oral liquid, oral tablets, and oral enteric-coated represent routes from fastest to slowest effectiveness.

    Additional Considerations

    • Acetaminophen treats pain, especially for patients with a history of ulcers.
    • Lithium is effective for manic/depressive episodes but has a narrow therapeutic window and many drug interactions.
    • Use caution with medications that cannot be crushed, including extended release or enteric-coated formulations.

    Side Effects and Management

    • Nausea and itching can be managed at home as common side effects.
    • Adverse effects may include hives, severe rash, or anaphylaxis.

    Medication Classifications

    • Lactated Ringer's is a crystalloid fluid that is isotonic, preventing major compartment shifts.
    • Ciproflaxcin is an antibiotic that can be taken with or without food; antacids reduce absorption.
    • Nystatin treats fungal infections and is available in various forms such as capsules and creams.

    Drug Specifics and Considerations

    • Theophylline is used for asthma; it has multiple side effects including tachycardia and insomnia.
    • Aspirin effectiveness can decrease with steroid use; it is classified as an NSAID.
    • Allopurinol is taken with food to treat gout, requiring 1-3 weeks to affect uric acid levels.
    • Omeprazole is a PPI that treats peptic ulcer disease.
    • Famotidine is an OTC or prescription option for GERD treatment.

    Special Drug Administration and Precautions

    • Oxytocin stimulates labor and should be monitored for rapid contractions requiring intervention.
    • Naloxone is used to treat opiate overdose; respiratory depression is a key sign.
    • Morphine causes peripheral vasodilation leading to orthostatic hypotension and requires careful monitoring.
    • Potassium IV should be delivered at a concentration of 1mEq per 10ml, with a maximum rate of 10mEq/hr; never give IV push.

    Pharmacological Principles

    • Absorption refers to the movement of substances across body membranes into body fluids.
    • The first-pass effect is the medication metabolization in the liver bypassed by IV administration.
    • A loading dose provides a large initial dose to quickly achieve therapeutic concentrations.

    Drug Interactions and Effects

    • Estradiol's effectiveness can be diminished by antibiotics; smoking should be questioned.
    • Macrolides are bacteriostatic, inhibiting protein synthesis.
    • Ibuprofen may cause gastrointestinal bleeding; monitor kidney patients for increased creatinine levels.

    Treatment Modalities

    • Trimethoprim-sulfamethoxazole is used to treat UTIs.
    • Montelukast is a leukotriene modifier that can cause rare but serious side effects like suicidal thoughts.
    • Diphendydramine is used in Parkinson's treatment and may lead to urinary retention and dry mouth.

    Drug Delivery and Kinetics

    • Space devices ensure that more medication is delivered into the lungs.
    • Pharmacokinetics includes absorption, distribution, metabolism, and excretion—summarized as ADME.
    • IV, sublingual, oral liquid, oral tablets, and oral enteric-coated represent routes from fastest to slowest effectiveness.

    Additional Considerations

    • Acetaminophen treats pain, especially for patients with a history of ulcers.
    • Lithium is effective for manic/depressive episodes but has a narrow therapeutic window and many drug interactions.
    • Use caution with medications that cannot be crushed, including extended release or enteric-coated formulations.

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    Description

    Test your knowledge on common side effects, medications, and their classifications. This quiz covers various aspects such as trade names and specific treatments for conditions like asthma and fungal infections. Enhance your understanding of pharmacology with these key concepts.

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