Pharmacy Practice Quizzes and Exams Guidance
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Questions and Answers

What are the diagnostic criteria for chronic idiopathic constipation (CIC)?

  • Symptoms for ≥ 3 months and ≥ 2 of the listed symptoms
  • Symptoms for ≥ 12 months and ≥ 2 of the listed symptoms
  • Symptoms for ≥ 6 months and ≥ 2 of the listed symptoms (correct)
  • Symptoms for ≥ 6 months and ≥ 3 of the listed symptoms

    • Which of the following is an example of an agent that causes softening of feces in 1-3 days?

  • Bisacodyl
  • Methylcellulose (correct)
  • Magnesium citrate
  • Senna

    • What is the role of Lactulose in the treatment of constipation?

  • It is a prokinetic agent
  • It causes immediate watery evacuation
  • It acts as an intestinal secretagogue
  • It increases stool frequency by reaching the large bowel (correct)

    • Which agent causes watery evacuation within 1-6 hours?

    <p>Bisacodyl</p> Signup and view all the answers

    What lifestyle changes are recommended in the initial management for chronic idiopathic constipation?

    <p>Increasing fluid intake</p> Signup and view all the answers

    Which medication is classified as an osmotic laxative?

    <p>Lactulose</p> Signup and view all the answers

    What is the typical administration schedule for the oral solution mentioned in the text?

    <p>Once daily</p> Signup and view all the answers

    Which side effect is specifically mentioned in relation to Miralax and lactulose in the text?

    <p>Flatulence</p> Signup and view all the answers

    When should stimulant laxatives like bisacodyl or senna be used according to the text?

    <p>Occasional use or rescue therapy</p> Signup and view all the answers

    What would be the next step if fiber is partially effective or not effective at all according to the treatment pearls in the text?

    <p>Add an osmotic laxative for 2-4 weeks</p> Signup and view all the answers

    What is a key monitoring consideration highlighted in the text regarding long-term use of specific medications?

    <p>Monitor for <strong>electrolyte imbalance</strong></p> Signup and view all the answers

    What are the treatment goals mentioned in the text for managing constipation?

    <p><strong>Relieve symptoms and re-establish normal bowel habits</strong></p> Signup and view all the answers

    What is the MOA of Prucalopride (Motegrity)?

    <p>It is a GI prokinetic agent that stimulates colonic peristalsis</p> Signup and view all the answers

    In the 12-week studies, how many bowel movements per week did patients need to have, on average, with Prucalopride (Motegrity)?

    <p>At least 3 bowel movements per week</p> Signup and view all the answers

    What is a contraindication for using Prucalopride (Motegrity)?

    <p>Crohn's disease</p> Signup and view all the answers

    How should Prucalopride (Motegrity) be administered?

    <p>Orally once daily, with or without food</p> Signup and view all the answers

    What side effect should patients using Prucalopride (Motegrity) watch out for?

    <p>Headache</p> Signup and view all the answers

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